A5100441258- Catalysis for Biomass Conversion
- Bone Tissue Engineering Materials
- Mesoporous Materials and Catalysis
- Land Rights and Reforms
- Graphene and Nanomaterials Applications
- Land Use and Ecosystem Services
- Catalytic Processes in Materials Science
- Catalysts for Methane Reforming
- Catalysis and Hydrodesulfurization Studies
- Urban Planning and Valuation
- Periodontal Regeneration and Treatments
- Metal-Organic Frameworks: Synthesis and Applications
- Epigenetics and DNA Methylation
- Chemical Synthesis and Analysis
- Electrospun Nanofibers in Biomedical Applications
- Electrocatalysts for Energy Conversion
- Zeolite Catalysis and Synthesis
- Traditional Chinese Medicine Analysis
- Cancer-related gene regulation
- Extracellular vesicles in disease
- Digestive system and related health
- Advanced oxidation water treatment
- Advanced Drug Delivery Systems
- Graphene research and applications
- Radical Photochemical Reactions
Fudan University
2025
First Affiliated Hospital of Nanchang University
2025
Nanchang University
2022-2025
National Institute of Biological Sciences, Beijing
2025
Ningbo University of Technology
2025
Tianjin Medical University
2021-2024
Shaoxing University
2022
Chinese People's Armed Police Force
2021
Chinese People's Armed Police General Hospital
2021
Zhejiang University
2014-2020
The challenges in the treatment of extensive bone defects are infection control and regeneration. Bone tissue engineering is currently one most promising strategies. In this study, a short biopeptide with specific osteogenic ability designed by fusion peptide technology encapsulated chitosan-modified poly(lactic acid–glycolic acid) (PLGA) microspheres. (FP) mainly consists an functional sequence (P-15) bone-specific binding (Asp-6), which can regulate formation accurately efficiently....
Biocompatible scaffolding materials play an important role in bone tissue engineering. This study sought to develop and characterize a nano-hydroxyapatite (nHA)/collagen I (ColI)/multi-walled carbon nanotube (MWCNT) composite scaffold loaded with recombinant morphogenetic protein-9 (BMP-9) for engineering by vitro vivo experiments. The nHA/ColI/MWCNT scaffolds were fabricated at various concentrations of MWCNTs (0.5, 1, 1.5% wt) blending freeze drying. porosity, swelling rate, water...
Abstract Intestinal homeostasis relies on the continuous renewal of intestinal stem cells (ISCs), which could be epigenetically regulated. While protein arginine methyltransferase 5 (Prmt5) is known to play a key role in multiple organs as an epigenetic modifier, its specific function maintaining remains elucidated. Here, we show that Prmt5 highly expressed mouse crypts. The deletion results ISCs deficiency, ectopic localization Paneth cells, and spontaneous colitis. Mechanistically,...
Cell-to-cell communication via Delta-Notch signaling is widely used in various tissues and organs to regulate development patterning; however, the mechanisms regulating Notch for precise cell fate decisions remain poorly understood. Similar mammals, intestinal stem cells (ISCs) adult Drosophila midgut generate both absorptive secretory progeny, guided by differential levels of activation. Here we performed a forward genetic screen identified glucosylceramide synthase (GlcT), rate-limiting...
Cell-to-cell communication via Delta-Notch signaling is widely used in various tissues and organs to regulate development patterning; however, the mechanisms regulating Notch for precise cell fate decisions remain poorly understood. Similar mammals, intestinal stem cells (ISCs) adult Drosophila midgut generate both absorptive secretory progeny, guided by differential levels of activation. Here we performed a forward genetic screen identified glucosylceramide synthase (GlcT), rate-limiting...
Cell-to-cell communication via Delta-Notch signaling is widely used in various tissues and organs to regulate development patterning; however, the mechanisms regulating Notch for precise cell fate decisions remain poorly understood. Similar mammals, intestinal stem cells (ISCs) adult Drosophila midgut generate both absorptive secretory progeny, guided by differential levels of activation. Here we performed a forward genetic screen identified glucosylceramide synthase (GlcT), rate-limiting...
Titanium (Ti) and its alloys have been universally used as surgical implants, the clinical need for modifying titanium surfaces to accelerate early stage osseointegration prevent implant loosening is in huge demand. 3D printing technology an accurate controllable method create implants with complex nanostructures, which provide enough space react fit microenvironment of cells. Recently, extracellular vesicles (EVs) attracted attention promoting osteogenesis. The derived from bone marrow...
Bioactive scaffolding materials and efficient osteoinductive factors are key for bone tissue engineering. The present study aimed to mimic the natural repair process using an morphogenetic protein (BMP)-6-loaded nano-hydroxyapatite (nHA)/gelatin (Gel)/gelatin microsphere (GMS) scaffold pre-seeded with marrow mesenchymal stem cells (BMMSCs). BMP-6-loaded GMSs were prepared by cross-linking BMP-6/nHAG/GMS scaffolds fabricated a combination of blending freeze-drying techniques. Scanning...
Titanium (Ti) and titanium alloys have been widely used in the field of biomedicine. However, unmatched biomechanics poor bioactivities conventional Ti implants usually lead to insufficient osseointegration. To tackle these challenges, it is critical develop a novel implant that meets bioadaptive requirements for load-bearing bone defects. Notably, three-dimensional (3D)-printed mimic microstructure mechanical properties natural bones. Additionally, eco-friendly techniques based on...
A Ni@N-CNTs-GS catalyst prepared <italic>via</italic> pyrolysis is shown to be active and stable for the hydrogenation of nitroarenes anilines a direct route.