A5066825043- Diverticular Disease and Complications
- Appendicitis Diagnosis and Management
- Gastrointestinal disorders and treatments
- Colorectal Cancer Surgical Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Anorectal Disease Treatments and Outcomes
- Head and Neck Cancer Studies
- Sarcoma Diagnosis and Treatment
- Pelvic floor disorders treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Colorectal and Anal Carcinomas
- Infectious Diseases and Tuberculosis
- Colorectal Cancer Screening and Detection
- Ear and Head Tumors
- Proteoglycans and glycosaminoglycans research
- Tracheal and airway disorders
- Ear Surgery and Otitis Media
- Minimally Invasive Surgical Techniques
- Hip disorders and treatments
- Otolaryngology and Infectious Diseases
- Fibroblast Growth Factor Research
- Vascular Malformations and Hemangiomas
- Surgical Simulation and Training
- Surgical site infection prevention
- Streptococcal Infections and Treatments
Akershus University Hospital
2015-2025
Oslo University Hospital
2023-2025
University of Oslo
2015-2025
University of St. Gallen
1991-2023
Winterthur Museum Garden and Library
1991-2023
Helios Klinikum Krefeld
2020-2023
European Neuroendocrine Tumor Society
2017
Universitätsklinikum Würzburg
2017
University of Otago
2016
Christchurch Hospital
2016
Perforated colonic diverticulitis usually requires surgical resection, which is associated with significant morbidity. Cohort studies have suggested that laparoscopic lavage may treat perforated less morbidity than resection procedures.To compare the outcomes from those for colon diverticulitis.Multicenter, randomized clinical superiority trial recruiting participants 21 centers in Sweden and Norway February 2010 to June 2014. The last patient follow-up was December 2014 final review...
The goal of this European Society Coloproctology (ESCP) guideline project is to give an overview the existing evidence on management diverticular disease, primarily as a guidance surgeons.The was developed during several working phases including three voting rounds and one consensus meeting. two leads (JKS EA) appointed by ESCP committee together with member (WB) agreed methodology, decided six themes for groups (WGs) drafted list research questions. Senior WG members, mostly colorectal...
Abstract Background Recent randomized trials demonstrated that laparoscopic lavage compared with resection for Hinchey III perforated diverticulitis was associated similar mortality, less stoma formation but a higher rate of early reintervention. The aim this study to compare 1-year outcomes in patients who participated the Scandinavian Diverticulitis (SCANDIV) trial. Methods Between February 2010 and June 2014, from 21 hospitals Norway Sweden presenting suspected were enrolled multicentre...
Perforated colonic diverticulitis usually requires surgical resection, with significant morbidity. Short-term results from randomized clinical trials have indicated that laparoscopic lavage is a feasible alternative to resection. However, it appears no long-term are available.To compare (5-year) outcomes of peritoneal and primary resection as treatments perforated purulent diverticulitis.This international multicenter trial was conducted in 21 hospitals Sweden Norway, which enrolled patients...
The creation of functional muscles/muscle tissue from human stem cells is a major goal skeletal muscle engineering. Mesenchymal (MSCs) fat/adipose (AT-MSCs), as well bone marrow (BM-MSCs) have been shown to bear myogenic potential, which makes them candidate for engineering applications. aim this study was analyse the differentiation potential AT-MSCs and BM-MSCs cultured in six different cell culture media containing mixtures growth factors. following were used our experiments: mesenchymal...
Giant Colonic Diverticulum (GCD) is a rare but potentially life-threatening complication of diverticular disease, defined as diverticulum larger than 4 cm, most commonly arising in the sigmoid colon. Its rarity could lead to diagnostic delays and mismanagement. A 64-year-old Caucasian female presented with persistent abdominal pain swelling. Examination revealed palpable mass left flank. computed tomography (CT) scan demonstrated an 11x10x14 cm air-filled cavity adjacent colon, initially...
Abstract Aim Accumulated data suggest that routine use of defunctioning stoma in low anterior resection for rectal cancer may cause kidney injury, bowel dysfunction and a higher risk permanent stomas. We aim to study whether avoidance diverting selected patients is safe reduces adverse consequences. Methods SELSA multicentre international prospective observational nesting an open‐label randomized clinical trial. All with primary planned are eligible. Patients operated curative intent, aged...
Abstract Aim This study aimed to evaluate the implementation of nonantibiotic management acute uncomplicated diverticulitis at a large university hospital in Norway with regard failure, disease recurrence and complications. Method On 1 January 2013 we implemented new policy for without antibiotics. Antibiotic treatment was only provided case defined criteria. All patients admitted from 30 June 2014 CT ‐verified, left‐sided, were included evaluated retrospectively, 12 months’ follow‐up....
Abstract Aim Routine colonoscopy to exclude colorectal cancer (CRC) after CT‐verified acute diverticulitis is controversial. This study aimed compare the incidence of CRC in patients with that general population. Method Patients an emergency admission for diverticular disease any Norwegian hospital between 1 January 2008 and 31 December 2010 were included through identification Patient Registry using International Classification Diseases (ICD‐10) codes K57.1‐9. To estimate age‐specific...
Abstract Methods Recent randomized control trials (RCTs) have confirmed that antibiotics in acute uncomplicated diverticulitis (AUD) neither accelerate recovery nor prevent complications or recurrences. A retrospective cohort study was conducted, including all consecutive AUD patients hospitalized 2015- 2018 at Helsingborg Hospital (HH) and Skåne University (SUS), Sweden. HH had implemented a non-antibiotic treatment protocol 2014 while SUS not. Main outcomes were proportion of treated with...
Abstract Aim Stage III colon cancer is routinely treated with adjuvant chemotherapy, which causes significant short‐term morbidity. Its effect on long‐term quality of life (QoL) poorly investigated. The aim this study was to investigate QoL after curative treatment for and explore the impact chemotherapy general disease‐specific QoL. Method All patients aged under 75 years operated between 30 September 2007 1 October 2019 were identified by Cancer Registry Norway. Exclusion criteria distant...
Abstract Background Radiotherapy reduces local recurrence in locally advanced rectal cancer, but may cause harm patients who do not experience recurrence. The aim was to investigate the impact of radiotherapy on long-term quality life after curative treatment for i.e. without a during follow-up. Methods All operated cancer Norway under 75 years age between 30 September 2007 and 1 October 2020 were identified using Cancer Registry Norway. Exclusion criteria distant metastasis, dementia....
Routine antibiotic treatment of acute uncomplicated diverticulitis (AUD) has been shown ineffective. In this study, the adherence to a new protocol for was evaluated and incidence complications in patients treated with without antibiotics investigated.A retrospective study in-patients diagnosed AUD at Helsingborg Hospital, Sweden between 01 January 2013 06 2015 performed. Antibiotics were routinely administrated until May 2014. Thereafter, antibiotic-free introduced. All followed regarding...
Abstract Background The Scandinavian Diverticulitis (SCANDIV) trial and the LOLA arm of LADIES randomized patients with Hinchey III perforated diverticulitis to laparoscopic peritoneal lavage or sigmoid resection. aim this analysis was identify risk factors for treatment failure in diverticulitis. Methods This a post hoc SCANDIV arm. Treatment defined as morbidity requiring general anaesthesia (Clavien–Dindo grade IIIb higher) within 90 days. Age, sex, BMI, ASA fitness grade, smoking status,...
Throughout the last century, incidence of diverticular disease colon has increased tremendously in industrialized countries; nevertheless, management this condition is still controversial. Although several international guidelines for are based on same evidence, recommendations differ greatly, emphasizing lack high-quality prospective studies. In Scandinavia, official exist only Denmark. However, treatment policies quite similar all Scandinavian countries. Computed tomography first choice...