Л. Л. Берштейн

ORCID: 0000-0002-9444-159X
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About
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Coronary Interventions and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Function and Risk Factors
  • Cardiovascular Health and Disease Prevention
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cerebrovascular and Carotid Artery Diseases
  • Lipoproteins and Cardiovascular Health
  • Healthcare Systems and Public Health
  • Cardiovascular Disease and Adiposity
  • Ultrasound in Clinical Applications
  • Medical Research and Treatments
  • Marine and Coastal Research
  • Heart Failure Treatment and Management
  • Technology and Data Analysis
  • Venous Thromboembolism Diagnosis and Management
  • Advanced MRI Techniques and Applications
  • Cardiovascular and exercise physiology
  • Radiation Dose and Imaging
  • Cardiac Health and Mental Health
  • Peripheral Artery Disease Management
  • Neurological Disorders and Treatments

North-Western State Medical University named after I.I. Mechnikov
2016-2025

Ischemia with no obstructive coronary artery disease (INOCA) is common and has an adverse prognosis. We set out to describe the natural history of symptoms ischemia in INOCA.CIAO-ISCHEMIA (Changes Angina over One Year ISCHEMIA Trial Screen Failures With INOCA) was international cohort study conducted from 2014 2019 involving angina assessments (Seattle Questionnaire) stress echocardiograms 1 year apart. This ancillary that included patients a who were not randomly assigned trial....

10.1161/circulationaha.120.046791 article EN Circulation 2021-06-01

Due to the routine use of endovascular revascularization and improved medical therapy, majority acute coronary syndrome (ACS) cases now have an uncomplicated course. However, in spite currently accepted secondary prevention standards, residual risk remote major adverse cardiovascular events (MACEs) after ACS remains high. Ultrasound carotid/subclavian atherosclerotic plaque assessment may represent alternative approach estimate MACE control quality prevention. Aim: To find most important...

10.3390/life15030431 article EN cc-by Life 2025-03-09

Стандартные протоколы ультразвукового исследования включают всех сосудов анализируемой области, во режимах сканирования, с полным набором измерений, и требуют высокой квалификации специалистов больших временных затрат. Однако для ряда клинических задач достаточно выполнения фокусированного протокола исследования, т.е. ориентированного на решение конкретной проблемы и, следовательно, сокращенного по времени, тем самым позволяющего увеличить число обследуемых. Оценка сердечно-сосудистого риска...

10.15829/1728-8800-2022-3333 article RU cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2022-06-20

Aim. To characterize the association between cardiovascular risk factors and clinical paraclinical variables with severity of concomitant carotid subclavian atherosclerosis in patients acute coronary syndrome (ACS). Material methods. Patients ACS any type, having obstructive artery disease (CAD) confirmed by angiography, underwent an ultrasound arteries quantitative plaque assessment. The most important clinical, echocardiographic, angiographic laboratory that contribute to and/or affect...

10.15829/1728-8800-2024-4005 article EN cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2024-07-07

Background: Patients with significant (≥50%) left main disease (LMD) have a high risk of cardiovascular events, and guidelines recommend revascularization to improve survival. However, the impact intermediate LMD (stenosis, 25%–49%) on outcomes is unclear. Methods: Randomized ISCHEMIA (International Study Comparative Health Effectiveness With Medical Invasive Approaches) participants who underwent coronary computed tomography angiography at baseline were categorized into those (25%–49%)...

10.1161/circinterventions.121.010925 article EN Circulation Cardiovascular Interventions 2022-04-01

Aim Analysis of inter- and intra-study variability changes in the atherosclerotic plaque (ASP) total height area, main quantitative indexes that were planned to be used present study for assessment load carotid arteries.Material methods The incidence recurrent cardiovascular complications (CVC) within 1 year after acute coronary syndrome (ACS) ranges from 7-9 % (in studies) 34 clinical practice). This indicates insufficient efficacy traditional approaches secondary prevention heart disease....

10.18087/cardio.2023.9.n2460 article EN cc-by Kardiologiia 2023-09-30

Aim. To compare the accuracy of predicting risk fatal and non-fatal cardiovascular events (CVE) based on SCORE scaling ultrasound imaging carotid atherosclerotic plaque (AP) in patients without manifested disease (ACVD) a multidisciplinary hospital. Material methods. We examined 841 (353 men) (avearage age 54,9±8), with at least 1 traditional factor ACVD. Ultrasound examination arteries was performed all patients. Patients nonstenotic AP constituted AP+ group, — AP-group (356 485 people,...

10.15829/1560-4071-2019-5-20-25 article EN cc-by Russian Journal of Cardiology 2019-06-14

Despite a significant progress of the recent decades, incidence cardiovascular complications in patients with manifest, stable ischemic heart disease (IHD) is still high. Furthermore, this patient group heterogenous; individuals higher risk can be isolated from based on presence comorbidities and acute IHD background therapy. Such require more aggressive treatment to influence major components increased risk. Even after administration an optimum therapy, for such remains high (residual...

10.18087/cardio.2020.11.n1370 article EN cc-by Kardiologiia 2020-12-03

Coronary revascularization is one of the most studied treatment modalities in cardiology, however, there no consensus among experts about its indications patients with stable coronary artery disease (SCAD). Contemporary data regarding role SCAD are clear conflict current European guidelines. This article discusses main statements significant American and Guidelines on myocardial last decade, also analyzes appropriateness to improve prognosis symptoms CCS light new research data, primarily...

10.20944/preprints202306.0567.v1 preprint EN 2023-06-08

Although myocardial revascularization is one of the most studied types medical interventions, there a heated discussion in cardiology about feasibility and indications for it patients with stable coronary artery disease (chronic syndrome). The recently completed ISCHEMIA trial largest current study comparing conservative versus invasive strategies this category patients. article discusses rationale to improve prognosis according trial.

10.15829/1560-4071-2020-3819 article EN cc-by Russian Journal of Cardiology 2020-09-14

Aim . To study the associations between risk factors, clinical characteristics, severity of brachiocephalic artery (BCA) atherosclerosis and coronary (CA) disease in patients with acute syndrome (ACS). Material methods The included any type ACS obstructive confirmed by angiography. A quantitative analysis angiography data was performed an assessment number CAs significant stenosis calculation SYNTAX score. major laboratory parameters that are factors for and/or affect cardiovascular...

10.18087/cardio.2024.12.n2686 article EN Kardiologiia 2024-12-25

Coronary revascularization is one of the most studied types interventions in cardiology, but there no consensus among specialists about indications for its implementation patients with chronic coronary syndromes (CCS). The data recently completed clinical trials on role CCS clearly contradict current Guidelines, emphasizing high effectiveness modern conservative therapy. This paper discusses main recommendations significant American and European Guidelines myocardial revascularization, also...

10.20996/1819-6446-2021-10-02 article EN cc-by Rational Pharmacotherapy in Cardiology 2021-11-03

High morbidity and mortality from ischemic heart disease (CHD) in RF presupposes the significance of individual prognosis cardiovascular risk primary prevention. Aim. To analyze level that could be calculated patients with CHD debut just before manifest therefore to evaluate opportunities for by standard scores; relation a real volume prevention events current Guidelines. Material methods. In 122 hospitalized as an acute coronary syndrome, retrospective evaluation, which found onset disease....

10.15829/1728-8800-2014-6-38-43 article EN cc-by CARDIOVASCULAR THERAPY AND PREVENTION 2014-12-28

The assessment of reperfusion effectiveness in acute myocardial infarction (AMI) is an important clinical task. In 106 AMI patients with ST elevation, the dynamics segment and Twave was analyzed using data three electrocardiograms (baseline, 3 48 hours after thrombolysis - ECG-1, 2, 3, respectively). Separately for anterior поп-anterior AMI, decrease degree lead its maximal elevation (STmax aAMI, naAMI), as well total all leads (STsum naAMI) were analyzed. Other parameters calculated...

10.15829/1560-4071-2007-6-37-41 article EN Российский кардиологический журнал 2007-12-28

Atherosclerotic cardiovascular disease is the leading cause of death in world, primarily low-and middle-income countries, including Russian Federation. According to WHO experts, global atherosclerotic epidemic can be brought under control mainly by improving prevention. This paper describes modern principles risk assessment people without manifested disease, as well considers drug and non-drug methods primary

10.17816/mechnikov75696 article EN HERALD of North-Western State Medical University named after I I Mechnikov 2021-08-30
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