A5002202879- Cervical Cancer and HPV Research
- Genital Health and Disease
- Hepatitis B Virus Studies
- Reproductive tract infections research
- Urological Disorders and Treatments
- Antibiotic Resistance in Bacteria
- Virus-based gene therapy research
- Parvovirus B19 Infection Studies
- Infections and bacterial resistance
- Colorectal and Anal Carcinomas
- Molecular Biology Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Syphilis Diagnosis and Treatment
- Viral-associated cancers and disorders
- Animal Disease Management and Epidemiology
- HIV/AIDS Research and Interventions
- Women's cancer prevention and management
- Infectious Diseases and Mycology
- Pharmaceutical and Antibiotic Environmental Impacts
- Adipose Tissue and Metabolism
- Global Cancer Incidence and Screening
- Animal Virus Infections Studies
- Fatty Acid Research and Health
- Herpesvirus Infections and Treatments
- Viral gastroenteritis research and epidemiology
Universidade de São Paulo
2022
Universidade Federal do Espírito Santo
2009-2021
HPV16 accounts for 50-70% of cervical cancer cases worldwide. Characterization variants previously indicated that they differ in risks viral persistence, progression to precancer and malignant cancer. The aim this study was examine the association severity disease with identified specimens (n = 281) obtained from a Cervical Pathology Colposcopy outpatient clinic University Hospital Espírito Santo State, Southeastern Brazil, April 2010 November 2011. All cytologic histologic diagnoses were...
Objective To estimate the prevalence of anal HPV infection, genotype distribution, intraepithelial neoplasia (AIN) and correlates in a cohort HIV-infected patients attending at Sexually Transmitted Infections (STI) clinic Brazil. Study design A descriptive analysis was performed which includes, demographic, behavioral clinical data. Anal specimens from HIV-positive men women were collected during regular visit they used for cytology histopathology tests, as well molecular identification....
Human Immunodeficiency Virus (HIV)-seropositive women are more likely to have anogenital cancer, and high risk-HPV (HR-HPV) infection is the main associated factor. Between August 2013 December 2015, we conducted a descriptive study determine HPV genotypes HPV16 variants in cervical anal samples of HIV-seropositive with normal Pap test. The viral DNA was amplified by PCR using PGMY09/11 set primers. Reverse line blot (RLB), restriction fragment length polymorphism (RFLP) sequencing assays...
Background Although screening for cervical cancer is recommended women in most countries, the incidence of greater developing countries. Our goal was to determine prevalence and factors associated with high-grade lesions/cervical among attending a reference clinic Brazil evaluate correlation histology cytology, colposcopy high-risk HPV (HR-HPV) tests. Methods A cross-sectional study carried out. The patients were interviewed collect demographic, epidemiological clinical data. Specimens...
We conducted a cross-sectional study in Vitória, Brazil, to assess the prevalence of human papillomavirus (HPV) infection HIV-positive and HIV-negative women attending sexually transmitted (STI)/AIDS clinic. also investigated presence HPV genotypes assessed covariates for HIV infection. Enrolled patients received gynecological evaluation, cervical scrape samples were collected cytological analysis HPV-DNA polymerase chain reaction (PCR). A blood sample was obtained determine status. squamous...
Given the causal relationship between specific types of HPV with cervical cancer and precursor lesions, it is important to identify viral type involved. The aim this study access prevalence in HIV seropositive seronegative women. Accordingly, 77 positive samples were obtained from 284 women (seropositive (n=112) (n=172) for HIV) who attended a Sexually Transmitted Infection clinic, Vitoria, Southeastern Brazil. Viral DNA was amplified by PCR using MY09/MY11 degenerated primers genotyping...
Early miscarriage is still a concern, and viral infections are recognised as one of the causes this adverse outcome. The causal relationship between HPV remains controversial. aim study was to evaluate whether infection indeed may occur in both maternal placental tissue cases miscarriage. Decidual chorionic villi fragments (n = 118) were dissected from 81 cases, 68 spontaneous 13 intentional. DNA detected using consensus primers MY09/11; eight (9.9%, 8/81), seven which (10.3%) miscarriages...
This study investigated the prevalence of adeno-associated virus (AAV) and human papillomavirus (HPV) DNA in cervical samples HIV-seropositive -seronegative women attending a clinic south-eastern Brazil. Both viruses were by polymerase chain reaction (PCR) cytological exams performed. AAV was typed PCR restriction fragment length polymorphism analysis. 19.7% (56/284), with 18.7% (21/112) 20.3% (35/172) HIV-positive -negative women, respectively. type 2 single detected. detected higher...
Pregnancy failure is a common event and often of unknown cause. Some viruses are thought to cause abortions including the adeno-associated (AAV), which regarded as being without any definitive association human disease. This study investigated AAV infection in 81 abortions, both spontaneous intentional that occurred up 23rd week gestation. Nucleic acid AAV-2, 3, 5 types from 118 decidual chorionic tissues, collected patients this study, was amplified by nested-PCR. In situ hybridization...
Clinical improvements following highly active antiretroviral therapy (HAART) may increase high-risk behaviors resulting in sexually transmitted infections (STI). Optimism related to the success of HAART slowing disease progression, reducing viral load, and improving health status might be important factors for increasing sexual risk such as less use condoms.To determine prevalence Chlamydia trachomatis, Neisseria gonorrhoeae, syphilis, hepatitis B C, HPV, cervical cytological abnormalities...
Abstract Background The high-risk human papillomavirus (HR-HPV) infection is the main cause of cervical cancer development, and most common types were included in last approved nonavalent vaccine (9vHPV). Geographical, socioeconomic ethnic barriers developing countries challenge primary secondary prevention measures cancer. We aimed to determine prevalence HPV viral load HR-HPV 9vHPV-related black women resident rural semi-isolated communities. Methods A descriptive study was conducted with...
Enteroaggregative Escherichia coli (EAEC), a highly heterogeneous pathotype of E. classified as typical and atypical, are an emerging cause acute persistent diarrhea. We aimed to investigate whether population living in rural geographic areas, impacts the heterogeneity, dissemination antimicrobial susceptibility EAEC strains. isolates (n=73) were analysed for presence 23 putative virulence factors, plasmid resistance profiles, biofilm formation, pulsedfield gel electrophoresis (PFGE) by...
The aim of this study was to identify the differentially expressed genes (DEG) from skeletal muscle and liver samples animal model for metabolic diseases in human. To perform study, fatty acid (FA) profile RNA sequencing (RNA-Seq) data 35 tissue (SOY1.5, n=17 SOY3.0, n=18) 36 n=18 Large White pigs were analyzed. FA tissues modified by diet, mainly those related monounsaturated (MUFA) polyunsaturated (PUFA) FA. transcriptome analysis revealed 45 DEG (FDR 10%), functional enrichment identified...