A5026586400- Nanocluster Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Nanoparticle-Based Drug Delivery
- Gold and Silver Nanoparticles Synthesis and Applications
- Ferrocene Chemistry and Applications
- Dendrimers and Hyperbranched Polymers
- Graphene and Nanomaterials Applications
- Autophagy in Disease and Therapy
- Advanced Cellulose Research Studies
- Extracellular vesicles in disease
- ZnO doping and properties
- TiO2 Photocatalysis and Solar Cells
- Adsorption and biosorption for pollutant removal
- Pickering emulsions and particle stabilization
- Advanced biosensing and bioanalysis techniques
- Metal complexes synthesis and properties
- Nanoplatforms for cancer theranostics
- Advanced Photocatalysis Techniques
Zhongyuan University of Technology
2019-2024
Platinum (Pt)-based chemotherapy drugs such as cisplatin are the first line and core options for treatment of ovarian cancer (OC), while resistance has a worse prognosis low 5 year survival rate patients. Chemotherapeutic synthesized from nanomaterials have shown great potential in biomedicine; however, research into their application OC is rarely discussed. This study proposed to elucidate anti-tumor effects polyethylenimine (PEI)-caged platinum nanoclusters (Pt NCs) on cisplatin-resistant...
Noble metal nanoclusters (M NCs), defined as an aggregation of a few to tens atoms, are considered borderline between atoms and nanoparticles NPs), which tends exhibit molecule-like behaviours such discrete electronic state size-dependent fluorescence. In the past decades, gold silver (Au NCs Ag NCs) have been massively explored utilized in field industrial catalysis, optoelectronic devices, biological imaging, environmental detection, clinical diagnoses, treatment. The analogue Au platinum...
In recent years, multifunctional platinum nanoclusters (Pt-NCs) as new Pt-based anti-cancer drugs exhibit a promising therapeutic efficiency for several cancer diseases, especially human pulmonary carcinoma. However, the endocytosis behaviors (like uptake pathway, etc.) and induced apoptosis mechanism of Pt-NCs drug-resistant non-small cell lung (NSCLC), are still inconclusive. this research, we explored endocytic pathway in both typical NSCLC A549 cells cisplatin-resistant A549/Cis through...
Lung cancer is the leading cause of deaths worldwide and most patients receiving conventional chemotherapy suffer from severe side effects due to non-selective chemotherapeutic drugs on normal cells. Targeted nanomaterials can obtain excellent accumulation at tumor site through their active or passive targeting mechanisms, thereby reducing toxicity in various ways. In this study, hyaluronic acid (HA) which could specifically bind CD44 surface cells, was used modify amine-caged platinum...
The effluent discharge produced in the textile printing and dyeing, leather other fields, will cause irreversible environmental pollution extremely threatening safety of living organisms. appropriate efficient disposal method dyestuff originated wastewater has been widely concerned past decades. In this study, recrystallization 1,3,5-benzene tricarboxylic acid (RCTMA) was put forward via a hydrothermal to form supramolecular RCTMA-based hexamer thereafter assembled into porous nano-bacterial...
In the past few years, platinum nanomaterials (Pt NMs) have gained attraction owing to their ability address drawbacks of classical Pt-based chemotherapy drugs including drug resistance and clinical side effects, which been preliminarily used in lung cancer, liver gynecological etc. order investigate effect Pt NMs on hematopoietic tumors, ultra-small nanoclusters NCs) were employed clarify targeting recognition, cellular uptake, effective therapy vivo for chronic myeloid leukemia (CML)...