Previous studies demonstrated that the polypeptide diazepam binding inhibitor (DBI) and its receptor, peripheral-type benzodiazepine receptor (PBR), are involved in regulation of steroid biosynthesis one site PBR action resides mitochondria. In present investigation, evidence is presented a functional form also at cell surface. First, was immunolocalized rat testis using biotin-streptavidin peroxidase immunocytochemistry, results revealed exclusively interstitial Leydig cells. Next,...

Previous studies demonstrated that the mitochondrial peripheral-type benzodiazepine receptor (PBR) regulates steroid biosynthesis. In this study we investigate further PBR action by examining its subcellular localization in mouse adrenal gland using anti-peptide antiserum and employing biotin-strep-tavidin peroxidase immunocytochemistry. Results immunostaining exclusively cortex. Within region, however, staining was homogeneously distributed cells of zona glomerulosa, whereas fasciculata...

Abstract Objectives. Bisphenol A (BPA) has been reported that among other male reproductive dys-functions, it can cause marked estrogenic effects including alteration in serum hormones as well testicular lesions exposed animals. This work sought to study the role of gallic acid (GA), a known antioxidant, on BPA-induced oxidative stress adult Wistar rats using hormone analysis, histopathology, and biochemical assays. Methods. Adult were divided into four groups (n=10) control (0.2 ml corn...

Considerable evidence exists to suggest that epidermal growth factor (EGF) influences spermatogenesis directly. The tissue source of this EGF, however, is not yet clear. In study we examine whether the testis itself can serve as a EGF. Gel filtration fractions acid extracted testes exhibited ability displace 125I-EGF from membranes. testicular containing displacement activity coeluted within same range those submandibular gland (SG) mature EGF and prepared in an identical fashion. Next,...

Immunocytochemistry is a compromise between maintaining antigenicity and preserving tissue morphology. In the testis, successful immunostaining results at level of resolution provided by light microscope have been obtained through use either frozen or paraffin sections, although both techniques are fraught with limitations. With freezing, preservation not optimum, whereas embedding, often destroyed. These limitations trivial led to numerous ambiguous in literature. present study we wish...

This work investigated the gonado- somatic index (GI) by weight and volume its relationship with age in greater cane rat raised captivity at Igbesa, a suburb of Agbara Industrial layout Ogun state, Nigeria. The actual weights volumes testes 18 sexually matured male animals, obtained after sacrificing rats, were used to evaluate gonadosomatic indices. results showed that has low investment spermatogenic tissue spermato- zoa having GI 0.053% 0.059% respectively, compared other rodents like...

n this study, the gross morpho-metry and histology of vesicular, prostate bulbourethral glands were investigated in ten male greater cane rats (Thryonomys swin-derianusTemminck) bred raised captivity at Igbesa, Ogun state, Nigeria. The results showed that cranial lobes vesicular divergent with branches caudal opened separately into urethra. ampulla ductus deferens was absent. Most secretory cells gland have round, basally located nuclei prominent nucleoli poorly stained cytoplasm....

Morphology of the uterus and mammary glands were studied in sexually matured female African giant rat.The was identified as being duplex, having two separate uterine horns cervices.The cervices partially fused separated by a mid-saggital septum.Their thick musculatures projected caudally into vagina portio vaginalis uteri.The results also showed that eight glands, distributed along lateral aspects thoracic inguinal regions, present.The regions had four each arranged pairs cranial caudal...

Se efectuo un estudio morfometrico en 20 encefalos frescos, congelados de ovejas enanas del Oeste africano. El peso promedio cerebro fue 69.14g, mientras que el largo y la altura fueron 7.48cm 4.17cm, respectivamente. La longitud cerebelo 5.08cm 2.27cm, relativo encefalo 0,08%, cabeza 0.8%. Hubo diferencias significativas (p< 0.05) cabeza, encefalo, los animales mas 10kg, si estos son comparados con menor peso. Los valores primeros cuatro parametros altos, cambio quinto bajo. Animales ano...

The aim of this study was to describe the distribution smooth muscle actin and desmin immunopositive cells in ovary giant rat. In addition, describes morphological changes species during oestrous cycle. Healthy secondary tertiary follicles dominated pro-oestrus oestrus. theca externa for actin, but immunonegative desmin. Oestrus also characterized by presence corpora haemorrhagica, which had an outer layer cells. Differentiating lutea were observed metoestrus. A further notable feature...

The present study examines the structure and ultrastructure of bulbourethral glands in 10 sexually matured male greater cane rats raised captivity. Following anaesthesia, were perfusion-fixed transcardially dissected out. Upon morphologic morphometric analysis, Cowper's observed to have an average volume 0.24±0.08 ml, a diameter 6.3±0.6 mm weighs 0.199±0.06 g. paired, gourd-shaped tubuloalveolar surrounded by dense connective tissues separated into lobules capsular septae. Each lobule...

This study reveals the structure, ultrastructure and immunoexpression of oestrogen alpha beta receptors (ERα ERβ) in coagulating glands greater cane rat. Gland samples from 15 adult male rats were processed for histological ultrastructural studies while immunohistochemistry was also carried out. Coagulating gland rat is a paired, triangularly shaped, transparent weighing about 1 ± 0.48 g. Histologically, each secretory acinus composed folded mucosa surrounded by fibromuscular stroma. The...

Testicular samples were collected from African sideneck turtles (Pelusios castaneus) at the peak of spermiogenesis in order to describe spermatid acrosomal vesicle formation and nuclear morphogenesis. Acrosomal commences with a Golgi transport attaching round spermatid, followed by emergence an acrosome granule. This is development sub-acrosomal space, which becomes enlarged as elongation condensation continue. The elongates emerging elongating successively surrounded circular, longitudinal...

The current upsurge in intensive farming practices of greater cane rat has not only lead to higher growth rate but is accompanied by increased fat deposition especially the males. This study attempts characterize one most commonly used estimation parameter, body mass index (BMI) as well evaluates its relationship with testicular and hormonal parameters seventy-two sexually active male rats over a period year. Six animals, kidded raised farm, known ages were each month. experimental protocols...