Weibo You

ORCID: 0000-0002-9620-4045
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About
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Research Areas
  • Cancer-related gene regulation
  • TGF-β signaling in diseases
  • Antibiotic Resistance in Bacteria
  • Orthopedic Infections and Treatments
  • Amoebic Infections and Treatments
  • Infectious Diseases and Tuberculosis
  • Cancer Mechanisms and Therapy
  • Parasitic Infections and Diagnostics
  • Viral Infections and Vectors
  • Influenza Virus Research Studies
  • Hematological disorders and diagnostics

Lishui Central Hospital
2021

Wenzhou Medical University
2015-2016

Hypervirulent variants of Klebsiella pneumoniae (hvKp) that cause invasive community-acquired pyogenic liver abscess (PLA) have emerged globally. Little is known about the virulence determinants associated with hvKp, except for genes rmpA/A2 and siderophores (iroBCD/iucABCD) carried by pK2044-like large plasmid. Here, we collected most recent clinical isolates hvKp from PLA samples in China, performed clinical, molecular, genomic sequencing analyses. We found 90.9% (40/44) pathogens causing...

10.3389/fcimb.2016.00165 article EN cc-by Frontiers in Cellular and Infection Microbiology 2016-11-29

The occurrence of non-contiguous, multiple, and remote involvement tuberculous spondylitis is rare. clinical presentation in patients with multifocal musculoskeletal tuberculosis may closely mimic that multiple bone metastases, which makes the accurate diagnosis challenging. Herein, we report a case was misdiagnosed for 8 months as metastases. A 63-year-old male farmer Chinese Han ethnicity presented to us pain left side neck, right chest back 10 without typical symptoms. His past medical...

10.1186/s12879-016-1376-7 article EN cc-by BMC Infectious Diseases 2015-12-01

This study investigated the functional mechanism of transmembrane protein 100 (TMEM100) as a tumor inhibitor gene in CRC cells and offered reference for treatment CRC.The mRNA expression data were acquired from TCGA database to mine differentially expressed mRNAs. The role TMEM100 progression was evaluated by MTT, colony formation, scratch healing, Transwell assays. influence on TGF-β signaling pathway detected western blot.TMEM100 markedly lowly CRC. cell growth significantly suppressed...

10.1155/2021/5552324 article EN cc-by Gastroenterology Research and Practice 2021-08-11
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