A5101594367- Cellular Mechanics and Interactions
- RNA Research and Splicing
- RNA regulation and disease
- Cervical Cancer and HPV Research
- Gastrointestinal Tumor Research and Treatment
- Cancer-related Molecular Pathways
- Streptococcal Infections and Treatments
- Platelet Disorders and Treatments
- Gastric Cancer Management and Outcomes
- Molecular Biology Techniques and Applications
- Circular RNAs in diseases
- Reproductive tract infections research
- Endoplasmic Reticulum Stress and Disease
- Ferroptosis and cancer prognosis
- Cell Adhesion Molecules Research
- Hedgehog Signaling Pathway Studies
- Saffron Plant Research Studies
- Toxoplasma gondii Research Studies
- Ubiquitin and proteasome pathways
- Flavonoids in Medical Research
- Cancer, Lipids, and Metabolism
Chongqing Medical University
2019-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023-2024
Sir Run Run Shaw Hospital
2018
Zhejiang University
2018
Osteosarcoma is a primary solid bone malignancy, and surgery + chemotherapy the most commonly used treatment. However, chemotherapeutic drugs can cause range of side effects. Casticin, polymethoxyflavonoid, has anti-tumor therapeutic This study aim to investigate anti-osteosarcoma activity casticin explore mechanism. Crystal violet staining, MTT assay, colony formation wound healing transwell hoechst 33,258 flow cytometry analysis were effects on proliferation, migration, invasion, apoptosis...
Cervical cancer is the 4th highest cause of female reproductive tract malignancies. Multiple loci have been identified as important determinant factors for tumor susceptibility. In this report, we aimed to explore roles gene polymorphisms affecting x-ray repair cross complementing 1 (XRCC1), protein p53 (TP53), and fibroblast growth factor receptor 3 (FGFR3) in context susceptibility cervical cancer. Additionally, assessed impact single nucleotide polymorphism-single polymorphism (SNP-SNP)...
Cervical cancer is the most prevalent gynecological tumor among women worldwide. Although incidence and mortality of cervical have been declining thanks to wide-scale implementation cytological screening, it remains a major challenge in clinical treatment. High viability one leading causes chemotherapeutic resistance cancers. Formin-binding protein 1 (FNBP1) could stimulate F-actin polymerization beneath curved plasma membrane cell migration endocytosis, which had previously well defined....
Background: Osteosarcoma is a highly invasive and early metastatic tumor. At present, the toxic side effects of chemotherapy affect quality life cancer patients to varying degrees. Genipin an extract natural medicine gardenia with various pharmacological activities. Objective: The purpose this study was investigate effect on osteosarcoma its potential mechanism action. Methods: Crystal violet staining, MTT assay colony formation were used detect genipin proliferation osteosarcoma. vitexin...
Abstract Aim Patients with advanced gastrointestinal stromal tumors (GISTs) exhibiting an imatinib plasma trough concentration (IM C min ) under 1100 ng/ml may show a reduced drug response rate, leading to the suggestion of monitoring for IM . Consequently, objective this research was create customized classification model patients GISTs from China. Methods Initial data and laboratory indicators were gathered, above information segmented into training set, validation testing set in 6:2:2...
Deleterious variations in STXBP1 are responsible for early infantile epileptic encephalopathy type 4 (EIEE4, OMIM # 612164) because of its dysfunction the central nervous system. The clinical spectrum neurodevelopmental delays associated with aberrations is collectively defined as (STXBP1-E), conspicuous features which highlighted by early-onset seizures without structural brain anomalies. A girl was first diagnosed unexplained disorders movement and cognition, later developed into STXBP1-E...