A5101504192- Neonatal Respiratory Health Research
- COVID-19 Clinical Research Studies
- Advanced Radiotherapy Techniques
- Cancer-related molecular mechanisms research
- Head and Neck Cancer Studies
- Social Acceptance of Renewable Energy
- Lung Cancer Research Studies
- Environmental Impact and Sustainability
- COVID-19 diagnosis using AI
- Parasitic Infections and Diagnostics
- Antimicrobial Peptides and Activities
- Cystic Fibrosis Research Advances
- Acne and Rosacea Treatments and Effects
- Kawasaki Disease and Coronary Complications
- Medical Research and Treatments
- Cardiac Ischemia and Reperfusion
- Endometrial and Cervical Cancer Treatments
- Signaling Pathways in Disease
- Dermatologic Treatments and Research
- melanin and skin pigmentation
- Breast Cancer Treatment Studies
- COVID-19 and healthcare impacts
- China's Ethnic Minorities and Relations
- Hearing, Cochlea, Tinnitus, Genetics
- Sepsis Diagnosis and Treatment
Huazhong University of Science and Technology
2007-2024
Central Hospital of Wuhan
2018-2024
Union Hospital
2021
The Fourth People's Hospital
2021
Sichuan University
2018-2020
Tongji Hospital
2020
Jiangxi Provincial People's Hospital
2019
Kunming Medical University
2017
First Affiliated Hospital of Kunming Medical University
2017
China-Japan Friendship Hospital
2015
In late December 2019, an outbreak of coronavirus disease (COVID-19) in Wuhan, China was caused by a novel coronavirus, newly named severe acute respiratory syndrome 2. We aimed to quantify the severity COVID-19 infection on high-resolution chest computed tomography (CT) and determine its relationship with clinical parameters.From January 11, 2020, February 5, clinical, laboratory, CT features 42 patients (26-75 years, 25 males) were analyzed. The initial follow-up CT, obtained mean 4.5 days...
Abstract Background The serum surfactant protein D (SP-D) level is suggested to be a useful biomarker for acute lung injuries and respiratory distress syndrome. Whether the SP-D could identify severity of coronavirus disease 2019 (COVID-19) in early stage has not been elucidated. Methods We performed an observational study on 39 laboratory-confirmed COVID-19 patients from Fourth People’s Hospital Yiyang, Hunan, China. Receiver operating characteristic (ROC) curve analysis, correlation...
Whilst radiotherapy (RT) is widely used for cancer treatment, radiodermatitis caused by RT one most common severe side effect affecting 95% patients. Accurate assessment and classification essential to adopt timely management monitoring, which all depend on reliable objective tools grading. We therefore, in this work, reported the development grading performance validation of a low-cost (∼2318.2 CNY) algorithms-based hyperspectral imaging (aHSI) system assessment. The aHSI was enabled...
This study aimed to investigate the immunoprotection of recombinant Eg.myophilin (rEg.myophilin) and tentatively analyze mechanism this protection.Three groups female mice were immunized subcutaneously with rEg.myophilin contrasts, after two boosters, challenged Eg protoscoleces (PSCs) intraperitoneally, then analyzed humoral immune response specific IgG, IgG1, IgG2a, IgG2b, IgG3 IgE, also evaluated cellular IFN-γ, IL-4, IL-10.Mice produced effective immunity protection (reductions in cyst...
Abstract Background and purpose Cardiovascular risk burden in midlife has been linked to cognitive decline later life, but whether this association still exists older cohorts is unclear. Methods The between the cardiovascular score function was investigated using 9‐year follow‐up data. algorithms were from Chinese guidelines on prevention treatment of dyslipidemia adults (2016 revised), which assessed at baseline categorized into tertiles (low, middle high). Full intelligence quotient (FIQ),...
To evaluate the efficacy and toxicity of two IC (induction chemotherapy) regimens, TPF (taxanes, cisplatin, 5-fluorouracil) TP (taxanes cisplatin) combined with concurrent chemoradiotherapy (CCRT) in locally advanced nasopharyngeal carcinoma (LA-NPC) patients.Ultimately, we enrolled 213 patients at stage III-IVA this retrospective study. The prognosis was compared by Kaplan-Meier Cox proportional hazard regression. toxicities were evaluated according to CTCAE v4.0 RTOG criteria.TPF found...
This study investigated the factors affecting surgical treatment effect on patients with laryngeal cancer. The clinical data (including sex, age, smoking index, drinking, primary tumor site, (T) stage, lymph nodes (N) differentiation degree, diameter, method, node metastasis and cervical dissection) of 215 cancer in Central Hospital Wuhan were analyzed retrospectively; survival rate was calculated using Kaplan-Meier method; log-rank test used for single-factor analysis, while Cox...
Background: Hearing loss (HL) is the most common disorder in newborns with a highly heterogeneous genetic background. Despite significant progress screening and identifying genes related to congenital hearing loss, there are still candidate implicated HL that remain undiscovered. Methods: We investigated 43 Chinese families by segregating bilateral sensorineural via whole-exome sequencing (WES) Sanger sequencing. Results: Variants were found 10 known non-syndromic (NSHL) genes, 5 syndromic...
Objective To evaluate and compare the clinical efficacy safety of intense pulsed light (IPL) versus 595-nm dye laser (PDL) for treatment post-acne erythema. Methods A randomized split-face trial was conducted. A total 20 patients with erythema were enrolled, to receive IPL on one half face PDL other facial side once every 4 weeks 3 sessions. Digital photographs taken using VISIA, index recorded before each month after last treatment. The severity bilateral evaluated based a 4-point...
Purpose: The clinical application of lung SBRT requires extremely accurate targeting during treatment since its dose regimen is so potent. Although abdominal compression may be used to reduce respiratory motion, tumor motion not eliminated entirely and it still necessary evaluate the delivered target treatment. This study was designed explore a framework for tracking using daily CBCT data. Method Materials: Ten patients were this study. GTV-PTV margins 5 mm. prescription 20 Gy per fraction...
Objective To investigate and evaluate the comprehensive ability current situation of health care services for climacteric women medical institutions in Sichuan Province, so as to provide guidance further improvement women. Methods A total 193 physicians who attended continuing education projects held by West China Second University Hospital, Provincial Hospital Women Children from November 2016 June 2017, 121 hospitals where all these worked at were selected research subjects. The...
Objective To analyze the levels of cytokines (IL-2,IFN-γ,IL-6,IL-10) associated with Th1 and Th2 cells in HLA-DQ8 transgenic mice model ocular experimental autoimmune myasthenia gravis (oEAMG) induced by recombinant H-AChR γ subunit immunization.Methods DQ8 were immunized 20 μg AChR subunit,20 crude E. coli extract (E. group),or complete Freund's adjuvant (CFA) only (CFA group). All on days 0,30,and 60. Mice euthanized 28 after third immunization,and draining lymph node (LNC) spleen...