- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- Neurotransmitter Receptor Influence on Behavior
- Prenatal Substance Exposure Effects
- Pain Mechanisms and Treatments
- Pain Management and Opioid Use
- Cannabis and Cannabinoid Research
- Stress Responses and Cortisol
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- HIV, Drug Use, Sexual Risk
- Behavioral Health and Interventions
- Sleep and related disorders
- Pharmacological Receptor Mechanisms and Effects
- Treatment of Major Depression
- Neuroscience and Neuropharmacology Research
- Cancer Treatment and Pharmacology
- Functional Brain Connectivity Studies
- Sleep and Wakefulness Research
- Pain Management and Placebo Effect
- Healthcare professionals’ stress and burnout
- Forensic Toxicology and Drug Analysis
- Smoking Behavior and Cessation
- Attention Deficit Hyperactivity Disorder
- Mental Health Research Topics
Wayne State University
2016-2025
Eugene Applebaum College of Pharmacy and Health Sciences
2014-2024
The Barbara Ann Karmanos Cancer Institute
2018-2023
Creative Commons
2023
Indivior (United States)
2023
Pioneer (United States)
2023
University of Washington
2023
University of California, San Francisco
2023
University of Massachusetts Chan Medical School
2023
Museum of Art and Design Hamburg
2021-2022
Abstract Colored photographic pictures that varied widely across the affective dimensions of valence (pleasant‐unpleasant) and arousal (excited‐calm) were each viewed for a 6‐s period while facial electromyographic (zygomatic corrugator muscle activity) visceral (heart rate skin conductance) reactions measured. Judgments relating to pleasure, arousal, interest, emotional state measured, as was choice viewing time. Significant covariation obtained between (a) expression judgments (b)...
Incidental memory performance for pictures that varied along the affective dimensions of pleasantness and arousal was assessed. For both an immediate delayed (1 year later) free-recall task, only dimension had a stable effect on performance: Pictures rated as highly arousing were remembered better than low-arousal stimuli. This corroborated in speeded recognition test, which high-arousal materials encoded earlier experiment produced faster reaction times their counterparts. Pleasantness...
Disturbed sleep is observed in association with acute and chronic pain, some data suggest that disturbed shortened enhances pain. We report the first showing, healthy, painfree, individuals, modest reductions of time specific loss rapid eye movement (REM) produces hyperalgesia following morning. Two repeated-measures design protocols were conducted: (1) a sleep-loss protocol 8 hours time-in-bed, 4 0 time-in-bed conditions (2) REM 2 deprivation, non-REM yoked-control conditions. The studies...
A multiple-response analysis of aversive learning was conducted in human subjects. For each subject, two pictorial stimuli were presented--one paired with electric shock. After training, the magnitude acoustic startle eyeblink reflex elicited context shocked picture increased dramatically and significantly larger than for reflexes during nonshocked stimulus. Five different contents tested separate groups: Reflex potentiation pictures rated as pleasant unpleasant. Conditioned responses also...
Prevalence estimates of illicit drug use by teens are typically generated from confidential or anonymous self-report. While data comparing teen self-report with biological measures limited, adult studies identify varying degrees under-reporting.Hair analyses for cocaine, opiates and marijuana were compared to self- parent-reported in a longitudinal cohort >400 high-risk urban parents.Both parents substantially underreported recent cocaine opiate use. However, parents, more likely deny...
Post-bariatric surgery patients are overrepresented in substance abuse treatment, particularly those who have had the Roux-en-Y gastric bypass (RYGB) procedure. The severity of use disorder (SUD; i.e., warranting inpatient treatment) and related consequences necessitate a better understanding variables associated with post-RYGB SUDs. This investigation assessed factors misuse. Post-RYGB (N = 141; at least 24 months postsurgery) completed an online survey assessing hypothesized to contribute...