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Research Areas
- Muscle Physiology and Disorders
- Extracellular vesicles in disease
- Plant Micronutrient Interactions and Effects
- RNA modifications and cancer
- Cellular transport and secretion
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2022
Muscle cell fusion is a multistep process where the final step of reaction drives progression beyond early hemifusion events to complete fusion. This requires activity muscle-specific fusogen Myomerger, single-pass transmembrane protein containing 84 amino acids with an ectodomain that includes two α-helices. Previous studies have demonstrated Myomerger acts by destabilizing membranes through generation elastic stresses in outer leaflet plasma membrane. An obvious question how such might be...
10.1073/pnas.2202490119
article
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cc-by-nc-nd
Proceedings of the National Academy of Sciences
2022-09-12
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