A5003907890- Phytochemistry and Biological Activities
- Drug-Induced Hepatotoxicity and Protection
- Natural Antidiabetic Agents Studies
- Ethnobotanical and Medicinal Plants Studies
- Essential Oils and Antimicrobial Activity
- Toxin Mechanisms and Immunotoxins
- Malaria Research and Control
- Phytochemicals and Antioxidant Activities
- Moringa oleifera research and applications
- Pharmacological Effects of Medicinal Plants
- Traditional and Medicinal Uses of Annonaceae
- Bioactive Compounds and Antitumor Agents
- Sesquiterpenes and Asteraceae Studies
- Natural product bioactivities and synthesis
- Advances in Cucurbitaceae Research
- Heavy Metals in Plants
- Rabbits: Nutrition, Reproduction, Health
- Liver Disease Diagnosis and Treatment
- Ginger and Zingiberaceae research
- Curcumin's Biomedical Applications
- Transgenic Plants and Applications
- Pharmacological Effects of Natural Compounds
- Plant chemical constituents analysis
- Hepatitis B Virus Studies
- Antioxidant Activity and Oxidative Stress
CUNY School of Law
2025
McPherson University
2024
Covenant University
2014-2024
University of Ibadan
2017
Lagos State Polytechnic
2015
Kunming Institute of Botany
2009-2011
Chinese Academy of Sciences
2009-2011
Federal University of Agriculture
2009
Curcuma longa, popularly known as Turmeric, is a rhizomatous herbaceous perennial plant used in folk medicine for the treatment, prevention, and management of various illnesses such cancer, diabetes, Arthritis, diarrhoea, inflammation, psoriasis, hepatobiliary diseases, gastric peptic ulcers. This study reviewed ethnomedicinal potentials, phytochemicals, pharmacological activities C. longa. In vitro vivo studies reported that longa its major bioactive constituent (curcumin) possess...
Ageratum conyzoides has been used in folklore for the treatment of a wide range diseases. In present investigation, vitro activity ethanol, petroleum ether, ethylacetate, butanol, and water extracts A. were screened some cancer cell lines using sulphorhodamine B (SRB) assay. These include: Human non-small lung carcinoma (A-549), human colon adenocarcinoma (HT-29), gastric (SGC-7901), golima (U-251), breast (MDA-MB-231), prostate (DU-145), hepatic (BEL-7402), mouse leukemia (P-388) lines....
Abstract BACKGROUND A significant number of kidney transplant recipients have low BMD. We hypothesized that calcitriol administration over the first year post-transplantation would protect cortical skeleton in managed without corticosteroids by suppressing PTH and bone remodeling. METHODS In this double-blind, placebo-controlled trial, 67 participants aged ≥18 years on corticosteroid-sparing immunosuppressive regimen were randomized to daily 0.5 mcg or placebo for 12 months after...
The effects of Commiphora africana ethanolic leaf extract on some biochemical markers liver and kidney functions were investigated in rats. results showed a significant (p 0.05) change alkaline phosphatase activity, while groups administered 100 150 mg kg-1 increase. group 25 (p<0.05) increase serum creatinine after 24 h treatment. the histology that there was no noticeable damage to tissues rats extract. However, hydropic degeneration cortical-tubular epithelium glomerulus seen with kg-1....
The nutritional potentials of three medicinal plant parts used by pregnant women in the western part Nigeria Parinari polyandra, Blighia sapida and Xylopia aethiopica were evaluated through their proximate compositions as well percentage mineral elements composition. was high in crude fibre (44.09±2.20%) compared with polyandra that 4.21±1.10% and 12.14±0.70% respectively. Moisture contents were 16.04±1.25% 10.17±2.60% respectively while 30.65±5.02%. total ash contents 2.53±1.20%,...
Chromolaena odorata (L.) King and Robinson (Asteraceae: Eupatorieae) is an invasive perennial weedy scrambling shrub of neotropical origin, widely acknowledged as a major economic ecological burden to many tropical subtropical regions the world including Nigeria. Here, we examine invasion management C. in Nigeria over last seven decades using historical records field surveys ask: (i) Does usefulness influence its success? (ii) Is coordinated control approach against needed face or do need...
Malaria eradication globally is yet to be achieved and transmission sustained in many endemic countries. Plasmodium falciparum continues develop resistance currently available anti-malarial drugs, posing great problems for malaria elimination. This study evaluates the frequencies of asymptomatic infection multidrug resistance-1 (mdr-1) gene mutations parasite isolates, which form basis understanding persistently high incidence South West, Nigeria.A total 535 individuals aged from 6 months...
Abstract This article explores the potential of a specific functional food mix containing lycopene, pigment found in tomatoes, for its role cervical cancer prevention and treatment. The assesses cytotoxic effects on cells conducts molecular docking analysis to understand biological activities binding interactions lycopene. formulations are analysed their phytochemical profile, vitro antioxidant evaluated using spectrophotometric methods. Cytotoxicity tests demonstrate that ethanol extract...
This study was conducted to evaluate the safety potential of leaf extract Ageratum conyzoides Linnaeus in Sprague Dawley (SD) rats using biochemical, haematological and histological indices toxicity. Four groups seven male SD per group were used for study. To A administered 0.25% CMC-Na/kg body weight as control group, while B, C D respectively with 500, 1000 1500 mg/kg ethanolic A. by gastric intubation 14 days. Animals subsequently anaesthetized, blood samples collected biochemical assays;...
Medicinal plants have been documented over the years to play vital role in promoting human health. The study evaluated anti-inflammatory and anti-oxidant activities of different fractions isolated compound from Ricinodendron heudelotii leaves. leaves were extracted with ethanol further partitioned sequentially using petroleum ether, ethylacetate butanol. Bioassay–guided fractionation fraction was done repeated column chromatographic technique while structural elucidation pure carried out...
This study was designed to explore the in vitro anticancer effects of bioactive compounds isolated from Ricinodendron heudelotii on selected cancer cell lines. The leaves plant were extracted with ethanol and partitioned sequence petroleum ether, ethyl acetate, n-butanol. acetate fraction phytochemically studied using thin layer chromatography (TLC) column (CC). Structural elucidation pure obtained done mass spectra, 1H-NMR, 13C-NMR analysis. subsequently screened five different lines:...
Tapinanthus cordifolius an African mistletoe is important medicinal plant that has been shown to lower postprandial hyperglycemia. It proposed mistletoe's hypoglycemic effects are related its ability blood glucose levels and the anti-diabetic activity of some these parasitic plants might be due their block action alpha-amylase. To identify prospective alpha-amylase inhibitors for drug discovery, current study used in vitro experiments computational methods such as molecular docking,...
Precocene II (6,7-dimethoxy-2,2-dimethyl-2-chromene) was the main constituent isolated from Ageratum conyzoides L. and reportedly possessed antifungal activity. The study investigated isolation, purification toxicological effects of precocene A. in Sprague Dawley rats. petroleum ether fraction plant structure determined by 1 H-, 13 C-,DEPT-NMR MS spectral techniques. Three groups eight rats per group were used for study. While B C respectively administered with 25 50 mg/kg 0.25% CMC-Na 11...
Aim: This study was conducted to investigate the effects of leaf extract Citrullus lanatus on carbon tetrachloride (CCl4) induced liver damage in rats. Methodology: Hepatoprotective using five groups (A-E) six male rats per group. Groups A and B served as control were respectively administered with distilled water CCl4 olive oil while C, D E were administered respectively 500, 1,000 1,500mg/kg body weight ethanolic leaf C. lanatus for 7 days. Animals subsequently anaesthetized,...
The burden of hypertension, a silent killer, continues to increase in low- and middle-income countries. This study evaluated blood pressure (BP) healthy adults determine their risk developing hypertension reduce associated morbidity the disease. Overall, 182 subjects aged >16 years participated study. Systolic (SBP) diastolic (DBP) was measured after resting period using mercury sphygmomanometer. Random glucose (RBG) concentration also determined. Regression models were used high BP with...