Conventional nanozyme technologies face formidable challenges of intricate size-, composition-, and facet-dependent catalysis inherently low active site density. We discovered a new class single-atom nanozymes with atomically dispersed enzyme-like sites in nanomaterials, which significantly enhanced catalytic performance, uncovered the underlying mechanism. With oxidase as model reaction, experimental studies theoretical calculations revealed that carbon nanoframe-confined FeN5 centers (FeN5...

Replacement of precious Pt with earth-abundant electrocatalysts for the hydrogen evolution reaction (HER) holds great promise clean energy devices, but development low-cost and durable HER catalysts Pt-like activity is still a huge challenge. In this communication, we report on self-standing ternary FexCo1–xP nanowire array carbon cloth (FexCo1–xP/CC) as Pt-free catalyst activities being strongly related to Fe substitution ratio. Electrochemical tests show that Fe0.5Co0.5P/CC not only...

A three‐tiered cake‐style composite is elaborately established, with the characteristic of a double‐deck MoS 2 nanosheets and reduction graphene oxide (RGO) sheets dotted CoS nanoparticles (CoS @MoS /RGO). Because prominent synergistic effect acting as conductive support, providing abundant catalytically active sites, structure promoting mechanical stability, /RGO exhibits superior hydrogen evolution reaction activity small overpotential 98 mV at cathodic current density 10 mA cm −2 , Tafel...

Electrodeposited nanoporous Ni(OH)₂@Ni film acts as a Janus electrocatalyst for the hydrogen evolution and oxygen reaction, overall water splitting, exhibiting superior activities exceptional long-term stability. Theoretical calculations show that synergistic electrocatalytic effects of Ni(OH)₂ Ni are responsible high activities.

Abstract Constructing earth‐abundant water splitting electrocatalysts performing platinum‐like activity is promising for the hydrogen economy but still a challenging task. Herein, ultrafine CoMnP nanocrystals confined in amorphous carbon nanosheets are designed and implemented by topological transformation strategy from layer double hydroxide/carbon interconnected structures one single nanosheet. The unique structure favors exposure of active sites enables stronger electronic coupling effect...

Histone chaperones facilitate assembly and disassembly of nucleosomes. Understanding the process how histone associate dissociate from histones can help clarify their roles in chromosome metabolism. Some are intrinsically disordered proteins (IDPs). Recent studies IDPs revealed that recognition biomolecules is realized by flexibility dynamics, challenging century-old structure-function paradigm. Here we investigate binding between chaperone Chz1 variant H2A.Z-H2B developing a structure-based...

The reduction of O2 to solid Li2O2, via the intermediates O2– and LiO2, is desired discharge reaction at positive electrode aprotic Li–O2 batteries. In practice, a plethora byproducts are identified together with Li2O2 have been assigned side reactions between reduced oxygen species (O2–, Li2O2) battery components (the cathode electrolyte). Understanding reactivity these critical for development stable thus high cycle life. readily available, their reactivities studied in depth both...

Volatile radionuclides generated during the nuclear fission process, such as iodine, pose risks to public safety and cause threat of environmental pollution. Covalent organic framework (COF) materials have a controlled pore structure large specific surface area thus demonstrate great opportunities in field radioactive iodine adsorption. However, harsh synthetic conditions weak binding capability toward significantly restricted applications COFs Here, we facile way prepare series stable...

Adenylate kinase (ADK) has been explored widely, through both experimental and theoretical studies. However, still less is known about how the functional dynamics of ADK modulated explicitly by its natural substrates. Here, we report a quantitative study dynamic energy landscape for responding to substrate binding integrating investigations modeling. We make predictions which are in remarkable agreement with single molecule experiments on substrate-bound complex. With our combined models apo...

Biomolecular functions are determined by their interactions with other molecules. recognition is often flexible and associated large conformational changes involving both binding folding. However, the global physical understanding for process still challenging. Here, we quantified intrinsic energy landscapes of biomolecular in terms binding-folding dynamics 15 homodimers exploring underlying density states, using a structure-based model without considering energetic roughness. By quantifying...

A facile synthesis of chiral penicillamine protected Au nanoclusters with different optical properties has been reported. We have for the first time observed reversal CD signals after scaffolds adsorbed onto surface NCs. Such NCs are utilized bioimaging due to their low cytotoxicity and stable fluorescence emission.

Basic evidence is provided for the benefits of using cytosine-rich DNA strands as scaffolds fluorescent silver nanoclusters. The DFT-calculated fluorescence spectra nanoclusters (AgNCs) protected by monomers (dC, dA, dT, and dG) were in good agreement with experimentally obtained (see picture), showing that only use gives As a service to our authors readers, this journal provides supporting information supplied authors. Such materials are peer reviewed may be re-organized online delivery,...

We report a high-yield strategy for the synthesis of very small silver nanoclusters (2 to 5 atoms) formed from conventional salts and scaffolds as high-performance catalysts oxygen reduction reaction (ORR). The work demonstrates that Ag NCs are excellent ORR show great potential in alkaline fuel cells.

Ein klarer Beweis für die Vorteile der Verwendung Cytosin-reicher DNA-Stränge zur Stabilisierung fluoreszierender Ag-Nanocluster wurde erbracht. Die berechneten Fluoreszenzspektren von mit DNA-Monomeren (dC, dA, dT und dG) geschützten Silber-Nanoclustern (AgNCs) stimmten gut den experimentellen Spektren überein (siehe Bild) zeigen, dass nur zu fluoreszierenden NCs führt.

Self-assembled monolayers (SAMs) of 4,4‘-thiobisbenzenethiol (TBBT) can be formed on Au surface spontaneously. The structural characteristics and adsorption behavior TBBT SAMs have been investigated by enhanced Raman scattering (SERS), electrochemical cyclic voltammetry (CV), ac impedance spectroscopy (EIS), atomic force microscopy (AFM). It is demonstrated that adsorbed losing a H atom, forming one Au−S bond, the other mercapto group free at monolayer owing to presence νS-H 2513 cm-1 δC-S-H...