Ebrahim Shakiba

ORCID: 0000-0002-9603-4293
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About
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Research Areas
  • Nutritional Studies and Diet
  • Liver Disease Diagnosis and Treatment
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Obesity, Physical Activity, Diet
  • HIV/AIDS Research and Interventions
  • Pregnancy and preeclampsia studies
  • COVID-19 epidemiological studies
  • HIV, Drug Use, Sexual Risk
  • COVID-19 Clinical Research Studies
  • Iron Metabolism and Disorders
  • Blood Pressure and Hypertension Studies
  • Diet, Metabolism, and Disease
  • Nutrition and Health in Aging
  • Diet and metabolism studies
  • SARS-CoV-2 and COVID-19 Research
  • Global Public Health Policies and Epidemiology
  • Protease and Inhibitor Mechanisms
  • Paraoxonase enzyme and polymorphisms
  • Fatty Acid Research and Health
  • Folate and B Vitamins Research
  • Chronic Disease Management Strategies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Adipokines, Inflammation, and Metabolic Diseases
  • Health Promotion and Cardiovascular Prevention
  • Acne and Rosacea Treatments and Effects

Kermanshah University of Medical Sciences
2016-2025

Shiraz University of Medical Sciences
2021

Hamedan University of Medical Sciences
2014-2019

Abstract Background Gastroesophageal reflux disease (GERD) in the long term reduces quality of life, leading to digestive diseases. The present study aims determine risk factors for GERD. Method This was conducted on 9,631 adults aged 35–65 years. demographic characteristics, behavioral habits, nutritional intake, physical activity, anthropometric indices, and GERD data were extracted from databank related Ravansar non-communicable diseases (RaNCD). Statistical analysis performed using...

10.1186/s12876-024-03143-9 article EN cc-by BMC Gastroenterology 2024-02-05

Unhealthy dietary patterns are the most important changeable risk factors for breast cancer. The aim of this study was to assess relationship between and cancer among under-50 year women in west Iran.All under 50 years old with pathologically confirmed 2013 2015 who were referred oncology clinics Iran, 408 other outpatient without or cancers at time 2 later selected as control group. data collected using middle-aged periodical care form Iranian Ministry Health analyzed univariate...

10.4178/epih.e2019003 article EN cc-by Epidemiology and Health 2019-01-24

Abstract Background Smoking is the most preventable cause of chronic diseases such as cardiovascular disease (CVD). Dyslipidemia also an important risk factor for CVD. Yet, research has provided contradicting findings regarding association between smoking and blood lipids. This paper examines relationship dyslipidemia based on results a cross-sectional sample Kurdish population in western Iran. Methods population-based study was derived from recruitment phase Ravansar Non-Communicable...

10.1186/s12889-020-08809-z article EN cc-by BMC Public Health 2020-05-13

Abstract Background Visceral adiposity index (VAI) and atherogenic of plasma (AIP) are relatively new indicators for predicting non-communicable diseases (NCDs). Therefore, the present study was done to assess association AIP VAI with risk cardiovascular (CVDs). Methods This cross-sectional conducted on 7,362 individuals aged between 35 65 years old participated in Ravansar (RaNCD) cohort study. calculated based levels triglyceride high -density lipoprotein cholesterol (HDL-C). using values...

10.1186/s12944-021-01505-w article EN cc-by Lipids in Health and Disease 2021-08-01

Insulin resistance (IR) and obesity are risk factors for hypertension; triglyceride-glucose (TyG) is known as a surrogate IR. The present study investigated the association between body mass index (TyG-BMI) of hypertension in Iranian adults.This was conducted on sample 8,610 participants from baseline phase Ravansar non- communicable diseases (RaNCD) Iran. A logistic regression model used to evaluate relationship TyG-BMI hypertension. Receiver operating characteristic (ROC) curve analysis...

10.1186/s12902-023-01411-5 article EN cc-by BMC Endocrine Disorders 2023-07-21

Abstract Hypertension is a public health issue in Iran. The study aimed to estimate the prevalence, awareness, treatment, and control of hypertension, explore their determinants among 10,040 Kurdish adults from Ravansar Non-Communicable Disease (RaNCD) cohort Univariate, multivariate analyses were used for statistical analysis. Prevalence hypertension was 15.7%. Among hypertensive patients, 80.7%, 73.2%, 53.3%, respectively. In analysis, significant associations found between awareness...

10.1038/s41598-019-48232-y article EN cc-by Scientific Reports 2019-08-27

Background . 10-20% of pregnancies end due to spontaneous abortions. In recent years, nondocumentary evidence has been indicative an increase in the prevalence nonspontaneous abortions Iran, especially Kurdish regions. The aim this study is assess lifetime and factors affecting abortion women 35-65 years old. Method Data from recruitment phase Ravansar Non-Communicable Disease (RaNCD) cohort was used. All 4831 married old with history pregnancy were included study. order determine ratio,...

10.1155/2020/4871494 article EN cc-by Journal of Pregnancy 2020-04-27

There is no report on the serial interval (SI) of coronavirus disease 2019 (COVID-19) in Iran, present aims to estimate SI and time-varying R COVID-19 western Iran. In this study, there were 1477 confirmed, probable suspected cases severe acute respiratory syndrome 2 for Kermanshah from 22 February 9 April. The close contacts confirmed identified using telephone follow up patients their contacts. distribution was used as an alternative. We fitted different models clinical onset dates with...

10.1016/j.nmni.2020.100715 article EN cc-by-nc-nd New Microbes and New Infections 2020-06-14

Self-rated health is related to the reduction of burden diseases and outcomes. Various factors affect self-rated health. This study aimed investigate mediating role life style in relationship between literacy In 2023, 495 people aged 18–65 participated this cross-sectional study. Montazeri et al.'s questionnaire, Eshaghi healthy assessment (SRH) questionnaire developed by World Health Organization were used. The structural equation modeling (SEM) was Statistical analysis data performed using...

10.1038/s41598-024-79835-9 article EN cc-by-nc-nd Scientific Reports 2025-01-02

Colorectal cancer (CRC), which is among the most prevalent cancers worldwide, caused by environmental and genetic factors. It has been shown that p53 gene associated with CRC pathogenesis; moreover, Zyxin (ZYX) may play a role in level activity. Therefore, present research aimed to investigate levels of P53 ZYX genes proteins tumor samples. Cancerous tissues (n=31) matched non-cancerous were randomly obtained from 31 patients CRC. Total RNA was extracted using RNXplus, expressions assessed...

10.22088/ijmcm.bums.14.1.462 article EN PubMed 2025-01-01

Systemic lupus erythematosus (SLE) is an autoimmune disease that involves multiple organs and characterized by persistent systemic inflammation. Among the effects of inflammatory mediators, induction matrix metalloproteinases-2 -9 (MMP-2 MMP-9) oxidative stress has been demonstrated to be important in development SLE. In this study, possible association between MMP-9 MMP-2 functional promoter polymorphism, stress, markers with severe cardiovascular (CVD), high blood pressure (HBP),...

10.1177/0961203314559085 article EN Lupus 2014-11-21

There are some evidences indicating DNA damage by oxidant and mutant agents has an essential role in the chronic renal failure end stage disease (ESRD). To investigate possible association of GSTs variants with ESRD, we investigated frequency GST- T1, M1, P1 genotypes, level malondialdehyde (MDA) patients ESRD.The present case-control study consisted 136 ESRD treated maintenance hemodialysis 137 gender- age-matched, unrelated healthy controls from population west Iran. The genotypes were...

10.1080/0886022x.2016.1214054 article EN cc-by-nc Renal Failure 2016-08-08

Abstract The aim of this study was to assess the association between dietary inflammatory index (DII) and non-invasive markers liver status in adults. This cross-sectional performed on 8520 adults, recruited Ravansar Non-Communicable Diseases (RaNCD) cohort study, western Iran. DII score calculated based participants’ intakes obtained from Food Frequency Questionnaire (FFQ). Fatty Liver Index (FLI) by anthropometric measurements some status. Linear regression models were applied estimate...

10.1038/s41598-021-98685-3 article EN cc-by Scientific Reports 2021-11-19

Chronic hyperglycemia activates the inflammatory pathways and oxidative stress mechanisms with consequent damage to nerve tissue retina. The Keap1-Nrf2 pathway acts as one of most important antioxidant organism. Variants Keap1 could affect susceptibility diabetes its complications.In a case-control study, 400 individuals included type 2 mellitus (T2DM) patients without complication, neuropathy, retinopathy, healthy were investigated. levels glutathione (GSH), peroxidase (GPx),...

10.1002/jcla.24163 article EN cc-by Journal of Clinical Laboratory Analysis 2021-12-03

Abstract The prevalence of type 2 diabetes mellitus (T2DM) is increasing in middle- and low-income countries, this disease a burden on public health systems. Notably, dietary components are crucial regulatory factors T2DM. Plant-based patterns certain food groups, such as whole grains, legumes, nuts, vegetables, fruits, inversely correlated with incidence. We conducted the present study to determine association between adherence plant-based diet risk among adults. cross-sectional,...

10.1038/s41598-024-52946-z article EN cc-by Scientific Reports 2024-02-15

Matrix metalloproteinase-2 (MMP-2) is a zinc dependent endonuclease that degrades type IV collagen, the major structural component of basement membranes. MMP-2 functional promoter polymorphism G1575A affects circulating level and may be considered an important genetic determinant cardiovascular disease (CVD) in systemic lupus erythematosus (SLE) patients. In this study, association between 1575A allele with serum MMP-2, neopterin lipid-lipoprotein levels SLE developing CVD was investigated....

10.1177/0961203312436857 article EN Lupus 2012-02-09

Abstract Background Smoking is a social epidemic and one of the main risk factors for premature deaths disabilities worldwide. In present study, we investigated Pattern Cigarette Smoking: intensity, cessation, age beginning. Methods Data collected from recruitment phase Ravansar (a Kurd region in western Iran) Non-Communicable Disease (RaNCD) cohort study was analyzed by using Chi-square test, univariate multivariate logistic regressions, Poisson regression, linear regression. Results...

10.1186/s13011-020-00324-z article EN cc-by Substance Abuse Treatment Prevention and Policy 2020-10-27
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