A5068274448- Facial Rejuvenation and Surgery Techniques
- Dermatologic Treatments and Research
- Botulinum Toxin and Related Neurological Disorders
- Body Contouring and Surgery
- Hair Growth and Disorders
- Facial Nerve Paralysis Treatment and Research
- Body Image and Dysmorphia Studies
- Systemic Lupus Erythematosus Research
- Autoimmune Bullous Skin Diseases
- Surgical Sutures and Adhesives
- Reconstructive Facial Surgery Techniques
- Systemic Sclerosis and Related Diseases
- Ophthalmology and Eye Disorders
- Skin Diseases and Diabetes
- Digital Imaging in Medicine
- Cerebrovascular and Carotid Artery Diseases
- Dupuytren's Contracture and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Autoimmune and Inflammatory Disorders
- Reconstructive Surgery and Microvascular Techniques
- melanin and skin pigmentation
- Skin Protection and Aging
- Tattoo and Body Piercing Complications
- Advancements in Transdermal Drug Delivery
- Gene expression and cancer classification
Erasmus MC
2019-2025
Erasmus University Rotterdam
2018-2024
Rotterdam University of Applied Sciences
2017-2019
Netherlands Pharmacovigilance Centre Lareb
2018
Netherlands Comprehensive Cancer Organisation
2016
Utrecht University
1989-2006
St. Anna Ziekenhuis
2006
University of Amsterdam
1981
Summary Background Hyaluronic acid fillers are known for a reliable safety profile, but complications do occur, even serious vascular adverse events. Objective To improve the of hyaluronic filler treatments. Methods Ultrasound is used to image fillers. Results Before treatment performed with ultrasound, previous treatments can be brought in sight and mapping performed. In case events, surrounding tissues visible. Dislocation, abscesses, events seen. Under ultrasound guidance, hyaluronidase...
Hyaluronic acid fillers are known for a reliable safety profile, but complications do occur, even serious vascular adverse events.To improve the treatment outcome after event with use of hyaluronic filler treatments.Duplex ultrasonography is used to detect causing intra-arterial obstruction.If treated in time, 1 single ultrasonographically guided injections hyaluronidase into deposit will prevent skin necrosis.Because duplex adds extra essential information, its may become an integral part...
For the treatment of vascular adverse events caused by filler injections, duplex ultrasound imaging may be used. The findings examination and clinical features reticulated livedoid skin patterns were compared with hemifaces anatomy.
Vascular adverse events (VAEs) occurring during injections of soft-tissue fillers are still considered a challenging issue for both patients and practitioners. Hyaluronidase can dissolve hyaluronic acid (HA)-based VAE. For VAEs induced by non-HA fillers, the absence an "antidote" is regarded as exceptionally challenging.
This narrative review explores the various injection techniques utilized in facial filler procedures, emphasizing their applications, benefits, and potential complications. The increasing demand for total contouring rejuvenation has led to a rise use of volumizing fillers integration these procedures with other treatments such as toxins, threads, lasers, radiofrequency, ultrasound. Achieving satisfactory results necessitates comprehensive understanding anatomy effects aging on skin tissue....
*Clinic Ebbelaar, Utrecht, The Netherlands †Department of Dermatology, Leiden University Medical Center, Leiden, ‡Division Laboratories, Pharmacy and Biomedical Genetics, Department Pathology, Center §Department Erasmus Rotterdam, authors have indicated no significant interest with commercial supporters.
Nonsurgical rhinoplasty with cross-linked hyaluronic acid (HA) fillers is popular for enhancing nasal esthetics, especially in Asian patients seeking dorsal augmentation. While are expected to last 6 12 months, evidence shows they can persist years, causing delayed complications like broad bridges, termed "Avatar Nose." This case report describes 3 this phenomenon and highlights the role of high-resolution ultrasound diagnosis management. From January November 2024, bridges following HA...
Even though manufacturers claim that the dermal fillers are nontoxic and nonimmunogenic, adverse events may occur. Clinically histologically, most of late onset present as an inflammatory response. To assess whether HLA polymorphisms associated with late-onset related to fillers. A total 211 patients were included, whom 129 experienced different (Inflammation group) 82 who did not (Reference group). Patients completed a standardized questionnaire provided blood sample or oral swap for...
Injecting soft tissue fillers into the deep plane of forehead carries risk injection-related visual compromise due to specific course arterial vasculature.The aim this study was investigate 2- and 3-dimensional location change branch supratrochlear supraorbital artery, respectively.A total 50 patients (11 males 39 females; mean age, 49.76 [13.8] years, body mass index, 22.53 [2.6] kg/m2) were investigated with ultrasound imaging. The thickness distance arteries from skin bone surface...
Abstract Background Adverse vascular event management following hyaluronic acid–based aesthetic injections relies on the administration of hyaluronidase which is capable enzymatically degrading injected product and improving clinical symptoms. Two protocols are currently available to manage such complications: “ultrasound-guided targeted” “flooding”. Objectives The aim this study was compare 2 in terms volume utilized, onset degree improvement. Methods A comparative case series 39 patients...
Facial overfilled syndrome is an adverse event following minimally invasive soft tissue filler injections. It presents in most cases as excess midfacial volume and/or unnatural smile which difficult to detect due the absence of standardized evaluation methods.To showcase how identify, evaluate, and treat facial by utilizing ultrasound simultaneous hyaluronidase injections.Twenty-eight consecutive patients (26 females, 2 males) were enrolled this study was performed evaluate location...
Noninflammatory nodules may be persistent to dissolve. To evaluate the possible reasons, a case series of ultrasound images and medical data patients who were prospectively referred with noninflammatory evaluated.A total 27 but without signs inflammation included. All cases assessed an 18-MHz linear device. Exact location filler material was noted. Relations clinical analyzed using chi-square tests.Early onset complaints (<2 weeks) found in 16 late (>2 11. had multiple nodules. In all cases,...
Interest in Doppler ultrasound (DUS) analysis of the face has grown cosmetic medicine, particular for injectable fillers. When dealing with complications, DUS advantage easily visualizing filler and identifying problem relation to patient's anatomy. working hyaluronic acid filler, ultrasound-guided injections hyaluronidase can precisely target problem. In addition, be used study anatomy a patient, specifically prevent intravascular injections. We predict that few years' time will become...
Recently we have been able to induce pathological skin reactions with UVB, UVA and visible light in patients lupus erythematosus (LE). The had the appearance of spontaneously developed LE lesions. In present study, using polymorphic eruption as controls, subsequently investigated what types immunohistochemical abnormalities were found these It was shown that induced lesions, phenotypically similar inflammatory cells evolved Granular deposits immunoreactants, most occurred 12 out 16 7-10 days...
The tear trough is one of the most challenging facial regions for soft-tissue filler injections. A thorough understanding underlying facial, muscular, and vascular anatomy crucial to perform safe effective injectable treatments.The authors sought evaluate location function angular vein in 3 different expressions: repose, smiling, max. orbicularis oculi contraction.Twenty study participants with a mean age 48.3 years BMI 24.5 kg/m2 were investigated via functional ultrasound imaging. diameter...
Adverse events (AE) after COVID-19 vaccines, particularly, but not solely, with those messenger RNA (mRNA)-based have rarely been reported in patients previously treated dermal fillers (DF).To evaluate the morphology, clinical characteristics, timing of presentation, and outcomes inflammatory AE appeared injected DF, anti-COVID-19 vaccination.Descriptive study a case series 20 consecutive collected occurrence filled areas post vaccination.From January 2021 to July 2021, we analyzed reactions...
The exact etiology of late inflammatory reactions (LIRs) to hyaluronic acid (HA) fillers is currently unknown. Some argue that these result from a hypersensitivity reaction, although evidence support this very scarce. Most reports on such are not substantiated by positive skin tests. purpose our study was determine whether immediate or delayed type reaction follows filler injections.Twelve patients were referred for general allergic screening (patch tests), as well specific intradermal...