Gianluca Nazzaro

ORCID: 0000-0001-8534-6497
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About
Contact & Profiles
Research Areas
  • Dermatological diseases and infestations
  • Cancer and Skin Lesions
  • Nail Diseases and Treatments
  • Autoimmune and Inflammatory Disorders
  • Cutaneous lymphoproliferative disorders research
  • Nonmelanoma Skin Cancer Studies
  • Hidradenitis Suppurativa and Treatments
  • Cutaneous Melanoma Detection and Management
  • Colorectal and Anal Carcinomas
  • Genetic and rare skin diseases.
  • Infectious Diseases and Mycology
  • Chemotherapy-related skin toxicity
  • Autoimmune Bullous Skin Diseases
  • Dermatological and COVID-19 studies
  • Fungal Infections and Studies
  • Dermatology and Skin Diseases
  • Dermatologic Treatments and Research
  • Eosinophilic Disorders and Syndromes
  • Hedgehog Signaling Pathway Studies
  • Acne and Rosacea Treatments and Effects
  • Mycobacterium research and diagnosis
  • Vascular Tumors and Angiosarcomas
  • Medicine and Dermatology Studies History
  • Herpesvirus Infections and Treatments
  • Beetle Biology and Toxicology Studies

Ospedale Maggiore
2016-2025

Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2016-2025

University of Milan
2016-2025

National Student Clearinghouse Research Center
2024

Creative Commons
2022

Group Image (Poland)
2022

Weatherford College
2022

Collegio Carlo Alberto
2021

Centro de Investigación en Salud Dr. Hugo Mendoza
2019

PresentationA 33-year-old male, recently returned from a trip to Argentina, was admitted with an ulcer on the left temple, erythematous oedema of eyelid, cheek (Figure 1 A,B), and preauricular laterocer-

10.5826/dpc.1402a81 article EN cc-by-nc Dermatology Practical & Conceptual 2024-04-30

Abstract Background Tirbanibulin 1% ointment is approved for the field treatment of Olsen grade I actinic keratoses (AKs) face and scalp. Methods We performed a multicenter retrospective study involving 15 dermatologic units in Italy to investigate efficacy tolerability tirbanibulin real‐life setting. 250 patients were enrolled. Tirbanibulin, ointment, was applied daily five consecutive days. The measured with modifications Actinic Keratosis Area Severity Index (AKASI). A satisfactory...

10.1111/ijd.17168 article EN cc-by-nc International Journal of Dermatology 2024-04-11

Vismodegib and sonidegib are smoothened (SMO) inhibitors approved for the treatment of advanced basal cell carcinoma (aBCC). This study investigates real-world experiences outcomes associated with these therapies across multiple Italian centers. A retrospective, observational, multicenter was conducted. Medical records patients local (laBCC) treated SMO outside clinical trials from July 2019 to April 2024 were analyzed. total 57 included in study, 19 (33.3%) receiving vismodegib 38 (66.7%)...

10.4081/dr.2025.10196 article EN cc-by-nc Dermatology Reports 2025-02-18

Abstract Background The detection of cutaneous metastases (CMs) from various primary tumours represents a diagnostic challenge. Objectives Our aim was to evaluate the general characteristics and dermatoscopic features CMs different tumours. Methods Retrospective, multicentre, descriptive, cross‐sectional study biopsy‐proven CMs. Results We included 583 patients (247 females, median age: 64 years, 25%–75% percentiles: 54–74 years) with 632 CMs, which 52.2% ( n = 330) were local, 26.7% 169)...

10.1111/jdv.19962 article EN Journal of the European Academy of Dermatology and Venereology 2024-03-14

Nevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin (GS), is a genetic disorder characterized by the development of multiple cutaneous BCCs due to mutations in hedgehog signaling pathway. The use pathway inhibitors—vismodegib and sonidegib—has emerged promising therapeutic strategy for managing individuals with GS. In retrospective study conducted between March 2012 January 2024, cohort 16 patients who received treatment either sonidegib or vismodegib were analyzed. primary...

10.3390/cancers16122166 article EN Cancers 2024-06-07

Poromas are benign cutaneous sweat gland tumours that challenging to identify. The dermoscopic features of poromas not well characterized.To determine the clinical-dermoscopic poromas.Cross-sectional, observational study 113 and 106 matched control lesions from 16 contributors eight countries. Blinded reviewers evaluated clinical present in each image.Poromas were most commonly non-pigmented (85.8%), papules (35.4%) located on non-acral sites (65.5%). In multivariate analysis, associated...

10.1111/jdv.14729 article EN Journal of the European Academy of Dermatology and Venereology 2017-12-01

10.2340/actadv.v105.42571 article EN cc-by-nc Acta Dermato Venereologica 2025-01-24

Background/ Objectives: Melanoma is the most severe form of skin cancer, with incidence increasing worldwide. However, there still a lack strong evidence to support melanoma screening, and screening strategies vary among healthcare systems. This study aims compare effectiveness two strategies, total-body (TBS) examination lesion-directed (LDE) suspicious lesion, in detecting at earlier stages (thickness<0.8mm). Methods: Data was collected from all patients who came for dermatology...

10.20944/preprints202502.0200.v1 preprint EN 2025-02-04

Abstract Background So far, the evidence on use of ultrasound (US) in hidradenitis suppurativa (HS) demonstrates utility US diagnosis, scoring and assessment HS; however, to date, there is no international consensus statement HS, several published guidelines do not include this topic. Objectives To create an using HS that can cover validate relevant aspects. Methods A three‐round Delphi study with a panel experts representing four continents working their daily practice. The inclusion...

10.1111/jdv.20600 article EN Journal of the European Academy of Dermatology and Venereology 2025-02-18

Introduction: Nail involvement in patients with crusted scabies is well known. It characterized clinically by subungual hyperkeratosis and onycholysis. “Classical” involving the nails was rarely reported. Case Presentations: We describe two classical located exclusively on a toenail. In first patient, complete disappearance of nail plate observed. second thick, greysh-brown, plate, surrounded scales, Both were successfully treated permethrin ivermectin. Discussion: A possible explanation...

10.1159/000545326 article EN Skin Appendage Disorders 2025-03-24

Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Dermatology HomeNew OnlineCurrent IssueFor Authors Podcast Publications Network Open Cardiology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Surgery Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy...

10.1001/jamadermatol.2013.8860 article EN JAMA Dermatology 2014-02-01

Hidradenitis suppurativa (HS) is a debilitating, chronic-relapsing, inflammatory skin disease of apocrine gland-bearing skin, presenting with nodules, abscesses, and fistulae. Ultrasound used to classify HS lesions but evaluation vascularization, related tissue inflammation, needs Color Doppler. The aim was correlate vascularization patients' reported pain.Vascularization assessed Hitachi Arietta V-70 sonographer according four-category system ranging from absent (0), minimal (1), moderate...

10.1111/srt.12729 article EN Skin Research and Technology 2019-05-29

Incidence of cutaneous melanoma is steadily growing, and its early recognition paramount importance. Small, pigmented lesions often represent a challenge for the clinician, as predictors have not yet been uniquely identified in this setting.To identify dermoscopic features that aid distinguishing small diameter melanomas (≤5 mm) from equivocal melanocytic nevi measuring ≤5 mm.A retrospective multicenter study was conducted to collect demographics, clinical pictures (i) histology-proven flat...

10.1111/ijd.16710 article EN cc-by-nc-nd International Journal of Dermatology 2023-05-20

The effects of UV radiation on the skin and its damage mechanisms are well known. New modalities exogenous photoprotection have been studied. It was demonstrated that Polypodium leucotomos extract acts as an antioxidant, photoprotectant, antimutagenic, anti-inflammatory, immunoregulator. is effective when taken orally and/or applied topically to support prevention cancers. also has important role in preventing photoaging. This review aims report through which analyze uses oncodermatology...

10.3390/jcm12020673 article EN Journal of Clinical Medicine 2023-01-14
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