Elliana Malovic Huffman

ORCID: 0000-0002-9533-6230
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About
Contact & Profiles
Research Areas
  • Muscle Physiology and Disorders
  • Extracellular vesicles in disease
  • Plant Micronutrient Interactions and Effects
  • RNA modifications and cancer
  • Cellular transport and secretion

Eunice Kennedy Shriver National Institute of Child Health and Human Development
2022

Muscle cell fusion is a multistep process where the final step of reaction drives progression beyond early hemifusion events to complete fusion. This requires activity muscle-specific fusogen Myomerger, single-pass transmembrane protein containing 84 amino acids with an ectodomain that includes two α-helices. Previous studies have demonstrated Myomerger acts by destabilizing membranes through generation elastic stresses in outer leaflet plasma membrane. An obvious question how such might be...

10.1073/pnas.2202490119 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2022-09-12
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