Fernando Alfageme

ORCID: 0000-0002-0962-9783
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About
Contact & Profiles
Research Areas
  • Cutaneous Melanoma Detection and Management
  • Hidradenitis Suppurativa and Treatments
  • Cutaneous lymphoproliferative disorders research
  • Colorectal and Anal Carcinomas
  • Autoimmune Bullous Skin Diseases
  • Nail Diseases and Treatments
  • Dermatologic Treatments and Research
  • Tumors and Oncological Cases
  • Vascular Malformations and Hemangiomas
  • Cancer and Skin Lesions
  • Anorectal Disease Treatments and Outcomes
  • Autoimmune and Inflammatory Disorders
  • Nonmelanoma Skin Cancer Studies
  • Genetic and rare skin diseases.
  • Soft tissue tumors and treatment
  • Vascular Tumors and Angiosarcomas
  • Dermatology and Skin Diseases
  • Dermatological and COVID-19 studies
  • Chemotherapy-related skin toxicity
  • Urticaria and Related Conditions
  • Cancer Diagnosis and Treatment
  • Wound Healing and Treatments
  • Dermatological and Skeletal Disorders
  • Polyomavirus and related diseases
  • AI in cancer detection

Hospital Universitario Puerta de Hierro Majadahonda
2016-2025

Clinica Universidad de Navarra
2024

Universidad Autónoma de Madrid
1998-2022

Hospital Universitario Infanta Sofía
2017

Hospital General Universitario Gregorio Marañón
2009-2014

Hospital General de La Rioja
2011-2012

Hospital Universitario del Sureste
2011

Universidad Nacional de Colombia
2002-2011

Centre National de la Recherche Scientifique
2003

To support standardization for performing dermatologic ultrasound examinations.An international working group, called DERMUS (Dermatologic Ultrasound), was formed, composed of physicians who have been on a regular basis and publishing in peer-reviewed articles ultrasound. A questionnaire 5 critical issues about performance the examinations prepared distributed by e-mail. The areas discussion included technical aspects, main application, minimum number per year required assessing competence,...

10.7863/ultra.15.06046 article EN Journal of Ultrasound in Medicine 2016-02-17

Abstract Background It has been reported that clinical evaluation consistently underestimates the severity of hidradenitis suppurativa ( HS ). Objective To determine usefulness ultrasound as a diagnostic tool in compared with examination and to assess subsequent modification disease management. Methods Cross‐sectional multicentre study. Severity classification therapeutic approach according vs. were compared. Results Of 143 patients included. Clinical scored 38, 70 35 Hurley stage I, II III...

10.1111/jdv.15710 article EN Journal of the European Academy of Dermatology and Venereology 2019-05-24

Abstract Dermatologic ultrasound is a recent application of for the evaluation healthy skin and appendages their diseases. Although scientific literature regarding this still not sufficient evidence-based guidelines, general recommendations issued by societies are necessary. The EFSUMB (European Federation Societies Ultrasound in Medicine Biology) steering committee dermatologic has developed series consensus position statements main fields (technical requirement, normal appendages,...

10.1055/a-1161-8872 article EN Ultraschall in der Medizin - European Journal of Ultrasound 2020-05-07

BACKGROUND Staging and monitoring of patients with hidradenitis suppurativa (HS) have been traditionally based on clinical findings. However, the physical examination may show important limitations because its poor sensitivity for differentiating between different lesion subtypes, low to define disease's activity. OBJECTIVE To develop a consensus ultrasound (US) report that could summarize relevant anatomical characteristics staging considering experience radiologists dermatologists working...

10.1097/dss.0000000000001147 article EN Dermatologic Surgery 2017-05-23

<b><i>Background:</i></b> Adalimumab is the only approved compound for treatment of adult patients with moderate-to-severe hidradenitis suppurativa (HS) who did not respond to a systemic classical treatment. Despite its significant short- and long-term efficacy, percentage do sufficiently. Moreover, some primary responders experience response loss time. <b><i>Objective:</i></b> To analyse effectiveness adalimumab dose intensification in HS...

10.1159/000503606 article EN Dermatology 2019-10-18

Hidradenitis suppurativa (HS) is a painful chronic inflammatory skin disease that affects up to 4% of the European adult population. International Suppurativa Severity Score System (IHS4) dynamic scoring tool was developed be incorporated into doctor's daily clinical practice and studies. This helps measure severity guides therapeutic strategy. However, IHS4 assessment time-consuming manual process, with high inter-observer variability dependence on observer's expertise.

10.1111/srt.13357 article EN cc-by-nc-nd Skin Research and Technology 2023-06-01

Abstract Background Tofacitinib, filgotinib, and upadacitinib, are Janus kinase inhibitors (iJAKs) approved for inflammatory bowel disease (IBD) treatment. Although no comparative studies exist, potential differences in efficacy safety attributed to vitro-demonstrated affinity of each molecule different JAK isoforms. JAK1 plays a crucial role modulating cytokine-mediated immune responses, such as IL-6 interferon, which involved inflammation skin homeostasis. Its inhibition can promote...

10.1093/ecco-jcc/jjae190.1079 article EN Journal of Crohn s and Colitis 2025-01-01

Abstract Background So far, the evidence on use of ultrasound (US) in hidradenitis suppurativa (HS) demonstrates utility US diagnosis, scoring and assessment HS; however, to date, there is no international consensus statement HS, several published guidelines do not include this topic. Objectives To create an using HS that can cover validate relevant aspects. Methods A three‐round Delphi study with a panel experts representing four continents working their daily practice. The inclusion...

10.1111/jdv.20600 article EN Journal of the European Academy of Dermatology and Venereology 2025-02-18

The interaction of high-frequency ultrasound waves with the skin provides basis for noninvasive, fast, and accessible diagnostic imaging. This tool is increasingly used in cancer inflammatory conditions as well cosmetic dermatology. article reviews basic principles its applications different areas La ecografía cutánea es una técnica dermatológica de diagnóstico por imagen basada en la interacción los ultrasonidos alta frecuencia con piel. Su carácter no invasivo, rápido y accesible hace que...

10.1016/j.adengl.2014.10.002 article ES cc-by-nc-nd Actas Dermo-Sifiliográficas 2014-11-05

Proposal for an Assessment TrainingProgram in Dermatologic Ultrasound by the DERMUS Group ermatologic ultrasound has been growing rapidly line with development of more potent machines and highfrequency probes.][3][4][5][6] To date, several training programs other areas have reported, such as musculoskeletal, [7][8][9][10][11] emergency, 12-14 cardiology, 15 anesthesiology 16 fields.Nevertheless, dermatologic a new application still lacks international formal or accreditation.Thus, increasing...

10.7863/ultra.15.10068 article EN Journal of Ultrasound in Medicine 2016-09-14

10.1016/j.ad.2014.03.007 article ES cc-by-nc-nd Actas Dermo-Sifiliográficas 2014-07-02

Ciudad, Cristina MD*; Avilés, Jose Antonio MD, PHD*; Alfageme, Fernando Lecona, Manuel MD†; Suárez, Ricardo Lázaro, Pablo PHD* Author Information

10.1111/j.1524-4725.2010.01531.x article IT Dermatologic Surgery 2010-04-02

We retrospectively collected cases of surgically proven extradigital glomus tumor (EDGT) and reviewed their demographic, clinical, sonography features. A total 18 single, subcutaneous EDGTs were gathered. All but one located in the extremities. typically appear as a small, hypoechoic, homogeneous, or slightly inhomogeneous, well-delimited nodule, disposed horizontally painful under probe pressure. Intranodular vascularization is always present. Feeding artery efferent vein are typical...

10.7863/ultra.16.03023 article EN Journal of Ultrasound in Medicine 2016-12-03

Background: Primary cutaneous lymphoma is a rare extranodal non-Hodgkin’s confined to the skin. The data on imaging findings of primary lymphomas are largely lacking and current diagnosis based clinical histopathological examination. With advances in dermatological ultrasound molecular imaging, newer perspectives evaluation available. Objective: To review describe patient’s with lymphoma. Methods: A multicentric, retrospective observational study was undertaken four countries high resolution...

10.1259/bjr.20180904 article EN British Journal of Radiology 2019-01-04

Hidradenitis suppurativa (HS) is a chronic inflammatory disease of the follicular unit characterized by recurrent, painful, skin lesions including nodules, abscesses, tunnels, and mutilating scarring. Intralesional corticosteroids injection (ICI) for HS has received little attention in scientific literature. We evaluate clinical response ICI acute aim to identify new applications ultrasound-assisted procedures management.An observational, retrospective, multicenter study patients treated...

10.1080/09546634.2019.1655524 article EN Journal of Dermatological Treatment 2019-08-12

In this original research, we present the results in terms of effectiveness and safety bimekizumab for hidradenitis suppurativa real clinical practice. Results indicated significant improvement all activity scores patient-reported outcomes at week 16, including a notable decrease mean IHS4 from 27.1 to 15.6 (p < 0.001), HS-PGA 5.1 3.2 VAS pain 8.3 4.7 0.001) DLQI 21.6 12.6 0.001). Bimekizumab, administered every 2 or 4 weeks, was well-tolerated with no discontinuations new concerns...

10.1111/ajd.14339 article EN Australasian Journal of Dermatology 2024-06-19
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