A5046342727- Neurotransmitter Receptor Influence on Behavior
- Orthopaedic implants and arthroplasty
- Neuroscience and Neuropharmacology Research
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Receptor Mechanisms and Signaling
- Neurological disorders and treatments
- Parkinson's Disease Mechanisms and Treatments
- Psychology and Mental Health
- Nicotinic Acetylcholine Receptors Study
- Neural dynamics and brain function
- Mitochondrial Function and Pathology
- Hip and Femur Fractures
- Nietzsche, Schopenhauer, and Hegel
- Neuroscience and Neural Engineering
- Cholinesterase and Neurodegenerative Diseases
- Bacterial Infections and Vaccines
- Ion channel regulation and function
- Nitric Oxide and Endothelin Effects
- Memory and Neural Mechanisms
- Linguistics and Education Research
- Alzheimer's disease research and treatments
- Nerve injury and regeneration
- Neurological and metabolic disorders
- Hip disorders and treatments
IRCCS Humanitas Research Hospital
2023-2025
Humanitas University
2023-2025
Agostino Gemelli University Polyclinic
2020-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2006-2024
Università Cattolica del Sacro Cuore
2020-2024
University of Genoa
2023-2024
Campus Bio Medico University Hospital
2024
Università Campus Bio-Medico
2024
Universidade Católica de Pernambuco
2017
Mario Negri Sud Foundation
1998-2015
Electrophysiological and in vivo microdialysis were used to investigate compare the effect of tonic activation serotonin2C/2B (5-HT2C/2B) receptors on nigrostriatal mesolimbic dopaminergic (DA) function. Thus, extracellular single unit recordings neurochemically-identified DA neurons SNc VTA, as well simultaneous monitoring striatal accumbal release performed following administration unselective 5-HT2C/2B agonists, mCPP (m-chlorophenylpiperazine) MK 212...
Background: Periprosthetic joint infection (PJI) remains a significant and complex complication following total hip knee arthroplasty. This study aims to design, validate, assess machine learning (ML) model for predicting the likelihood of PJI in individuals undergoing revision arthroplasty procedures. Methods: A retrospective analysis was conducted on patients who underwent or between 1 January 2015 31 March 2021. Data were collected from preoperative clinical histories, laboratory results,...
Abstract The effects of acute and repeated nicotine administration on the extracellular levels dopamine (DA) in corpus striatum nucleus accumbens were studied conscious, freely moving rats by vivo microdialysis. Acute intraperitoneal (i.p.) injection (1 mg/kg) increased DA outflow both accumbens. Repeated daily mg/kg, i.p.) for 10 consecutive days caused a significant increase basal challenge with animals treated repeatedly this drug enhanced brain areas. However, effect was potentiated...
Abstract Primary cultures of cerebellar granule neurons (CGNs) were prepared from 8‐day‐old Wistar rats, and maintained in an appropriate medium containing a high (25 mM) concentration KCl. To induce apoptosis, culture was replaced with serum‐free (containing 5 mM KCl) 8 days after plating. Apoptosis measured by the terminal deoxynucleotidyl transferase‐mediated dUTP‐fluorescein nick end‐labeling (TUNEL) method, flow cytometry. Since there is evidence that increased formation reactive oxygen...
In vivo electrophysiological techniques were used to study the effect of nicotine on basal activity dopamine (DA)-containing neurons in substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) chloral hydrate-anesthetized rats. Acute i.v. injections (25-400 microg/kg) caused a dose-dependent increase firing rate bursting DA both SNc VTA. Repeated daily injection (1 mg/kg i.p.) for 10 consecutive days did not cause any significant change challenge with microg/kg i.v.) animals...