- Dental Implant Techniques and Outcomes
- Periodontal Regeneration and Treatments
- Dental Radiography and Imaging
- Bone Tissue Engineering Materials
- Endodontics and Root Canal Treatments
- Dental materials and restorations
- Laser Applications in Dentistry and Medicine
- Oral microbiology and periodontitis research
- Oral and Maxillofacial Pathology
- Dental Trauma and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Oral and gingival health research
- Dental Research and COVID-19
- Diamond and Carbon-based Materials Research
- dental development and anomalies
- Advanced Frequency and Time Standards
- Orthopaedic implants and arthroplasty
- Advanced X-ray and CT Imaging
- Metal and Thin Film Mechanics
- Bone and Dental Protein Studies
- Surface Roughness and Optical Measurements
- Atomic and Subatomic Physics Research
- Radiation Therapy and Dosimetry
- Tribology and Wear Analysis
- Medical Imaging Techniques and Applications
Heinrich Heine University Düsseldorf
2015-2024
Düsseldorf University Hospital
2012-2024
Oerlikon (Germany)
2012-2018
Leibniz University Hannover
2016
Ortenau Klinikum
2012
Physikalisch-Technische Bundesanstalt
2008
Johannes Gutenberg University Mainz
1998-2004
Freudenberg (Germany)
2001-2002
Laser- und Medizin-Technologie (Germany)
1990
University of Kaiserslautern
1989
The aim of the present histologic study was to compare in vivo and vitro effects an erbium: yttrium, aluminum, garnet (Er:YAG) laser (ERL), combined with a fluorescent calculus detection system, diode (DL) scaling root planing (SRP) on periodontally diseased surfaces.Twenty-four single rooted teeth, considered for extraction due severe periodontal destruction, were included study. Prior all mesial surfaces randomly assigned following treatment groups: (1) ERL system fluorescence induced by...
Background: Recent preclinical and clinical data have suggested a potential benefit of photodynamic therapy (PDT) in the treatment periodontitis. However, there are very limited from controlled trials evaluating effect PDT The aim this study was to evaluate microbiologic effects adjunctive use non‐surgical periodontal treatment. Methods: Twenty‐four subjects with chronic periodontitis were randomly treated scaling root planing followed by single episode (test) or alone (control). Full‐mouth...
Abstract: The aim of this controlled, parallel design clinical study was to compare the effectiveness an Er:YAG laser (ERL) that mechanical debridement using plastic curettes and antiseptic therapy for nonsurgical treatment peri‐implantitis. Twenty patients with moderate advanced peri‐implantitis lesions were randomly treated either (1) ERL a cone‐shaped glass fiber tip at energy setting 100 mJ/pulse 10 pps (ERL), or (2) chlorhexidine digluconate (0.2%) (C). following parameters measured...
The aim of the present study was to evaluate biocompatibility differently cross-linked collagen membranes in cultures human PDL fibroblasts and osteoblast-like cells. Four [BioGide (BG), BioMend (BM), Ossix (OS) TutoDent (TD)] were tested. Cells plated on culture dishes (CD) served as positive controls. Six specimens each membrane incubated with (1) [2 x 10(4) cells] (n=24), (2) cells (SaOs-2) (n=24) under standardized conditions. After 7 days, adherent stained hematoxylin counted using a...
Abstract Objectives: The aim of the present study was to evaluate and compare naturally occuring ligature‐induced peri‐implantitis bone defects in humans dogs. Material Methods: Twenty‐four partially fully edentulous patients undergoing peri‐implant augmentation procedures due advanced infections were included this ( n =40 implants). Furthermore, induced by ligature placement plaque accumulation five beagle dogs for three months following implant insertion =15 ligatures removed when about...
Abstract Objectives: The aim of the present pilot study was to investigate initial and early tissue reactions modified (mod) conventional sand‐blasted, large grit acid‐etched (SLA) titanium implants. Material methods: Implantation modSLA SLA implants performed bilaterally in both mandible maxilla dogs. animals were sacrificed after a healing period 1, 4, 7 14 days, respectively. Peri‐implant assessed non‐decalcified sections using histology (Toluidine blue‐TB Masson Goldner Trichrome...
Abstract Objectives: The aim of the present case series was to evaluate healing intrabony peri‐implantitis defects following application a nanocrystalline hydroxyapatite (NHA) or bovine‐derived xenograft in combination with collagen membrane (BDX+BG). Material and Methods: Twenty‐two patients having moderate ( n =22 defects) were randomly treated (i) access flap surgery (AFS) NHA, AFS BDX+BG. Clinical parameters recorded at baseline after 6 months non‐submerged healing. Results:...
Sahm N, Becker J, Santel T, Schwarz F. Non-surgical treatment of peri-implantitis using an air-abrasive device or mechanical debridement and local application chlorhexidine: a prospective, randomized, controlled clinical study. J Clin Periodontol 2011; 38: 872–878. doi: 10.1111/j.1600-051X.2011.01762.x. Objectives: The aim this parallel group designed, randomized study was to evaluate the effectiveness (AAD) for non-surgical peri-implantitis. Material Methods: Thirty patients, each whom...
Abstract Objective: The aim of the present study was to evaluate non‐submerged and submerged healing ligature induced peri‐implantitis in dogs. Material Methods: Peri‐implantitis by placement five beagle dogs ( n =30 implants). defects were randomly equally allocated a split‐mouth design either closed treatment+non‐submerged (CNS), or open treatment+submerged (OS) using an Er:YAG laser (ERL), ultrasonic device (VUS), plastic curettes+local application metronidazole gel (PCM), respectively....
Abstract Objectives: The aim of the present study was to evaluate immunohistochemically pattern guided bone regeneration (GBR) using different types barrier membranes. Material and methods: Standardized buccal dehiscence defects were surgically created following implant bed preparation in 12 beagle dogs. Defects randomly assigned six GBR procedures: a collagen‐coated grafting material (BOC) combination with either native, three cross‐linked, titanium‐reinforced collagen membrane, or expanded...
Abstract Background: Treatment with enamel matrix proteins (EMD) or guided tissue regeneration (GTR) has been shown to enhance periodontal regeneration. However, until now there are limited data on the long‐term results following these treatment modalities. Aim: The aim of present clinical study was 5‐year intrabony defects EMD, GTR, combination EMD and open flap debridement (OFD). Material Methods: Forty‐two patients, each whom displayed one defect a probing depth at least 6 mm, were...
Abstract Objectives: The purpose of the present controlled clinical trial was to compare treatment advanced periodontal disease with a combination an Er:YAG laser (KEY II ® , KaVo, Germany) and scaling root planing hand instruments (SRP) alone. Material methods: Twenty healthy patients moderate destruction were randomly treated in split‐mouth design SRP (test) or (control) used energy setting for 160 mJ/pulse at repetition rate 10 Hz. Prior 3, 6 12 months later following parameters evaluated...
Abstract Studies have indicated that oral biofilm formation at structured titanium surfaces interferes with cell adhesion and proliferation, its removal by means of conventional treatment procedures may not be sufficient to render these biologically acceptable. Therefore, the aim study was evaluate influence different air‐abrasive powders on viability contaminated dental implant surfaces. Intraoral splints were used collect an in vivo sandblasted acid‐etched discs for 48 h. A single (1x)...
The aim of the present study was to immunohistochemically evaluate lateral ridge augmentation using a particulated (BOG) or block (BOB) natural bone mineral biocoated with rhGDF-5 and rhBMP-2 in dogs.Three standardized box-shaped defects were surgically created at buccal aspect alveolar each quadrant eight beagle dogs. After 2 months healing, chronic-type randomly allocated split-mouth design either (i) BOG (ii) BOB (a) (b) rhBMP-2, respectively. Uncoated grafts served as controls. 3 8...
The aim of the present randomized-controlled double-blinded clinical multicenter study was to assess use either a new cross-linked (VN) or native collagen membrane (BG) for treatment dehiscence-type defects at titanium implants.A total n=54 patients were recruited in four German university clinics. According parallel-groups design, implants filled with natural bone mineral and randomly assigned VN BG. Submerged sites allowed heal 4 months. Primary (e.g., changes defect length - DeltaDL,...
To evaluate radiological bone level (RBL) (i.e. cone-beam computed tomography) and histological levels (HBL) as well re-osseointegration [bone-to-implant contact (BIC)] after surgical resective implantoplasty) and/or regenerative therapy of advanced ligature-induced peri-implantitis in dogs.At all defect sites (n=6 dogs, n=48 implants), the intrabony component was filled with a particulate bovine-derived natural mineral (NBM). The supracrestal treated by either application an equine block...
Abstract Objectives To assess and compare the efficacy safety of autogenous tooth roots ( TR ) bone blocks AB for lateral alveolar ridge augmentation two‐stage implant placement. Material Methods A total 30 patients in need therapy were allocated to parallel groups receiving either (a) healthy (e.g. retained wisdom or impacted teeth) n = 15) (b) cortical harvested from retromolar area. After 26 weeks submerged healing, primary endpoint was defined as crestal width (mm) CW 26) being...
Background: The aim of the present study was to compare effectiveness an Er:YAG laser that ultrasonic scaling for non‐surgical periodontal treatment. Methods: Twenty patients with moderate advanced disease were randomly treated in a split‐mouth design single episode subgingival debridement using either device (160 mJ/pulse, 10 Hz) combined calculus detection system fluorescence induced by 655 nm InGaAsP diode radiation (ERL), or instrument (UI). Clinical assessments full‐mouth plaque score...
Abstract: The aim of the present study was to investigate effects an Er : YAG laser (ERL) and Vector ® ultrasonic system (VS) on biocompatibility titanium implants in cultures human osteoblast‐like cells (SAOS‐2). One hundred sixty‐eight discs with four different surfaces (sand‐blasted acid‐etched, plasma‐sprayed, machine‐polished, hydroxyapatite‐coated) were used evaluate cell attachment. samples equally randomly assigned following groups: (1) ERL at energy level 100 mJ/pulse 10 Hz using a...