A5059707174- Spinal Fractures and Fixation Techniques
- Trauma and Emergency Care Studies
- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Spine and Intervertebral Disc Pathology
- Orthopaedic implants and arthroplasty
- Meningioma and schwannoma management
- Cystic Fibrosis Research Advances
- Animal Genetics and Reproduction
- Cancer Cells and Metastasis
- Clinical practice guidelines implementation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Pituitary Gland Disorders and Treatments
- Trauma Management and Diagnosis
- Diabetic Foot Ulcer Assessment and Management
- Orthopedic Infections and Treatments
- Cardiac Arrest and Resuscitation
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Cervical and Thoracic Myelopathy
- Total Knee Arthroplasty Outcomes
- Sexual Differentiation and Disorders
- Reconstructive Surgery and Microvascular Techniques
- Peripheral Artery Disease Management
- Intracranial Aneurysms: Treatment and Complications
Neurological Surgery
2018-2021
San Francisco General Hospital
2018-2021
University of California, San Francisco
2018-2021
University of California, Davis
2016
Elective fusions for degenerative spine disease have increased over the past two decades in USA, with variability complications and hospital costs. The additional service costs associated adverse perioperative events remain unknown. Our objective is to improve understanding of trends safety cost elective lumbar on a national scale.A weighted sample 1,526,386 adults undergoing fusion indications were identified National Inpatient Sample (NIS) years 2002-2014. Twelve categories major by...
Background Posterior fossa craniotomies can be complicated by cerebrospinal fluid (CSF) leaks, infection, meningitis, neurologic deficits, and intracranial hypotension caused defective closure of the dura. Secondary dural closures such as pericranial graft, muscle glue, sealants, or fat graft are used. However, there have been few studies examining use sealants with a polyethylene glycol polyethylenimine component. Objective We studied effect one sealant, Adherus® (HyperBranch Medical...
Purpose: Recent data suggest great variability in costs for surgical hospitalization spinal surgery. However, the magnitude of expenditures attributable to complications is unknown. The purpose this study describe cost care associated with and medical after cervical spine surgery.Materials Methods: A retrospective cohort utilizing National Inpatient Sample years 2002–2014 was conducted. weighted sample 901,508 adults undergoing elective fusion degenerative indications extracted using...
Abstract While cancer-associated fibroblasts (CAFs) and their pro-tumoral effects have been demonstrated in systemic cancers, CAFs had presumed absent glioblastoma given the lack of normal healthy brain. Here, we show that 5–26% (mean=12%) cells human glioblastomas express CAF markers α-SMA or PDGFR-β, morphologically resemble fibroblasts, transcriptomically by RNA-seq from other cancers. Glioblastoma were chemotactically attracted to glioblastoma-initiating stem (P=0.02). did not affect...
Instability is the most common indication for revision total hip arthroplasty in United States. Elevated-rim acetabular liners were introduced to minimize risk of posterior instability. We describe a patient with multiple dislocations secondary component subsidence leading As initially refused his femoral component, he was treated an elevated-rim liner. When this too dislocated, could not be reduced concentrically. During operative exposure stem revision, lipped aspect liner found have...
BACKGROUND: Spinal arteriovenous malformations (AVMs) are rare disease entities with significant morbidity if untreated. Risk factors of complications, hospitalization and costs-of-care remain in need characterization.METHODS: Using the National Inpatient Sample years 2002-2014, adult subjects spinal AVMs who underwent either laminectomy lesion excision or endovascular embolization were extracted using ICD-9-CM diagnostic code 747.82. Predictors inpatient hospital length stay (HLOS),...
Glioblastoma is an aggressive cancer with a dismal median survival of under two years. Recent studies have shifted the paradigm glioblastoma from homogenous mass tumor cells into complex organ containing interacting elements. We sought to determine whether cancer-associated fibroblasts (CAFs) are among these elements in glioblastoma. collected site-directed biopsies patients. Ex vivo analysis was performed using immunohistochemistry (IHC), quantitative reverse-transcription PCR (RT-qPCR),...
Category: Diabetes; Midfoot/Forefoot; Trauma; Other Introduction/Purpose: The level of amputation in patients with severe lower extremity pathology often presents a challenge. Surgeons are confronted deciding between transmetatarsal (TMA) or below-knee (BKA). Certainly, cases where candidates for TMA, the decision might seem rather straightforward. However, literature has demonstrated that minor foot amputations, like TMAs, have high rates revision and necessitate higher amputation. This...