A5059156388- Multisensory perception and integration
- Visual perception and processing mechanisms
- Olfactory and Sensory Function Studies
- Neural dynamics and brain function
- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Neuroscience and Music Perception
- Tactile and Sensory Interactions
- Color perception and design
- Memory and Neural Mechanisms
- Biochemical Analysis and Sensing Techniques
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Advanced Chemical Sensor Technologies
- Neurobiology of Language and Bilingualism
- Vestibular and auditory disorders
- Categorization, perception, and language
- Memory Processes and Influences
- Advanced Neuroimaging Techniques and Applications
- Reading and Literacy Development
- Neurological disorders and treatments
- Face Recognition and Perception
- Spatial Neglect and Hemispheric Dysfunction
- Electrical and Bioimpedance Tomography
- Zebrafish Biomedical Research Applications
Otto-von-Guericke University Magdeburg
2013-2023
Center for Behavioral Brain Sciences
2013-2023
Leibniz Institute for Neurobiology
2021
Klinikum Magdeburg
2013
University College London
2005-2010
University Hospital Magdeburg
2002-2009
National Hospital for Neurology and Neurosurgery
2005-2008
Leipzig University
2008
The brain should integrate related but not unrelated information from different senses. Temporal patterning of inputs to modalities may provide critical about whether those are or not. We studied effects temporal correspondence between auditory and visual streams on human activity with functional magnetic resonance imaging (fMRI). Streams flashes irregularly jittered, arrhythmic timing could appear right left, without a stream tones that coincided perfectly when present (highly unlikely by...
Combining information across modalities can affect sensory performance. We studied how co-occurring sounds modulate behavioral visual detection sensitivity ( d′ ), and neural responses, for stimuli of higher or lower intensity. Co-occurrence a sound enhanced human lower- but not higher-intensity targets. Functional magnetic resonance imaging (fMRI) linked this to boosts in activity-levels sensory-specific auditory cortex, plus multisensory superior temporal sulcus (STS), specifically...
Humans constantly learn in the absence of explicit rewards. However, neurobiological mechanisms supporting this type internally-guided learning (without feedback) are still unclear. Here, participants who completed a task which no external reward/feedback was provided, exhibited enhanced fMRI-signals within dopaminergic midbrain, hippocampus, and ventral striatum (the SN/VTA-Hippocampal loop) when successfully grasping meaning new-words. Importantly, new-words that were better remembered...
Dopamine release in cortical and subcortical structures plays a central role reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral cognitive operations necessary obtain prospective reward. Here, we provide evidence from human fMRI that can also be mediated by task-demand-related processes thus extends beyond situations only entail extrinsic motivating factors. Using visual discrimination task which...
In everyday life our brain often receives information about events and objects in the real world via several sensory modalities, because natural stimulate more than one sense. These different types of are processed along sensory-specific pathways but finally integrated into a unified percept. During last years studies provided compelling evidence that neural basis multisensory integration is not restricted to higher association areas cortex can already occur at low-level stages cortical...
We recently provided evidence that an intrinsic reward-related signal—triggered by successful learning in absence of any external feedback—modulated the entrance new information into long-term memory via activation dopaminergic midbrain, hippocampus, and ventral striatum (the SN/VTA-Hippocampal loop; Ripollés et al., 2016). Here, we used a double-blind, within-subject randomized pharmacological intervention to test whether this process is indeed dopamine-dependent. A group healthy...
In everyday life our brain often receives information about events and objects in the real world via several sensory modalities, because natural stimulate more than one sense. These different types of are processed along sensory-specific pathways, but finally integrated into a unified percept. During last years, studies provided compelling evidence that neural basis multisensory integration is not restricted to higher association areas cortex, can already occur at low-level stages cortical...
Learning the associations between words and meanings is a fundamental human ability. Although language network cortically well defined, role of white matter pathways supporting novel word-to-meaning mappings remains unclear. Here, by using contextual cross-situational word learning, we tested whether learning meaning new related to integrity language-related in 40 adults (18 women). The arcuate, uncinate, inferior-fronto-occipital inferior-longitudinal fasciculi were virtually dissected...
One major problem for cognitive neuroscience is to describe the interaction between stimulus and task driven neural modulation. We used fMRI investigate this in human brain. Ten male subjects performed a passive listening semantic categorization factorial design. In both tasks, words were presented auditorily at three different rates. found: (i) as word presentation rate increased hemodynamic responses bilaterally superior temporal gyrus including Heschl's (HG), planum temporale (PT), polare...
Philosophers, psychologists, and neuroscientists have long been interested in how the temporal aspects of perception are represented brain. In present study, we investigated neural basis synchrony/asynchrony for audiovisual speech stimuli using functional magnetic resonance imaging (fMRI). Subjects judged relation (a)synchronous streams, indicated any changes their over time. Differential hemodynamic responses synchronous versus asynchronous were observed multisensory superior sulcus complex...
Abstract This study investigated the neural substrates of preserved visual functioning in a patient with homonymous hemianopsia and Riddoch syndrome after posterior cerebral artery stroke affecting primary cortex (area V1). The limited abilities this included above‐chance verbal reports movement color change as well discrimination direction hemianopic field. Functional magnetic resonance imaging showed that motion color‐change stimuli presented to field produced activation several...
Background The superior colliculus (SC) has been shown to play a crucial role in the initiation and coordination of eye- head-movements. knowledge about function this structure is mainly based on single-unit recordings animals with relatively few neuroimaging studies investigating eye-movement related brain activity humans. Methodology/Principal Findings present study employed high-field (7 Tesla) functional magnetic resonance imaging (fMRI) investigate SC responses during endogenously cued...
Abstract Faces expressing fear may attract attention in an automatic bottom–up fashion. Here we address this issue with magneto-encephalographic (MEG) recordings subjects performing a demanding visual search combined the presentation of irrelevant neutral or fearful faces. The impact faces' emotional expression on attentional selection was assessed by analyzing N2pc component—a modulation event-related magnetic field response known to reflect focusing search. We observed that lateralized...