Lingyun Zhao

ORCID: 0000-0002-2551-2999
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Research Areas
  • Advanced MRI Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • MRI in cancer diagnosis
  • Radiomics and Machine Learning in Medical Imaging
  • Glioma Diagnosis and Treatment
  • Nanocluster Synthesis and Applications
  • Lanthanide and Transition Metal Complexes
  • COVID-19 Clinical Research Studies
  • Advanced biosensing and bioanalysis techniques
  • COVID-19 diagnosis using AI
  • Magnetism in coordination complexes
  • Medical Imaging Techniques and Applications
  • Functional Brain Connectivity Studies
  • Advanced Nanomaterials in Catalysis
  • Family Support in Illness
  • Cancer Mechanisms and Therapy
  • Concrete and Cement Materials Research
  • Liver physiology and pathology
  • Coal Properties and Utilization
  • Magnesium Oxide Properties and Applications
  • COVID-19 and healthcare impacts
  • Luminescence and Fluorescent Materials
  • Dendrimers and Hyperbranched Polymers
  • Bone Tissue Engineering Materials
  • Neurological and metabolic disorders

Guizhou University
2025

Ministry of Natural Resources
2023-2025

Huazhong University of Science and Technology
2013-2024

Research Institute of Petroleum Exploration and Development
2023

Tongji Hospital
2011-2022

Henan Provincial People's Hospital
2022

Zhengzhou University
2022

Fifth Affiliated Hospital of Zhengzhou University
2021

Qufu Normal University
2018

Zero to Three
2016

In late December 2019, an outbreak of coronavirus disease (COVID-19) in Wuhan, China was caused by a novel coronavirus, newly named severe acute respiratory syndrome 2. We aimed to quantify the severity COVID-19 infection on high-resolution chest computed tomography (CT) and determine its relationship with clinical parameters.From January 11, 2020, February 5, clinical, laboratory, CT features 42 patients (26-75 years, 25 males) were analyzed. The initial follow-up CT, obtained mean 4.5 days...

10.1097/rli.0000000000000674 article EN Investigative Radiology 2020-03-05

// Rifeng Jiang 1, * , Jingjing Lingyun Zhao 1 Jiaxuan Zhang Shun Yihao Yao Shiqi Yang Shi Nanxi Shen Changliang Su Ju Wenzhen Zhu Department of Radiology, Tongji Hospital, Medical College, Huazhong University Science and Technology, Wuhan, China These authors have contributed equally to this work Correspondence to: Zhu, e-mail: zhuwenzhen@hotmail.com Keywords: diffusion kurtosis imaging, glioma, grading, cellular proliferation, Ki-67 Received: April 29, 2015     ...

10.18632/oncotarget.5675 article EN Oncotarget 2015-11-03

Purpose To determine the utility of intravoxel incoherent motion (IVIM) imaging in grading gliomas and compare IVIM perfusion metrics with arterial spin labeling (ASL)‐derived cerebral blood flow (CBF). Materials Methods Fifty‐two patients pathologically confirmed underwent ASL at 3.0T. perfusion‐related diffusivity (D*), fraction (f), product f D*(f×D*), true (D), apparent diffusion coefficient (ADC) were obtained to distinguish glioma grades. The CBF derived from pseudocontinuous within...

10.1002/jmri.25191 article EN Journal of Magnetic Resonance Imaging 2016-02-16

Injecting carbon dioxide (CO2) into coal seams enhances coalbed methane (CBM) recovery and promotes the CO2 geological sequestration. In this process, reservoir temperature plays a crucial role in interaction between coal. However, microstructural changes of at different saturation temperatures under subcritical (Sub CO2) conditions remain unclear. This study used scanning electron microscopy (SEM), low-temperature N2 adsorption, Fourier transform infrared spectroscopy (FTIR) to analyze...

10.1021/acs.energyfuels.4c05258 article EN Energy & Fuels 2025-01-13

<h3>BACKGROUND AND PURPOSE:</h3> Prognosis in glioma depends strongly on tumor grade and proliferation. In this prospective study of patients with untreated primary cerebral gliomas, we investigated whether amide proton transfer–weighted imaging could reveal proliferation reliably distinguish low-grade from high-grade gliomas compared Ki-67 expression MR spectroscopy imaging. <h3>MATERIALS METHODS:</h3> This included 42 (<i>n</i> = 28) or 14) glioma, all whom underwent conventional imaging,...

10.3174/ajnr.a5301 article EN cc-by American Journal of Neuroradiology 2017-07-20

Various regularization methods have been proposed for single-orientation quantitative susceptibility mapping (QSM), which is an ill-posed magnetic field to source inverse problem. Noise amplification, a major issue in problems, manifests as streaking artifacts and quantification errors QSM has not comparatively evaluated these algorithms. In this paper, various were systematically categorized noise analysis. Six representative selected from four categories: two non-Bayesian with alteration...

10.1109/tbme.2013.2266795 article EN IEEE Transactions on Biomedical Engineering 2013-06-07

Self-assembled nanospheres are fabricated by silicon nanoparticles and Au nanoclusters for the ratiometric detection of Zn<sup>2+</sup> applied in cell imaging.

10.1039/c8tb01046c article EN Journal of Materials Chemistry B 2018-01-01

Magnesium oxychloride cement (MOC) possesses some excellent characteristics, which can be used as oil well cement, to deal with the complex environmental conditions in and gas wells. However, water resistance property of MOC is poor. In this study, a new type magnesium improved was developed by modifying pore structure pure using hydrophobic admixtures. To assess performance MOC, range tests were performed, including compressive strength, softening coefficient, capillary absorption, size...

10.1016/j.conbuildmat.2023.133745 article EN cc-by Construction and Building Materials 2023-10-23

In recent years, multifunctional platinum nanoclusters (Pt-NCs) as new Pt-based anti-cancer drugs exhibit a promising therapeutic efficiency for several cancer diseases, especially human pulmonary carcinoma. However, the endocytosis behaviors (like uptake pathway, etc.) and induced apoptosis mechanism of Pt-NCs drug-resistant non-small cell lung (NSCLC), are still inconclusive. this research, we explored endocytic pathway in both typical NSCLC A549 cells cisplatin-resistant A549/Cis through...

10.1016/j.biopha.2021.112360 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2021-10-28

Lung cancer is the leading cause of deaths worldwide and most patients receiving conventional chemotherapy suffer from severe side effects due to non-selective chemotherapeutic drugs on normal cells. Targeted nanomaterials can obtain excellent accumulation at tumor site through their active or passive targeting mechanisms, thereby reducing toxicity in various ways. In this study, hyaluronic acid (HA) which could specifically bind CD44 surface cells, was used modify amine-caged platinum...

10.1002/open.202100070 article EN ChemistryOpen 2021-08-06

10.1109/robio64047.2024.10907454 article EN 2021 IEEE International Conference on Robotics and Biomimetics (ROBIO) 2024-12-10

Objective To explore the application of amide proton transfer (APT) imaging in differentiating glioma from treatment effect and to evaluate diagnostic efficiency quantitative APT-related parameters. Methods A total 23 patients (15 males, 8 females, age: 13-80 years) with 27 lesions who had underwent APT Tongji Hospital(Wuhan, China) October 2014 June 2015 were enrolled this prospective study. The scan protocols MRI normal plain scanning, diffusion WI, contrast-enhancement T1WI...

10.3760/cma.j.issn.2095-2848.2017.06.004 article EN Zhonghua heyixue yu fenzi yingxiang zazhi 2017-06-25
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