Uroghupatei P. Iyegha

ORCID: 0000-0002-9481-3728
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About
Contact & Profiles
Research Areas
  • Emergency and Acute Care Studies
  • Trauma and Emergency Care Studies
  • Sepsis Diagnosis and Treatment
  • Cardiac Arrest and Resuscitation
  • Cardiac, Anesthesia and Surgical Outcomes
  • Abdominal Trauma and Injuries
  • Palliative Care and End-of-Life Issues
  • Disaster Response and Management
  • Pancreatitis Pathology and Treatment
  • Healthcare cost, quality, practices
  • Electroconvulsive Therapy Studies
  • High Altitude and Hypoxia
  • Gastroesophageal reflux and treatments
  • Appendicitis Diagnosis and Management
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Electrolyte and hormonal disorders
  • Patient Safety and Medication Errors
  • Pancreatic and Hepatic Oncology Research
  • Biomedical and Chemical Research
  • Intestinal and Peritoneal Adhesions
  • Thermal Regulation in Medicine
  • Neuroscience of respiration and sleep
  • Hemodynamic Monitoring and Therapy
  • Pancreatic function and diabetes
  • Diet and metabolism studies

Regions Hospital
2019-2023

American Association for the Surgery of Trauma
2019

University of Michigan
2019

Indiana University – Purdue University Indianapolis
2019

North Memorial Health Care
2019

University of Minnesota
2011-2019

Office of Naval Research
2015

American College of Surgeons
2015

Minneapolis Institute of Arts
2014

Interfacility transfer of patients from Level III/IV to I/II (tertiary) trauma centers has been associated with improved outcomes. However, little data are available classifying the specific subsets that derive maximal benefit a tertiary center. Drawbacks include increased secondary overtriage. Here, we ask which injury patterns survival following interfacility transfer.

10.1097/ta.0000000000002248 article EN Journal of Trauma and Acute Care Surgery 2019-03-07

Near-infrared spectroscopy-derived tissue hemoglobin saturation (StO2) is a noninvasive measurement that reflects changes in microcirculatory perfusion. Previous studies trauma patients have shown correlation between low StO2 levels and mortality, organ failure, severity of injury. The goals this study were to identify the incidence critically ill patient population surgical intensive care unit (SICU) evaluate relationship clinical outcomes.We conducted prospective cohort at University...

10.1097/ta.0b013e3182ab07a4 article EN Journal of Trauma and Acute Care Surgery 2014-02-19

We have previously demonstrated survival benefit to induced hypothermia in a porcine model of controlled hemorrhagic shock simulating an associated delay definitive care. In the current study, we wished evaluate effects environmental with addition polytrauma. Sixteen pigs were randomized normothermic (39°C, n = 7) or hypothermic (34°C, 9) groups. The included instrumentation, chest injury (captive bolt device), hemorrhage systolic blood pressure (SBP) ∼50 mmHg, and crush liver injury....

10.1097/shk.0b013e3182657a21 article EN Shock 2012-07-07

D-ß-hydroxybutyrate (BHB) and melatonin (M) treatment improves survival in animal models of hemorrhagic shock. Here, we evaluated the safety BHB/M via 2 routes administration a porcine shock/polytrauma model. Furthermore, assessed serum concentrations after intravenous intraosseous infusion different doses healthy pigs. Pigs underwent pulmonary contusion, liver injury, hemorrhage. Injured animals were treated with an or bolus lactated Ringer’s solution (LR), followed by 4 h continuous...

10.1097/shk.0000000000000315 article EN Shock 2015-02-18

Psychogenic polydipsia is prevalent amongst psychiatric patients, but less common in the general population. Generally, hyponatremia ensues with complications of cerebral edema resulting confusion, seizures, coma, and death. Rapid correction serum sodium levels can lead to further osmotic demyelination neurons, e.g. central pontine myelinolysis.We present a case 32-year-old male who presented seizures while being treated at drug rehabilitation facility. He was discovered be hyponatremic...

10.12659/ajcr.882772 article EN American Journal of Case Reports 2012-01-01

Hemorrhagic shock and injury lead to dramatic changes in metabolic demands continue be a leading cause of death. We hypothesized that altering the preinjury state with carbohydrate load prior would affect subsequent responses improved survival.Sixty-four pigs were randomized fasted (F) or prefeeding (CPF) groups 12 h experiment. The CPF received an oral 1 anesthesia. All underwent standardized injury/hemorrhagic protocol. Physiologic parameters laboratory values obtained at set time...

10.1097/shk.0000000000000324 article EN Shock 2015-01-07
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