A5008872538- Natural product bioactivities and synthesis
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Ethnobotanical and Medicinal Plants Studies
- African Botany and Ecology Studies
- Crystallography and molecular interactions
- Antimicrobial agents and applications
- RNA Interference and Gene Delivery
- Antibiotic Resistance in Bacteria
- Advanced biosensing and bioanalysis techniques
- Chemical Synthesis and Analysis
- Bioactive Compounds and Antitumor Agents
- Bioactive natural compounds
- Enzyme Catalysis and Immobilization
- Protein Structure and Dynamics
- SARS-CoV-2 detection and testing
- Supramolecular Chemistry and Complexes
- SARS-CoV-2 and COVID-19 Research
- DNA and Nucleic Acid Chemistry
- Click Chemistry and Applications
- Traditional and Medicinal Uses of Annonaceae
- Pharmacological Effects of Natural Compounds
- Antimicrobial Peptides and Activities
Université Claude Bernard Lyon 1
2020-2025
Centre National de la Recherche Scientifique
2011-2025
Institut National des Sciences Appliquées de Lyon
2020-2025
Laboratoire de Microbiologie, Adaptation et Pathogénie
2019-2024
Université de Lorraine
2008-2021
Laboratoire Lorrain de Chimie Moléculaire
2018
Institut de Recherche sur les Systèmes Atomiques et Moléculaires Complexes
2007-2017
Laboratoire d'Étude des Microstructures et de Mécanique des Matériaux
2017
Délégation Centre-Est
2015
Laboratoire de Chimie Physique et Microbiologie pour l'Environnement
2008
A novel pH- and glutathione-responsive drug delivery system has been developed by deposition of tannic acid (TA)–Fe(<sc>iii</sc>) complex on the surface mesoporous silica nanoparticles (MSN).
(1) Background: Viral respiratory infections cause life-threatening diseases in millions of people worldwide every year. Human coronavirus and several picornaviruses are responsible for epidemic outbreaks, thus representing a heavy burden to their hosts. In the absence specific treatments human viral infections, natural products offer an alternative terms innovative drug therapies. (2) Methods: We analyzed antiviral properties leaves stem bark mulberry tree (Morus spp.). compared activity...
Emergence of multidrug-resistant bacteria has encouraged vigorous efforts to develop antimicrobial agents with new mechanisms action. In this study, the in vitro antibacterial activity para-guanidinoethylcalix[4]arene was evaluated and compared that its constitutive monomer, para-guanidinoethylphenol. Hexamidine, a widely used antiseptic, synthalin A, an old antidiabetic anti-trypanosomal compound, were chosen as references.MIC MBC determined for five reference strains (Escherichia coli ATCC...
The demand for dry juniper (Juniperus communis) needles as a raw material the food, pharmaceutical, and cosmetic industries has increased rapidly in recent years. Juniper are known to be rich terpenoids phenolics, but their chemical composition antibacterial properties have not been well-characterized. In this study, we describe soluble phenolic terpenoid of collected Finland (n = 125) demonstrate that concentration these compounds clearly with latitude altitude with, however, stronger...
Archaeal membranes exhibit remarkable stability under extreme environmental conditions, a feature attributed to their unique lipid composition. While it is widely accepted that tetraether lipids confer structural integrity by forming monolayers, the role of bilayer-forming diether in membrane remains unclear. Here, we demonstrate incorporation diethers into archaeal-like assemblies enhances organization and adaptability thermal stress. Using neutron diffraction, show composed mixed...
Archaeal membranes exhibit remarkable stability under extreme environmental conditions, a feature attributed to their unique lipid composition. While it is widely accepted that tetraether lipids confer structural integrity by forming monolayers, the role of bilayer-forming diether in membrane remains unclear. Here, we demonstrate incorporating diethers into archaeal-like assemblies enhances organization and adaptability thermal stress. Using neutron diffraction, show composed mixed...
The facile synthesis of a novel bis-(guanidinium)-tetrakis-(β-cyclodextrin) tetrapod, the first example new host family, was described, and ability cyclodextrin CyD tetrapod to form molecular association with siRNA DNA guest molecules demonstrated. Affinity capillary electrophoresis used determine binding constant evaluation shift in electrophoretic mobility μ injected when various concentrations were added run buffer. A significant (Ka =16 000 M−1) obtained borate buffer double-stranded...
In Sudan, the roots of Hydnora johannis (Hydnoraceae) are traditionally used for treatment dysentery, diarrhea, cholera and swelling tonsillitis. The ethnomedicinal value H. was investigated through phytochemical study, in vitro antibacterial activity preliminary cytotoxic tests. Determination total phenols, flavonoids proanthocyanidins carried out using spectrometric methods. water ethanolic extracts determined microdilution method. Pure compounds were isolated from ethyl acetate extract by...
<italic>Lactobacillus rhamnosus GG</italic> (LGG) was encapsulated in core–shell alginate–silica microcapsules by coating the electrosprayed ionogel with a silica shell <italic>via</italic> hydrolysis/condensation of alkoxysilane precursors.
Abstract Given the worldwide spread of bacterial drug resistance, there is an urgent need to develop new compounds that exhibit potent antibacterial activity and are unimpaired by this phenomenon. Quaternary ammonium have been used for many years as disinfectants, but recent advances shown polycationic derivatives much stronger less prone resistance than commonly monocationic compounds. In sense, we prepared three series bis‐cationic compounds: bis‐thiazoliums, bis‐imidazoliums,...
It has been shown that diverse strains of bacteria can be separated according to their characteristic surface properties by means CE. We employed here this analytical technique the study colistin‐resistance in Gram‐negative bacteria, which involves selection mutants with modified outer membrane composition resulting changes cell properties. In same way as molecular entities, we performed firstly validation an ITP‐based CE method for three common pathogenic namely Escherichia coli ,...