A5085225128- Lipid Membrane Structure and Behavior
- Surfactants and Colloidal Systems
- Spectroscopy and Quantum Chemical Studies
- Protein Structure and Dynamics
- Advancements in Transdermal Drug Delivery
- Polymer Surface Interaction Studies
- Supramolecular Self-Assembly in Materials
- Force Microscopy Techniques and Applications
- Origins and Evolution of Life
- Electrostatics and Colloid Interactions
- Photoreceptor and optogenetics research
- Nuclear Physics and Applications
- Photosynthetic Processes and Mechanisms
- Material Dynamics and Properties
- Phase Equilibria and Thermodynamics
- Nanopore and Nanochannel Transport Studies
- Liquid Crystal Research Advancements
- Lipid metabolism and biosynthesis
- High Temperature Alloys and Creep
- Enzyme Structure and Function
- Ionic liquids properties and applications
- Polydiacetylene-based materials and applications
- X-ray Diffraction in Crystallography
- Luminescence and Fluorescent Materials
- Sphingolipid Metabolism and Signaling
Institut Laue-Langevin
2016-2025
Institut Langevin
2007-2020
Max Planck Institute of Biochemistry
2011
Warsaw University of Technology
2011
University of Florence
2007
CEA Grenoble
2001-2006
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
1996-2006
CEA Paris-Saclay
1996-2006
Laboratoire Léon Brillouin
1997-2006
Université Joseph Fourier
2003-2005
Discs of finite size are a very rare form stable surfactant self-assembly. It is shown that mixing two oppositely charged single-chain surfactants can produce rigid nanodiscs as well swollen lamellar liquid crystals with frozen bilayers. The crucial requirement for obtaining nanodisc self-assembly the use H+ and OH- counterions. These counterions then water lower conductivity to 10 microsiemens per centimeter. In case cationic component excess, dilute solution in thermodynamic equilibrium...
Thylakoid membranes, the universal structure where photosynthesis takes place in all oxygenic photosynthetic organisms from cyanobacteria to higher plants, have a unique lipid composition. They contain high fraction of 2 uncharged glycolipids, galactoglycerolipids mono- and digalactosyldiacylglycerol (MGDG DGDG, respectively), an anionic sulfolipid, sulfoquinovosediacylglycerol (SQDG). A remarkable feature evolution plants is conservation MGDG, SQDG, phosphatidylglycerol (PG), major...
The structure of a bis-urea based reversible polymer is investigated using capillary viscosimetry, infrared spectroscopy, small-angle neutron scattering, and rheology. highly viscoelastic solutions obtained in toluene are due to the formation long rigid fibrillar species. cross section these wires measured shown likely contain two or three molecules per axial repetition unit.
Ternary mixtures of medium-chain fatty alcohols, water and a hydrotrope (such as ethanol), near the immiscibility gap, make stable single phases at constant temperature. Interestingly, in this `pre-ouzo region' these consist two distinct nanoscopic pseudo-phases, one octanol-rich water-rich. This domain composition, which is known to produce strong light scattering separate under ultracentrifugation into phases, has been studied using contrast variation small-angle neutron (SANS) combined...
Understanding adaptation to extreme environments remains a challenge of high biotechnological potential for fundamental molecular biology. The cytosol many microorganisms, isolated from saline environments, reversibly accumulates molar concentrations the osmolyte ectoine counterbalance fluctuating external salt concentrations. Although they have been studied extensively by thermodynamic and spectroscopic methods, direct experimental structural data have, so far, lacking on...
Abstract Membrane systems that naturally occur as densely packed membrane stacks contain high amounts of glycolipids whose saccharide headgroups display multiple small electric dipoles in the form hydroxyl groups. Experimentally, hydration repulsion between glycolipid membranes is much shorter range than zwitterionic phospholipids are dominated by a single large dipole. Using solvent-explicit molecular dynamics simulations, here we reproduce experimentally observed, different...
The structure of asphaltene solutions in toluene was studied by small-angle neutron scattering (SANS) as a function temperature and concentration. Temperature alters solvent quality, flocculation being expected at low temperature. SANS measurements were carried out four different temperatures (from 73 down to 8 °C) for solute (asphaltene) volume fractions Φ ranging from ≃0.3 ∼10%. Asphaltenes found form nanometric aggregates, whose average masses (Mw) radii gyration (RGZ) increased...
In order to elucidate the mode of action lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based ceramide AP, cholesterol, palmitic acid and cholesterol sulfate containing 10 wt% IPM by means neutron diffraction. Our results indicate that affects lamellar assembly in terms bilayer perturbation disordering. Phase segregation occurred, indicating is not likely mix properly with other SC...
This study reports on the low-pressure hydrogen (H2) and deuterium (D2) physisorption processes in nanoporous activated carbon cloth at supercritical temperatures. In-situ small-angle neutron scattering (SANS) is employed as a hydrogen-sensitive method to determine pore-size-dependent isotope-dependent adsorbate densification for different gas pressures up 1 bar. The changes of SANS signal resulting from molecules pore space described by analytical functions resembling slit-like pores....
Archaeal membranes exhibit remarkable stability under extreme environmental conditions, a feature attributed to their unique lipid composition. While it is widely accepted that tetraether lipids confer structural integrity by forming monolayers, the role of bilayer-forming diether in membrane remains unclear. Here, we demonstrate incorporation diethers into archaeal-like assemblies enhances organization and adaptability thermal stress. Using neutron diffraction, show composed mixed...
Archaeal membranes exhibit remarkable stability under extreme environmental conditions, a feature attributed to their unique lipid composition. While it is widely accepted that tetraether lipids confer structural integrity by forming monolayers, the role of bilayer-forming diether in membrane remains unclear. Here, we demonstrate incorporating diethers into archaeal-like assemblies enhances organization and adaptability thermal stress. Using neutron diffraction, show composed mixed...
We study by small angle neutron scattering and UV titration how the ratio of negative to positive charges, [-]/[+](intro), acts on structure complexes formed short negatively charged polyelectrolyte chains (PSS) globular positively proteins (lysozyme). The range [-]/[+](intro) lies between 0.65 3.33. In all ratios, dense primary are with radii around 10 nm. species composition water content precisely obtained systematic use contrast matching (deuterated) polymer or protein in SANS, yielding...
We investigated molecular motions on a picosecond timescale of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) model membranes as function hydration by using elastic and quasielastic neutron scattering. Two different hydrations corresponding to approximately nine twelve water molecules per lipid were studied, the latter being fully hydrated state. In our study, we focused head group chain deuterated lipids. Information in-plane out-of-plane could be extracted solid supported DMPC...
Microgel particles of cross-linked poly(NIPAM-co-acrylic acid) with different acrylic acid contents are investigated in solution and the adsorbed state. As a substrate, silicon poly(allylamine hydrochloride) (PAH) coating is used. The temperature dependence deswelling microgel was probed atomic force microscopy (AFM). inner structure detected grazing incidence small angle neutron scattering (GISANS). Small (SANS) on corresponding suspensions performed for comparison. Whereas correlation...
The radial component is a network of interlamellar tight junctions (TJs) unique to central nervous system myelin. Ablation claudin-11, TJ protein, results in the absence and compromises passive electrical properties Although TJs are known regulate paracellular diffusion, this barrier function has not been directly demonstrated for component, some evidence suggests that may also mediate adhesion between myelin membranes. To investigate physical claudin-11 TJs, we compared fresh, unfixed...
By mixing ionic liquids (ILs), it is possible to fine-tune their bulk and interfacial structure. This alters physical properties solvation behavior a simple way prepare collection of ILs whose can be tuned optimize specific application. In this study, mixtures perfluorinated alkylated have been prepared, links between composition, properties, nanostructure investigated. These different classes vary substantially in the flexibility polarizability chains. Thus, range useful structural property...
We report on the synthesis and structure of silica-filled latex films. The main stage consists physicochemical manipulations colloidal solutions nanosilica nanolatex beads, followed by drying filmification. Hence, no mechanical energy which might contribute to building or destruction aggregates silica beads is supplied samples.We have analyzed resulting filled films means small-angle neutron scattering. scattered intensity varies enormously with parameters, indicating considerable structural...