A5023171900- Cardiac, Anesthesia and Surgical Outcomes
- Trauma and Emergency Care Studies
- Cardiac Arrest and Resuscitation
- Pancreatitis Pathology and Treatment
- Surgical site infection prevention
- COVID-19 and healthcare impacts
- Pancreatic and Hepatic Oncology Research
- Hip and Femur Fractures
- Pancreatic function and diabetes
- Appendicitis Diagnosis and Management
- Frailty in Older Adults
- Emergency and Acute Care Studies
- Intensive Care Unit Cognitive Disorders
- Pelvic and Acetabular Injuries
- Abdominal Trauma and Injuries
- Enhanced Recovery After Surgery
- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma Management and Diagnosis
- Respiratory Support and Mechanisms
- Radiation Dose and Imaging
- Alcoholism and Thiamine Deficiency
- Hemodynamic Monitoring and Therapy
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Gallbladder and Bile Duct Disorders
- Automotive and Human Injury Biomechanics
Essentia Health
2020-2025
St. Mary's Medical Center
2019-2024
University of Minnesota, Duluth
2021-2024
Hôpital Cochin
2024
Assistance Publique – Hôpitaux de Paris
2024
Sorbonne Paris Cité
2024
Université Paris Cité
2024
Institut national de recherche en informatique et en automatique
2024
All India Institute of Medical Sciences Rishikesh
2022
University of Minnesota Medical Center
2020-2022
Aortic occlusion (AO) is a lifesaving therapy for the treatment of severe traumatic hemorrhagic shock; however, there remains controversy whether AO should be accomplished via resuscitative thoracotomy (RT) or endovascular balloon aorta (REBOA) in zone 1.To compare outcomes RT vs REBOA 1.This was comparative effectiveness research study using multicenter registry postinjury from October 2013 to September 2021. 1 (above celiac artery) compared with performed emergency department facilities...
This study assessed the feasibility of a preoperative high-intensity interval training (HIT) programme in patients awaiting elective abdominal aortic aneurysm repair.In this trial, participants were allocated by minimization to HIT or usual care. Patients group offered three exercise sessions per week for 4 weeks, and weekly maintenance if surgery was delayed. Feasibility acceptability outcomes were: rates screening, eligibility, recruitment, retention, outcome completion, adverse events...
Pre-operative intervention to improve general health and readiness for surgery is known as prehabilitation. Modification of risk factors such physical inactivity, smoking, hazardous alcohol consumption an unhealthy weight can reduce the peri-operative morbidity patient outcomes. Interventions may need target multiple behaviours. The acceptability patients unclear. We explored motivation, confidence priority changing behaviours before short-term benefits in comparison with long-term benefits....
BACKGROUND The frailty index is a known predictor of adverse outcomes in geriatric patients. Trauma-Specific Frailty Index (TSFI) was created and validated at single center to accurately identify reliably predict worse among trauma This study aims prospectively validate the TSFI multi-institutional cohort METHODS prospective, observational, trial across 17 American College Surgeons Levels I, II, III centers. All patients (65 years older) presenting during 3-year period were included. status...
Introduction: Alcohol is the most frequently abused drug in United States, and alcohol use disorder (AUD) a common comorbidity intensive care units (ICUs). Patients Methods: We performed retrospective chart review of patients admitted to an ICU between January 2017 March 2019 at tertiary hospital serving large rural population. with diagnoses AUDs were included. excluded if they did not require care. Patient demographics, course, infection type, culture results, mortality evaluated. compared...
Background: Facial fractures are common in traumatic injury. Antibiotic administration practices for facial differ widely. Methods: The Surgical Infection Society's (SIS's) Therapeutics and Guidelines Committee convened to develop guidelines antibiotic the management of fractures. PubMed, Embase, Cochrane database were searched pertinent studies. Pre-operative antibiotics defined as those administered more than 1 hour before surgery. Peri-operative within start surgery depending on type late...
Hysterectomy is one of the most common procedures performed in United States. New techniques utilizing laparoscopic and robotic technology are becoming increasingly common. It unknown if these minimally invasive surgical alter risk site infections (SSI).We a retrospective review all patients undergoing abdominal hysterectomy at our institution between January 2011 June 2013. International Classification Diseases, Ninth edition (ICD-9) codes chart were used to identify by open, laparoscopic,...
Computed tomography (CT) with intravenous (IV) contrast is an important step in the evaluation of blunt trauma patient; however, risk for contrast-induced nephropathy (CIN) these patients still remains unclear. The goal this study was to describe rate CIN at a Level 1 center and identify factors developing CIN.After internal review board approval, we reviewed our registry admitted during 1-year period. Chart used patient demographics, creatinine levels, vital signs. defined as increase by...
BackgroundThe perioperative management of antiplatelet therapy in noncardiac surgery patients who have undergone previous percutaneous coronary intervention (PCI) remains a dilemma. Continuing dual (DAPT) may carry risk bleeding, while stopping increase the major adverse cardiovascular events (MACE).MethodsOccurrence Bleeding and Thrombosis during Antiplatelet Therapy In Non-Cardiac Surgery (OBTAIN) was an international prospective multicentre cohort study treatment, MACE, serious bleeding...
Chronic pancreatitis is a painful and often debilitating disease. Total pancreatectomy with intra-portal islet autotransplantation (TP-IAT) treatment option that allows for pain relief preservation of beta-cell mass, thereby minimizing the complication diabetes mellitus. Cultures harvested islets are positive bacteria, possibly due to frequent procedures prior TP-IAT, such as endoscopic retrograde cholangiopancreatography (ERCP), stenting, or other operative drainage procedures. It unclear...
ABSTRACT BACKGROUND Despite the high incidence of blunt trauma in older adults, there is a lack evidence-based guidance for computed tomography (CT) imaging this population. We aimed to identify an algorithm guide use Pan-Scan (Head/C-spine/Torso) or Selective Scan (Head/C-spine ± Torso). hypothesized that patient’s initial history and exam could be used imaging. METHODS prospectively studied patients aged 65+ at 18 Level I/II centers. Patients presenting >24 h after injury who died upon...
Surgical site infection (SSI) following joint arthroplasty increases length of stay, hospital cost, and leads to patient healthcare provider dissatisfaction. Due the presence non-biologic implants (the prosthetic joint) in these procedures, is often devastating treatment more difficult. For this reason, prevention SSI crucial importance population. Staphylococcus aureus colonizes nares approximately 30-40% population, most common pathogen causing SSI, associated with high morbidity mortality...
Background: Alcohol use disorders (AUD) are common in patients admitted to intensive care units (ICU) and increase the risk for worse outcomes. In this study, we describe factors associated with patient mortality after ICU admission effect of chemical dependency (CD) counseling on outcomes year following admission. Methods: We retrospectively reviewed demographics, hospital data, documentation CD by medical providers all AUD our institution between January 2017 March 2019. Primary were...
Abstract Background Frailty refers to the reduction in homeostatic reserve resulting from an accumulation of physiological deficits over a lifetime. is common older patients undergoing surgery and independent risk factor for post-operative mortality, morbidity increased length hospital stay. In frail individuals, stressors, such as surgery, can precipitate acute deterioration health, manifesting delirium, falls, mobility or continence, rendering these individuals at adverse perioperative...
Obstructive sleep apnea (OSA) is associated with increased systemic oxidative stress, endothelial dysfunction, and activation of pro-inflammatory cascades, which increase host susceptibility to infection. OSA has not been evaluated as a risk factor for surgical site infection (SSI) following colectomy. We hypothesized that increases the SSI after colectomy.We performed retrospective review 507 colectomies took place between August 2011 September 2013. Forty-two patients carried diagnosis...
Objectives Chronic pancreatitis (CP) is an infrequent but debilitating complication associated with CFTR mutations. Total pancreatectomy islet autotransplantation (TPIAT) a treatment option for CP that provides pain relief and preserves β-cell mass, thereby minimizing the of diabetes mellitus. We compared outcomes after TPIAT mutations to without CTFR Methods All TPIATs performed between 2002 2014 were retrospectively reviewed: identifying 20 homozygotes (cystic fibrosis [CF] patients), 19...
Metabolomics-based diagnosis or prediction of risk may improve patient outcomes and understanding the pathogenesis acute pancreatitis (AP). Endoscopic retrograde cholangiopancreatography (ERCP) is a factor for developing AP. This pilot study examined metabolomes patients before after ERCP, hypothesizing that metabolomics could differentiate between who did not develop post-ERCP pancreatitis, biomarkers associated with development AP be identified.Patients at high were prospectively enrolled...
Hemorrhagic shock and injury lead to dramatic changes in metabolic demands continue be a leading cause of death. We hypothesized that altering the preinjury state with carbohydrate load prior would affect subsequent responses improved survival.Sixty-four pigs were randomized fasted (F) or prefeeding (CPF) groups 12 h experiment. The CPF received an oral 1 anesthesia. All underwent standardized injury/hemorrhagic protocol. Physiologic parameters laboratory values obtained at set time...
Objective: To determine the proportion and characteristics of injured rural residents treated at urban trauma centers (TCs), non-trauma (NTCs), TCs, NTCs. Summary Background Data: Timely treatment a designated center improves outcomes for patients with serious injuries, but have limited access to centers. Rural may constitute an underrecognized source care. Methods: We used National Emergency Department Sample conduct retrospective, pooled cross-sectional study ED visits among injury...
Background:Clostridioides difficile infection (CDI) can result in life-threatening illness requiring surgery. Surgical options for managing severe or fulminant, non-perforated C. colitis include total abdominal colectomy with end ileostomy creation of a diverting loop antegrade vancomycin lavage. Methods: The Infection Society's Therapeutics and Guidelines Committee convened to develop guidelines summarizing the current SIS recommendations versus lavage colitis. PubMed, Embase, Cochrane...
Gallbladder disease, one of the most common diseases in United States, ranges from symptomatic gallstones to severe systemic infections cholangitis. Little research is available on how often patients undergoing emergent cholecystectomy also have bacteremia. We hypothesized that blood cultures would be performed rarely cholecystectomy, and positive associated with worse outcomes.