A5100766017- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Circular RNAs in diseases
- Topological Materials and Phenomena
- Rare-earth and actinide compounds
- RNA modifications and cancer
- Magnetic and transport properties of perovskites and related materials
- Magnetic Properties of Alloys
- Biochemical effects in animals
- Metabolism and Genetic Disorders
- Biofuel production and bioconversion
- Iron-based superconductors research
- Heusler alloys: electronic and magnetic properties
- Protease and Inhibitor Mechanisms
- 2D Materials and Applications
- Metal complexes synthesis and properties
- Mitochondrial Function and Pathology
- Free Radicals and Antioxidants
- TGF-β signaling in diseases
- Oral microbiology and periodontitis research
- Advanced Condensed Matter Physics
- Magnetism in coordination complexes
- Electrochemical sensors and biosensors
- Conducting polymers and applications
- RNA Research and Splicing
University of Science and Technology of China
2022-2024
High Magnetic Field Laboratory
2022-2024
Chinese Academy of Sciences
2022-2024
Tianjin Medical University
2024
Tianjin First Center Hospital
2024
Chongqing University
2024
Hefei Institutes of Physical Science
2022-2024
Anhui University
2022
Fourth Hospital of Changsha
2022
Hunan Normal University
2022
Triple-negative breast cancer (TNBC) harbors genetic heterogeneity and generally has more aggressive clinical outcomes. As such, there is urgency in identifying new prognostic targets developing novel therapeutic strategies. In this study, miR-224 was overexpressed cell lines TNBC primary samples. Knockdown of MDA-MB-231 cells reduced proliferation, migration, invasion. Through integrating silico prediction algorithms with KEGG pathway Gene Ontology analyses, CASP9 identified to be a...
Understanding the mechanisms for forming skyrmionic spin configurations at room temperature is essential exploring applicable spintronics devices based on topological textures. In this work, anisotropic magnetic properties and critical behavior are investigated in noncollinear itinerant magnet PrMn2Ge2. The strongly interactions field induced antiferromagnetic to ferromagnetic transition observed. of high 331 K was analyzed, exponents β = 0.335, γ 0.878, δ 3.617 extracted by modified Arrott...
Objective: This research probed into the molecular mechanisms of long non-coding RNA (lncRNA) VPS9D1 Antisense 1 (VPS9D1-AS1) in lung adenocarcinoma (LUAD). Methods: lncRNA expression level was evaluated bioinformatically, and its downstream miRNA/mRNA regulatory axis predicted by bioinformatics methods as well. qRT-PCR used to measure VPS9D1-AS1, miRNA-30a-5p, kinesin family member 11 (KIF11) expression. Western blot performed KIF11 protein Proliferation, migration, invasion LUAD cells were...
The combination of topology and magnetism has demonstrated great potential in the search emergent quantum matters. In this study, we report synthesis, magnetic, electrical properties GdAuPb, a rare-earth-based half-Heusler topological antiferromagnet candidate. Magnetization specific heat studies reveal highly frustrated antiferromagnetic ordering Gd at TN = 11.5 K. Interestingly, material possesses large, unsaturated magnetoresistance up to 800% below anomalous Hall conductivity as large...
We report the magnetic, thermodynamic, and electrical properties of ${\mathrm{EuRh}}_{2}{\mathrm{Al}}_{8}$, a Eu-based heavy fermion member in ${\mathrm{RT}}_{2}{\mathrm{X}}_{8}$ families with an orthorhombic $Pbam$ structure. Magnetization studies reveal multiple phase transitions single crystals, including two successive antiferromagnetic at ${T}_{N1}\ensuremath{\sim}12.5\phantom{\rule{0.16em}{0ex}}\mathrm{K}$ ${T}_{N2}\ensuremath{\sim}8.2\phantom{\rule{0.16em}{0ex}}\mathrm{K}$. These are...
The β-L-arabinofuranosidase (HypBA1) from Bifidobacterium longum JCM 1217 hydrolyzes the β-1,2-linked arabinofuranose disaccharide to release L-arabinoses. HypBA1 was classified into glycoside hydrolase family 127 (GH127) by CAZy website (http://www.cazy.org/). enzyme expressed in Escherichia coli and purified recombinant protein crystallized. Crystals belonging primitive hexagonal space group P 3 x 21, with unit-cell parameters a = b 75.9, c 254.0 Å, were obtained sitting-drop...
Abstract Background Breast cancer is a heterogeneous malignant disease, which has variation in clinical behaviors. High‐throughput technologies have added important genetic alternative and biological change information for breast cancer. CARNS1 an ATPases. It can catalyze the synthesis of carnosine, antiproliferative activity Here, we hypothesize that plays essential role development Methods The expressions were data‐mined analyzed from TCGA (the Cancer Genome Atlas) GEO Gene Expression...
It has been proven that miR-133b could inhibit cancer cell growth, the expression level of was significant reduction in lung tissue and serum patients, increase radiation sensitivity squamous carcinoma by targeting PKM2, but exist mechanisms is not clear. The aim this study to explore effect on proliferation A549 stem cells drug DDP, relationship between PKM2 gene, as well cells.Using miRBase miRNAMap database sequence comparison gene. Using immune magnetic separation method select...
Human periodontal ligament stem cells (hPDLSCs) play a critical role in the regeneration of tissue. Forkhead box protein A1 (FOXA1) has been implicated inflammatory mechanisms various diseases. However, FOXA1 inflammation and its effect on osteogenic differentiation hPDLSCs remains unclear. In this study, healthy tooth root-derived were isolated, flow cytometry was used to detect cell surface markers. Western blot immunofluorescence analyses performed assess levels different tissues. The...
Kagome materials have recently drawn great attention due to the interplay between nontrivial band topology, electron correlations, and Van Hove singularities related many-body orders. Here we report three new vanadium-based kagome metals, TiV6Sn6, ZrV6Sn6, HfV6Sn6, conduct a comprehensive investigation of their structural, magnetic, electrical transport properties. All compounds exhibit large unsaturated magnetoresistances multiband Hall effects at low temperatures, indicating existence...