A5000009814- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- Visual perception and processing mechanisms
- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Memory and Neural Mechanisms
- Multisensory perception and integration
- Decision-Making and Behavioral Economics
- Olfactory and Sensory Function Studies
- Behavioral Health and Interventions
- Attention Deficit Hyperactivity Disorder
- Face Recognition and Perception
- Color perception and design
- Neural Networks and Applications
- Behavioral and Psychological Studies
- Stress Responses and Cortisol
- Neurotransmitter Receptor Influence on Behavior
- Experimental Behavioral Economics Studies
- Cognitive Abilities and Testing
- Cardiovascular Syncope and Autonomic Disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Heart Rate Variability and Autonomic Control
- Receptor Mechanisms and Signaling
- Transcranial Magnetic Stimulation Studies
- Nicotinic Acetylcholine Receptors Study
Ghent University
2016-2025
Ghent University Hospital
2013-2024
Duke University
2010-2017
Leibniz Institute for Neurobiology
2006-2012
Otto-von-Guericke University Magdeburg
2010-2012
University Hospital Magdeburg
2012
University College London
2007
National Hospital for Neurology and Neurosurgery
2007
York University
2006
University of Iowa
2006
Response inhibition is essential for navigating everyday life. Its derailment considered integral to numerous neurological and psychiatric disorders, more generally, a wide range of behavioral health problems. Response-inhibition efficiency furthermore correlates with treatment outcome in some these conditions. The stop-signal task an tool determine how quickly response implemented. Despite its apparent simplicity, there are many features (ranging from design data analysis) that vary across...
The spatial focus of attention has traditionally been envisioned as a simple gradient enhanced activity that falls off monotonically with increasing distance. Here, we show high-density magnetoencephalographic recordings in human observers the is not monotonic but instead contains an excitatory peak surrounded by narrow inhibitory region. To demonstrate this center-surround profile, asked subjects to onto color pop-out target and then presented probe stimuli at various distances from target....
Reward has been shown to promote human performance in multiple task domains. However, an important debate developed about the uniqueness of reward-related neural signatures associated with such facilitation, as similar patterns can be triggered by increased attentional focus independent reward. Here, we used functional magnetic resonance imaging directly investigate commonalities and interactions between anticipation both reward difficulty, independently manipulating these factors a...
Anticipating a potential benefit and how difficult it will be to obtain are valuable skills in constantly changing environment. In the human brain, anticipation of reward is encoded by Anterior Cingulate Cortex (ACC) Striatum. Naturally, rewards have an incentive quality, resulting motivational effect improving performance. Recently has been proposed that upcoming task requiring effort induces similar mechanism as reward, relying on same cortico-limbic network. However, this overlapping...
Visual awareness has been proposed to depend on recurrent processing in early visual cortex areas including the primary (V1). Here, we address this hypothesis with high spatiotemporal resolution magnetoencephalographic recordings subjects performing a substitution masking paradigm. Neural activity reflecting is assessed by directly comparing neuromagnetic response elicited effectively and ineffectively masked targets after proportion of trials leading was individually adjusted match without...
Combining information across modalities can affect sensory performance. We studied how co-occurring sounds modulate behavioral visual detection sensitivity ( d′ ), and neural responses, for stimuli of higher or lower intensity. Co-occurrence a sound enhanced human lower- but not higher-intensity targets. Functional magnetic resonance imaging (fMRI) linked this to boosts in activity-levels sensory-specific auditory cortex, plus multisensory superior temporal sulcus (STS), specifically...
It is commonly accepted that reward an effective motivator of behavior, but little known about potential costs resulting from associations. Here, we used functional magnetic resonance imaging (fMRI) to investigate the neural underpinnings such reward-related performance-disrupting effects in a reward-modulated Stroop task humans. While associations task-relevant dimension (i.e., ink color) facilitated performance, behavioral detriments were found when task-irrelevant word meaning) implicitly...
Over the last two decades, congruency sequence effect (CSE) –the finding of a reduced following incongruent trials in conflict tasks– has played central role advancing research on cognitive control. According to influential conflict-monitoring account, CSE reflects adjustments selective attention that enhance task focus when needed, often termed adaptation. However, this dominant interpretation been called into question by several alternative accounts stress episodic memory processes:...
Decision-making involves weighing costs against benefits, for instance, in terms of the effort it takes to obtain a reward given magnitude. This evaluation process has been linked dorsal anterior cingulate cortex (dACC) and striatum, with activation these brain structures reflecting discounting effect on reward. Here, we investigate how cognitive influences neural choice processes absence an extrinsic Using functional magnetic resonance imaging humans, used effort-based decision-making task...
What is the neural locus of visual attention? Here we show that not fixed but instead changes rapidly to match spatial scale task-relevant information in current scene. To accomplish this, obtained electrical, magnetic, and hemodynamic measures attention from human subjects while they detected large-scale or small-scale targets within multiscale stimulus patterns. Subjects did know target before onset, yet attention-related activity between 250 300 ms varied according target. Specifically,...
Dopamine release in cortical and subcortical structures plays a central role reward-related neural processes. Within this context, dopaminergic inputs are commonly assumed to play an activating role, facilitating behavioral cognitive operations necessary obtain prospective reward. Here, we provide evidence from human fMRI that can also be mediated by task-demand-related processes thus extends beyond situations only entail extrinsic motivating factors. Using visual discrimination task which...
According to conflict-monitoring models, conflict serves as an internal signal for reinforcing top-down attention task-relevant information. While evidence based on measures of ongoing task performance supports this idea, implications long-term consequences, that is, memory, have not been tested yet. Here, we evaluated the prediction conflict-triggered attentional enhancement target-stimulus processing should be associated with superior subsequent memory those stimuli. By combining...
Associating stimuli with the prospect of reward typically facilitates responses to those due an enhancement attentional and cognitive-control processes. Such reward-induced facilitation might be especially helpful when mechanisms are challenged, as one must overcome interference from irrelevant inputs. Here, we investigated neural dynamics effects in a color-naming Stroop task by employing event-related potentials (ERPs). We found that behavioral potential-reward trials, compared no-reward...
Abstract Recent associative models of cognitive control hypothesize that can be learned (optimized) for task‐specific settings via associations between perceptual, motor, and representations, and, once learned, implemented rapidly. Midfrontal brain areas signal the need control, is subsequently by biasing sensory boosting or suppressing activity in processing task‐relevant task‐irrelevant information. To assess timescale this process, we employed EEG. In order to pinpoint implementation...
In the present study magnetoencephalographic recordings were performed to investigate neural mechanisms underlying stopping of manual responses. Subjects in a Stop-signal task which Go-stimuli (S1), requiring rapid motor response, sometimes rapidly followed by Stop-stimulus (S2) indicating withhold already initiated response S1. Success strongly depended on early perceptual processing S1 and S2 reflected magnetic N1 component. Enhanced facilitated execution movement, whereas enhanced favored...
We recently demonstrated with magnetoencephalographic recordings in human observers that the focus of attention visual search has a spatial profile consisting center enhancement surrounded by narrow zone sensory attenuation. Here, we report new data from 2 experiments providing insights into cortical processes cause surround show suppression appears tasks require scrutiny, is precise binding search-relevant features at target's location but not permit target discrimination without...