Abstract: The aim of the present study was to compare biodegradation differently cross‐linked collagen membranes in rats. Five commercially available and three experimental (VN) were included: (1) BioGide ® (BG) (non‐cross‐linked porcine type I III collagens), (2) BioMend (BM), (3) BioMendExtend (BME) (glutaraldehyde bovine collagen), (4) Ossix (OS) (enzymatic‐cross‐linked (5) TutoDent (TD) collagen, (6–8) VN(1–3) (chemical collagens). Specimens randomly allocated unconnected subcutaneous...

Abstract: The aim of this controlled, parallel design clinical study was to compare the effectiveness an Er:YAG laser (ERL) that mechanical debridement using plastic curettes and antiseptic therapy for nonsurgical treatment peri‐implantitis. Twenty patients with moderate advanced peri‐implantitis lesions were randomly treated either (1) ERL a cone‐shaped glass fiber tip at energy setting 100 mJ/pulse 10 pps (ERL), or (2) chlorhexidine digluconate (0.2%) (C). following parameters measured...

The aim of the present study was to evaluate biocompatibility differently cross-linked collagen membranes in cultures human PDL fibroblasts and osteoblast-like cells. Four [BioGide (BG), BioMend (BM), Ossix (OS) TutoDent (TD)] were tested. Cells plated on culture dishes (CD) served as positive controls. Six specimens each membrane incubated with (1) [2 x 10(4) cells] (n=24), (2) cells (SaOs-2) (n=24) under standardized conditions. After 7 days, adherent stained hematoxylin counted using a...

The aim of the present study was to immunohistochemically evaluate angiogenesis pattern native and cross-linked collagen membranes after subcutaneous implantation in rats. Five commercially available three experimental (VN) were included: (1) BioGide (BG), (2) BioMend (BM), (3) Extend (BME), (4) Ossix (OS), (5) TutoDent (TD), (6-8) VN(1-3). Specimens randomly allocated unconnected pouches (n=4) separated surgically on back 40 wistar rats, which divided into five groups (2, 4, 8, 16, 24...

Abstract Objective: The aim of the present study was to evaluate non‐submerged and submerged healing ligature induced peri‐implantitis in dogs. Material Methods: Peri‐implantitis by placement five beagle dogs ( n =30 implants). defects were randomly equally allocated a split‐mouth design either closed treatment+non‐submerged (CNS), or open treatment+submerged (OS) using an Er:YAG laser (ERL), ultrasonic device (VUS), plastic curettes+local application metronidazole gel (PCM), respectively....

Abstract Objectives: The aim of the present study was to evaluate immunohistochemically pattern guided bone regeneration (GBR) using different types barrier membranes. Material and methods: Standardized buccal dehiscence defects were surgically created following implant bed preparation in 12 beagle dogs. Defects randomly assigned six GBR procedures: a collagen‐coated grafting material (BOC) combination with either native, three cross‐linked, titanium‐reinforced collagen membrane, or expanded...

The present study assesses the accuracy of three-dimensional (3D) cone beam CT (CBCT) and intra-oral radiography (CR) in visualizing peri-implant bone compared with histology.26 titanium dental implants were placed dog jaws chronic type vestibular defects. After a healing period 2 8 weeks (n = 12 dogs) animals sacrificed. CBCT scans CR specimen recorded. Dissected blocks prepared, histomorphometric analysis was performed. Both modalities measured twice by two observers histomorphometry...

Abstract Objective: To assess the accuracy of cone‐beam computed tomography (CBCT) in terms buccal bone‐wall configuration and peri‐implant bone defect regeneration after guided (GBR). Material methods: Titanium implants were inserted into standardized box‐shaped defects mandible 12 foxhounds. Defects one side augmented following principle GBR, while other was left untreated. Radiological evaluation performed using CBCT compared with histomorphometrical measurements respective site serving...

Within the last decades, collagen types I and III have been established as a sufficient biomaterial for GBR GTR procedures. They might also be an adequate matrix soft tissue augmentations. However, materials differ significantly regarding resorption time, biodegradation pattern invasion of inflammatory cells. The aim present study was to compare integration native, differently processed cross-linked scaffolds in rats. Four experimental porcine matrices 1.0 mm thickness, developed...

Abstract Aim: The aim of the present study was to investigate influence a new piezoelectric device, designed for harvesting autogenous bone chips from intra‐oral sites, on chip morphology, cell viability and differentiation. Methods: A total 69 samples cortical were randomly gained by either (1) device (PS), or (2) conventional rotating drills (RD). Shape size compared means morphometrical analysis. Outgrowing osteoblasts identified alkaline phosphatase activity (AP), immunhistochemical...

Abstract Objectives: The aim of the present case series was to evaluate 2‐year results obtained following treatment peri‐implantitis lesions using either a nanocrystalline hydroxyapatite (NHA) or natural bone mineral in combination with collagen membrane (NBM+CM). Material and Methods: Twenty‐two patients suffering from moderate ( n =22 intra‐bony defects) were randomly treated (i) access flap surgery (AFS) application NHA, AFS NBM+CM. Clinical parameters recorded at baseline after 12, 18,...

The aim of the present study was to immunohistochemically evaluate lateral ridge augmentation using a particulated (BOG) or block (BOB) natural bone mineral biocoated with rhGDF-5 and rhBMP-2 in dogs.Three standardized box-shaped defects were surgically created at buccal aspect alveolar each quadrant eight beagle dogs. After 2 months healing, chronic-type randomly allocated split-mouth design either (i) BOG (ii) BOB (a) (b) rhBMP-2, respectively. Uncoated grafts served as controls. 3 8...

To evaluate the accuracy of first integrated system for cone-beam CT (CBCT) imaging, dental implant planning and surgical template-aided placement.On basis CBCT scans, a total 54 positions were planned 10 partially edentulous anatomical patient-equivalent models. Surgical guides ordered from manufacturer (SICAT). Two different types guidance assessed: assessment SICAT inherent vendor's titanium sleeves 2 mm internal diameter 5 length utilized pilot drills. The guide NobelGuide implemented...

Barrier membranes are commonly used as part of the dental surgical technique guided bone regeneration (GBR) and often made resorbable collagen or non-resorbable materials such PTFE. While do not provide sufficient mechanical protection covered defect, titanium reinforced need to be removed in a second surgery. Thus, biodegradable GBR pure magnesium might an alternative. In this study (99.95%) membrane has been proven have all necessary requirements for optimal regenerative outcome from both...

Abstract: The aim of the present study was to investigate effects an Er : YAG laser (ERL) and Vector ® ultrasonic system (VS) on biocompatibility titanium implants in cultures human osteoblast‐like cells (SAOS‐2). One hundred sixty‐eight discs with four different surfaces (sand‐blasted acid‐etched, plasma‐sprayed, machine‐polished, hydroxyapatite‐coated) were used evaluate cell attachment. samples equally randomly assigned following groups: (1) ERL at energy level 100 mJ/pulse 10 Hz using a...

The aim of the present study was to investigate bone formation recombinant human morphogenetic protein-2 (rhBMP-2)-biocoated and rhBMP-2-nonbiocoated titanium implants after implantation in dogs. Implantation sand-blasted acid-etched (C), chromosulfuric acid surface-enhanced (CSA), rhBMP-2-biocoated CSA [BMP-A: noncovalently immobilized rhBMP-2 (596 ng/cm2), BMP-B: covalently (819 ng/cm2)] performed both mandible tibia After 4 weeks healing, percentage direct implant contact (BIC) induced...

The aim of the present study was to investigate bone formation recombinant human morphogenetic protein-2 (rhBMP-2)-biocoated and rhBMP-2-nonbiocoated titanium implants after implantation in dogs. Implantation sand-blasted acid-etched (C), chromosulfuric acid surface-enhanced (CSA), rhBMP-2-biocoated CSA [BMP-A: noncovalently immobilized rhBMP-2 (596 ng/cm(2)), BMP-B: covalently (819 ng/cm(2))] performed both mandible tibia After 4 weeks healing, percentage direct implant contact (BIC)...

Abstract The aim of the present study was to evaluate influence plaque biofilm removal on mitochondrial activity human SaOs‐2 osteoblasts grown titanium surfaces. Volunteers wore acrylic splints with structured discs for 72 h build up biofilms ( n = 30). Specimens were randomly instrumented using either (1) an ultrasonic system at two power settings (EMS1, EMS2) + chlorhexidine (CHX), or (2) plastic curettes CHX. Untreated (NC, 10) and sterile (C, served as controls. incubated cells 6 days....