A5027502083- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Autoimmune Neurological Disorders and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Autophagy in Disease and Therapy
- Pulmonary Hypertension Research and Treatments
- Synthesis of heterocyclic compounds
- Cardiac Valve Diseases and Treatments
- Mesenchymal stem cell research
- Ferroptosis and cancer prognosis
- RNA Research and Splicing
- Cardiovascular Issues in Pregnancy
- Sulfur-Based Synthesis Techniques
- Pediatric health and respiratory diseases
- Neuroscience and Neural Engineering
- Myasthenia Gravis and Thymoma
- Lung Cancer Treatments and Mutations
- Carbon Nanotubes in Composites
- Dysphagia Assessment and Management
- Epigenetics and DNA Methylation
- Advanced Memory and Neural Computing
- Voice and Speech Disorders
- Immune cells in cancer
- Protein Degradation and Inhibitors
Shanghai Changzheng Hospital
2019-2024
Second Military Medical University
2016-2024
People's Liberation Army 411 Hospital
2024
Ruijin Hospital
2024
Shanghai Jiao Tong University
2024
Changhai Hospital
2016
Abstract Purpose The long non-coding RNA MALAT1 is a predictive marker in several solid tumors with highly conserved sequences. However, the role of development laryngeal or hypopharyngeal cancer remains unclear. Methods Tumor tissues and adjacent non-cancer 24 patients were collected. We detected expression tissues. Moreover, we developed silencing model human tumor cells by transfecting small interfering into carcinoma cell line Hep-2 pharyngeal FaDu Lipofectamine 2000 system. Cell cycle...
Background: To promote carcinogenesis through diverse molecular pathways involving dysregulation of gene expression and abnormalities.
Small-cell lung cancer (SCLC) presenting with syncope as the initial symptom is rare in adults. This onset of tumour-induced cannot be screened or differentiated by coronary angiography, magnetic resonance angiography neck 24-hour dynamic electrocardiogram. We herein describe case a 61-year-old man who presented recurrent that resolved after first course chemotherapy (carboplatin plus etoposide) for SCLC. A mass measuring 57×53 mm was identified left hilum, and diagnosis limited-disease SCLC...
This study aims to investigate the role of Sirt5 in regulating eosinophil maturation and activation, specifically focusing on primary eosinophils mice at genetic level. Additionally, elucidate underlying mechanism eosinophilic inflammation metabolism identify potential drug targets for treatment chronic sinusitis. The findings this will provide new insights a solid theoretical basis development novel therapeutic strategies rhinosinusitis (eCRS). Our investigated gene expression both non-eCRS...
The AlkB homolog 7 (ALKBH7) is a nonheme iron (II) α-ketoglutarate-dependent dioxygenase superfamily member, which may affect the progression of several types human cancer. However, biological effect, especially immune-related ALKBH7 in HNSC remains unclear. Herein, databases were employed at first to assess different expression as well their relationship prognosis, RNA modification, DNA methylation modulation, immune microenvironment and chemotherapeutic responses various cancers. We found...
NUT癌是以染色体15q14上睾丸基因核蛋白（NUTM1）重排为特征的一种罕见的恶性肿瘤，其发病机制及治疗方法目前尚不明确。上海长征医院医院耳鼻咽喉头颈外科收治了1例发生于鼻腔的NUT癌患者，为28岁男性，其鼻腔肿瘤发展迅速，并有上颌窦骨质破坏。初次活检病理诊断为非角化未分化癌，进一步手术治疗后，经荧光标记的原位杂交技术证实为NUT癌。本文结合文献回顾报告了鼻腔NUT癌这一少见实体瘤的临床、病理特征及治疗策略。.