- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
- Science and Science Education
- Ophthalmology and Eye Disorders
- Retinal Diseases and Treatments
- Ocular Disorders and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Business and Management Studies
- Maternal and Neonatal Healthcare
- Retinal Imaging and Analysis
- Ocular Diseases and Behçet’s Syndrome
- Retinal and Optic Conditions
- Public Health in Brazil
- Retinal and Macular Surgery
- Education and Public Policy
- Traumatic Ocular and Foreign Body Injuries
- Herpesvirus Infections and Treatments
- Galectins and Cancer Biology
- Ocular and Laser Science Research
- Health Education and Validation
Universidade Federal de São Paulo
2016-2025
Instituto de Olhos de Goiânia
2021-2024
Creative Commons
2023
Hospital São Paulo
2022
Advanced Neural Dynamics (United States)
2022
Universidade de Sorocaba
2017
Instituto Penido Burnier
2017
Instituto da Visão
2004-2016
Christie's
2015
National Academies of Sciences, Engineering, and Medicine
2015
Abstract Background Postoperative endophthalmitis (PSE) is a severe ocular complication that can lead to irreversible vision loss or even globe atrophy. The Endophthalmitis Vitrectomy Study (EVS) historically guided PSE management but increasingly questioned due advances in pars plana vitrectomy (PPV) techniques and its narrow focus on cataract surgery. This study aimed compare PPV followed by intravitreal antibiotic injection at the end of surgery (PPV + IVAIES) with alone (IVAI) managing...
ABSTRACT PURPOSE: lntrastromal Ferrara ring segments were inserted in eyes with severe keratoconus to evaluate safety and efficacy of this procedure. METHODS: placed 36 35 patients keratoconus, who evaluated after 12 months follow-up. All had highly disabling visual acuity, contact lens intolerance, a previous indication for penetrating keratoplasty. Statistical analysis included preoperative postoperative uncorrected best spectacle-corrected manifest refraction, anterior chamber depth,...
Autologous serum has been used to treat dry eye syndrome for many years. It contains several growth factors, vitamins, fibronectin and other components that have considered important corneal conjunctival integrity. Serum drops are usually prepared as an unpreserved blood solution. The is by nature well tolerated its biochemical properties somewhat similar natural tears. reported be effective the treatment of severe eye-related ocular surface disorders (Sjögren's syndrome), also entities such...
<h3>Purpose:</h3> To evaluate the response of stromal keratocytes to central corneal deepithelialization. <h3>Methods:</h3> Rabbits and monkeys underwent unilateral mechanical deepithelialization with a blunt instrument were killed at intervals ranging from 15 minutes 24 hours after surgery. Two rabbits under fluid bath containing preservation medium. treated unilaterally medium topically applied every for 16 epithelial removal. Four linear keratotomy immediately cornea or on normal...
Background Species of the genus Acanthamoeba spp. are ubiquitous and can cause keratitis (AK), a serious corneal infection. Due to toxicity ineffectiveness currently available prolonged therapies, we investigated electroceutical treatment aimed at facilitating permeation molecules through membrane cysts trophozoites, which allows for faster elimination parasite. Methods Cysts trophozoites polyphaga (ATCC® 30461 TM ) were exposed in vitro an electric field with intensities 2,000 volts 2,500...
To report risk factors, clinical course, and outcome in patients with infectious keratitis following implantation of intracorneal ring segments (ICRS).The records 8 culture-proven after ICRS (Ferrara or Intacs) were retrospectively reviewed. Age, gender, corneal findings, ocular abnormalities, the condition that led to implantation, immediate prior use a contact lens, elapsed time between onset symptoms, previous medications, systemic disorders noted.Culture-positive developed 7 eyes (2 men...
To compare 1-year follow-up results of photorefractive keratectomy (PRK) with mitomycin C (MMC) and laser in situ keratomileusis (LASIK) for custom correction myopia.Eighty-eight eyes 44 patients moderate myopia were randomised to PRK 0.002% MMC 1 min one eye LASIK the fellow eye. The was evaluated.There no differences between MMC-PRK preoperatively. Forty-two completed follow-up. achieved better uncorrected visual acuity (p = 0.03) best-spectacle-corrected (p<0.001) year after surgery. SE...
To assess the Acanthamoeba trophozoite viability in vitro and treatment of keratitis a hamster model using ultraviolet light A (UV-A) riboflavin (B2).A sample sp. cultured was transferred to 96-well plate exposed B2 UV-A (365 nm wavelength) at power density 3 mW/cm(2), 8 mm spot diameter, for 30 minutes. The exposure done triplicate. Control groups were prepared triplicate as well: blank control, only, dead control. Cell assessment trypan blue dye exclusion method. induced Chinese hamsters;...
We investigated early mediators of inflammation following excimer laser ablation in a rabbit cornea model. The ability topical anti-inflammatory agents to influence these responses was also examined.Adult New Zealand white rabbits were subjected photorefractive keratectomy with 193-nm argon fluoride laser. Prostaglandin E2 and leukotriene B4 levels measured using an enzyme immunoassay, leukocyte infiltration determined histologically.Prostaglandin production rapid sustained, but we unable...
Aims To determine prevalence of pterygium, its role as main cause unilateral and bilateral visual impairment blindness impact on refractive errors from adults living in a high ultraviolet exposure area the Brazilian Amazon Region. Methods Cluster sampling was used randomly selecting subjects ≥45 years age urban rural areas Parintins city. Eligible were enumerated through door-to-door household survey invited for an eye exam including refraction. Pterygium assessed considering location...
Purpose: To compare photorefractive keratectomy (PRK) with prophylactic use of mitomycin C (MMC) and LASIK in custom surgeries for myopic astigmatism. Methods: Eighty-eight eyes 44 patients a minimum estimated ablation depth 50 µm were randomized to receive PRK MMC 0.002% 1 minute one eye the fellow eye. Uncorrected visual acuity (UCVA), best spectacle-corrected (BSCVA), cycloplegic refraction, slit-lamp microscopy, contrast sensitivity, specular aberrometry, subjective questionnaire...
Purpose To determine the prevalence and causes of visual impairment blindness in adults aged 45 years older from Parintins, Brazilian Amazon Region.Methods A random cluster sampling method was used to identify subjects age urban rural census sectors Parintins city, Amazonas State, March 2014 May 2015. Participants underwent a detailed ocular examination, including presenting (PVA) best corrected acuity (BCVA). The main cause PVA<20/32 per eye determined.Results total 2384 were enumerated...
Purpose: The purpose of this study was to assess blepharospasm patients regarding the effect botulinum toxin in ocular surface parameters. Methods: A prospective performed treated with onabotulinumtoxinA. smartphone (iPhone 6S, Apple) and custom-made software were used record eyelid movements for 3 minutes a standardized manner. Optical coherence tomography tear meniscus area. Tear break-up time Ocular Surface Disease Index questionnaire also evaluated. Patients assessed before 15 days after...
The effects on ocular integrity of three surgical techniques to correct refractive errors were compared. Ten matched pairs eyes (right and left eyes) freshly enucleated from pigs underwent radial keratotomy (RK) (four incisions, 3.50-millimeter clear zone) in one eye photorefractive keratectomy (PRK) with the 193-nanometer excimer laser (10.00- diopter myopic correction, 6.00-millimeter ablation diameter) fellow eye. Another 16 under- went phototherapeutic (PTK) at various depths; another 10...