Nitin Ghoshal

ORCID: 0000-0002-9448-4717
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About
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Research Areas
  • NF-κB Signaling Pathways
  • Phytochemicals and Antioxidant Activities
  • Tannin, Tannase and Anticancer Activities
  • DNA Repair Mechanisms
  • Arsenic contamination and mitigation
  • Polyomavirus and related diseases
  • Glutathione Transferases and Polymorphisms
  • Carcinogens and Genotoxicity Assessment
  • Cancer, Hypoxia, and Metabolism
  • Genetic factors in colorectal cancer
  • Fluoride Effects and Removal
  • Oral Health Pathology and Treatment
  • Agriculture and Biological Studies
  • Biological Activity of Diterpenoids and Biflavonoids

North Eastern Hill University
2012-2016

Abstract Potentilla fulgens has been used for a long time as folk remedy variety of ailments without having information on its pharmacological action. The study was intended to determine the effectiveness in antitumor activity among kaempferol (KMP) flavonoids, ellagic acid (ELA) polyphenols and methanolic extract root P. (PRE) Ehrlich ascites tumour (EA) MCF-7 cancer cells. total phenolic flavonoid content were found be 138.8 ± 1.6 mg gallic 401.6 4.6 quercetin per 1 gm extract,...

10.1515/1553-3840.1644 article EN Journal of Complementary and Integrative Medicine 2012-09-24

Fluoride is an essential trace element but also environmental contaminant with major sources of exposure being drinking water, food and pesticides. Previous studies showed that sodium fluoride (NaF) at 5 mM or more required to induce apoptosis chromosome aberrations proposed DNA damage play important role in toxicity excessive fluoride. The aim this study directed understand the nature DNA-lesions induced by NaF allowing its interaction radiation DNA-lesions. was used after observing...

10.1016/j.toxrep.2015.02.001 article EN cc-by-nc-nd Toxicology Reports 2015-01-01

Abstract Background There are strong indications for a causal association between areca-nut consumption and cancers. In Meghalaya, India, the variety of is used as raw unprocessed form whose chemical composition pharmacological actions have been reported. Yet we know little on initial pathway involved in associated carcinogenesis since it difficult to assess its effects genetic alterations without interference other compounding factors. Therefore, present study was undertaken mice verify...

10.1186/1471-2407-13-315 article EN cc-by BMC Cancer 2013-06-28
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