Louise Owen

ORCID: 0000-0002-9490-6377
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About
Contact & Profiles
Research Areas
  • Neonatal Respiratory Health Research
  • Respiratory Support and Mechanisms
  • Neuroscience of respiration and sleep
  • Congenital Diaphragmatic Hernia Studies
  • Airway Management and Intubation Techniques
  • Infant Development and Preterm Care
  • HIV/AIDS Research and Interventions
  • Theatre and Performance Studies
  • Cardiac Arrest and Resuscitation
  • Adolescent Sexual and Reproductive Health
  • HIV, Drug Use, Sexual Risk
  • Ethics and Legal Issues in Pediatric Healthcare
  • Hepatitis C virus research
  • Irish and British Studies
  • Syphilis Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • Sex work and related issues
  • LGBTQ Health, Identity, and Policy
  • Ethics in Clinical Research
  • Reproductive tract infections research
  • Emergency and Acute Care Studies
  • Non-Invasive Vital Sign Monitoring
  • Tracheal and airway disorders
  • Liver Disease Diagnosis and Treatment
  • Cultural Industries and Urban Development

Murdoch Children's Research Institute
2016-2025

The University of Melbourne
2016-2025

Royal Women's Hospital
2016-2025

Johns Hopkins Medicine
2025

Johns Hopkins Children's Center
2025

Johns Hopkins University
2024-2025

Inland Fisheries Service
2017-2024

University of Tasmania
2019-2024

Royal Central School of Speech and Drama
2024

Bradford Royal Infirmary
2024

Objectives To determine whether the introduction of Obstetrics Emergency Training in line with recommendations Clinical Negligence Scheme for Trusts (CNST) was associated a reduction perinatal asphyxia and neonatal hypoxic–ischaemic encephalopathy (HIE). Design A retrospective cohort observational study. Setting tertiary referral maternity unit teaching hospital. Population Term, cephalic presenting, singleton infants born at Southmead Hospital between 1998 2003 were identified; those by...

10.1111/j.1471-0528.2006.00800.x article EN BJOG An International Journal of Obstetrics & Gynaecology 2006-01-13

The use of high-flow nasal cannulae is an increasingly popular alternative to continuous positive airway pressure (CPAP) for noninvasive respiratory support very preterm infants (gestational age, <32 weeks) after extubation. However, data on the efficacy or safety such in this population are lacking.In multicenter, randomized, noninferiority trial, we assigned 303 receive treatment with either (5 6 liters per minute) CPAP (7 cm water) primary outcome was failure within 7 days. Noninferiority...

10.1056/nejmoa1300071 article EN New England Journal of Medicine 2013-10-10

Treatment with nasal high-flow therapy has efficacy similar to that of continuous positive airway pressure (CPAP) when used as postextubation support in neonates. The the primary means respiratory for preterm infants distress not been proved.

10.1056/nejmoa1603694 article EN New England Journal of Medicine 2016-09-21

<h3>Importance</h3> Preterm infants must establish regular respirations at delivery. Sustained inflations may lung volume faster than short inflations. <h3>Objective</h3> To determine whether a ventilation strategy including sustained inflations, compared with standard intermittent positive pressure ventilation, reduces bronchopulmonary dysplasia (BPD) or death 36 weeks' postmenstrual age without harm in extremely preterm infants. <h3>Design, Setting, and Participants</h3> Unmasked,...

10.1001/jama.2019.1660 article EN JAMA 2019-03-26

Neonatal endotracheal intubation often involves more than one attempt, and oxygen desaturation is common. It unclear whether nasal high-flow therapy, which extends the time to during elective in children adults receiving general anesthesia, can improve likelihood of successful neonatal on first attempt.

10.1056/nejmoa2116735 article EN New England Journal of Medicine 2022-04-27

Techniques of positioning and holding neonatal face masks vary. Studies have shown that leak at the mask is common often substantial irrespective operator experience.(1) To identify a technique for placement hold which will minimise leak. (2) investigate effect written instruction demonstration identified on two round masks.Three experienced neonatologists compared methods placing to Fisher & Paykel 60 mm Laerdal size 0/1 masks. 50 clinical staff gave positive pressure ventilation modified...

10.1136/adc.2007.117788 article EN Archives of Disease in Childhood Fetal & Neonatal 2007-11-27

Nasal high-flow therapy is an alternative to nasal continuous positive airway pressure (CPAP) as a means of respiratory support for newborn infants. The efficacy in nontertiary special care nurseries unknown.

10.1056/nejmoa1812077 article EN New England Journal of Medicine 2019-05-22

<h3>Background:</h3> Positive pressure ventilation (PPV) via a face mask is an important skill taught using manikins. There have been few attempts to assess the effectiveness of different designs. <h3>Aim:</h3> To determine whether leak at during simulated neonatal resuscitation differed between new round design and current most widely used model. <h3>Method:</h3> 50 participants gave PPV modified manikin designed measure mask. Leak was calculated from difference inspired expired tidal...

10.1136/adc.2007.117713 article EN Archives of Disease in Childhood Fetal & Neonatal 2007-11-27

<h3>Background:</h3> Less invasive techniques of respiratory support are increasingly popular. <h3>Objective:</h3> To determine how widespread the use neonatal nasal intermittent positive airway pressure (NIPPV) has become and describe range practice used in NIPPV England. <h3>Methods:</h3> 95 English Neonatal intensive care units were asked to provide information about devices, interfaces, indications, guidelines, synchronisation, complications, settings weaning. <h3>Results:</h3> 91 (96%)...

10.1136/adc.2007.118109 article EN Archives of Disease in Childhood Fetal & Neonatal 2007-07-18

<h3>Background</h3> Nasal intermittent positive pressure ventilation (NIPPV) may be beneficial but the mechanisms of action are undetermined. <h3>Aim</h3> To investigate effects non-synchronised NIPPV on spontaneous breathing in premature infants. <h3>Methods</h3> 10 infants receiving ventilator generated were studied for 30 min. Delivered was measured at nose; respiration recorded using respiratory inductance plethysmography. Oxygen saturation, carbon dioxide, heart rate, inspired oxygen...

10.1136/adc.2010.205195 article EN Archives of Disease in Childhood Fetal & Neonatal 2011-02-20

Non-tertiary centres (NTCs) in Australia and New Zealand are increasingly providing non-invasive respiratory support, including high-flow nasal cannulae (HFNC) continuous positive airway pressure (nCPAP), to newborn infants. We aimed determine the proportion of NTCs these countries treating infants with HFNC nCPAP, how therapies used.We surveyed public private Zealand. The survey, directed at senior medical nursing staff, consisted questions regarding unit demographics, nCPAP use.One hundred...

10.1111/j.1440-1754.2011.02186.x article EN Journal of Paediatrics and Child Health 2011-10-12

Abstract The imperative to improve the well-being of graduate medical education (GME) trainees has been well documented. While existing interventions have largely centered on increasing individual trainee resilience, less focus role national health policy, economics, and overall U.S. care delivery system in acting as antecedent contributors burnout among learners. To explore impact these level factors, Princeton University hosted Systems Summit Clinical Wellbeing October 2023. Co-sponsored...

10.1097/acm.0000000000005969 article EN cc-by-nc-nd Academic Medicine 2025-01-06

Objective The James Lind Alliance (JLA) Most Premature Babies Priority Setting Partnership aimed to identify the most important areas for research infants born &lt;25 weeks’ gestation. Design Employing standardised JLA methodology, questions were sought from stakeholders via an online survey. Summary formed and checked against existing evidence, with unanswered compiled into a second shortlisting survey prioritisation by stakeholders. A stakeholder consensus workshop was held determine top...

10.1136/archdischild-2024-328133 article EN cc-by-nc Archives of Disease in Childhood Fetal & Neonatal 2025-02-23
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