A5031044762- Wnt/β-catenin signaling in development and cancer
- Cancer-related gene regulation
- Proteoglycans and glycosaminoglycans research
- Cardiovascular Disease and Adiposity
- Adipose Tissue and Metabolism
- Kruppel-like factors research
- Fibroblast Growth Factor Research
- Mitochondrial Function and Pathology
- Polysaccharides Composition and Applications
- Cancer Cells and Metastasis
- Connective tissue disorders research
- Cancer, Lipids, and Metabolism
- Heme Oxygenase-1 and Carbon Monoxide
- Meat and Animal Product Quality
- Adipokines, Inflammation, and Metabolic Diseases
- Cannabis and Cannabinoid Research
- Drug Transport and Resistance Mechanisms
- Cell Adhesion Molecules Research
- Neonatal Health and Biochemistry
- Cancer, Hypoxia, and Metabolism
Istituto Oncologico Veneto
2024
Istituti di Ricovero e Cura a Carattere Scientifico
2024
University of Verona
2017-2022
Sofar (Italy)
2016
University of Modena and Reggio Emilia
2010-2014
Several reports indicate that mesalazine (5-aminosalicylic acid, 5-ASA) is a promising candidate for the chemoprevention of colo-rectal cancer because its ability to reach purpose avoiding unwanted side effects usually associated with prolonged administration nonsteroidal anti-inflammatory drugs. This activity 5-ASA probably consequence number determined on cells, consisting reduced proliferation, increased apoptosis and activation cell cycle checkpoints DNA repair processes. A recent...
Mu-protocadherin (MUCDHL) is an adhesion molecule predominantly expressed by colorectal epithelial cells which markedly downregulated upon malignant transformation. Notably, treatment of cancer (CRC) with mesalazine lead to increased expression MUCDHL, and associated sequestration β-catenin on the plasma membrane inhibition its transcriptional activity. To better characterize causal relationship between MUCDHL expression, we performed various experiments in CRC cell lines normal colonic...
In ovarian cancer, expression of metabolism-related markers has been investigated in several studies focusing on individual markers; however, a parallel quantitative evaluation mapping to distinct metabolic processes and their prognostic value large patient cohorts is still lacking.