INTRODUCTION: Stereotactic radiosurgery (SRS) for metastatic spinal disease has high rates of local control. However, there is a paucity data evaluating how radiation to multiple levels or the pre-treatment volume metastases impact treatment effect and patient outcomes. METHODS: All patients with treated SRS at single-institution over seven-year interval were retrospectively reviewed. Baseline demographics, primary tumor histology, anatomic distribution metastases/epidural extension, dosing...

INTRODUCTION: Patient-reported outcome measures (PROMs) are pivotal in patient-centered care, offering insights into patients' perceptions of their health and quality life (QOL). Their application lumbar spinal stenosis (LSS) surgery outcomes reveals significant heterogeneity over time, underscoring the need for nuanced analytical methods that account time-dependent improvement QOL following surgery. METHODS: This single-institution retrospective cohort study investigated LSS patients...

<h3>ABSTRACT</h3> <h3>Background:</h3> Information regarding the treatment of high-grade spondylolisthesis (HGS) in adults has been previously described; however, previous descriptions evaluation and surgical management HGS do not represent more recent now established approaches. The purpose current review is to discuss concepts patients with HGS. <h3>Methods:</h3> Literature review. <h3>Results:</h3> diagnosed up 11.3% typically presents as nonspecific lower back pain. Regarding evaluation,...

Abstract Purpose Primary treatment of spinal ependymomas involves surgical resection, however recurrence ranges between 50 and 70%. While the association survival outcomes with lesion extent resection (EOR) has been studied, existing analyses are limited by small samples archaic data resulting in an inhomogeneous population. We investigated relationship EOR outcomes, chiefly overall (OS) progression-free (PFS), a large contemporary cohort ependymoma patients. Methods Adult patients diagnosed...

We present our experience in the management of symptomatic vertebral hemangiomas with epidural extension (SVHEE) using spine stereotactic radiosurgery (SSRS).

Study Design. Retrospective cohort study. Objective. The purpose of this study is to characterize the utilization and costs MNTs prior spinal fusion surgery in patients with symptomatic lumbar stenosis or spondylolisthesis. Summary Background Data. long-term maximal nonoperative therapy (MNT) can be substantial, current era bundled payments, duration conservative trials should reassessed. Methods. A large insurance database was queried for spondylolisthesis undergoing index decompression...

Study Design. Retrospective analysis. Objective. To investigate sex differences in opioid use after lumbar decompression and fusion surgery for patients with symptomatic stenosis or spondylolisthesis. Summary of Background Data. Recent studies have demonstrated higher prevalence chronic pain states greater sensitivity among women compared men. Furthermore, responsivity to pharmacological non-pharmacological treatments been observed. Whether perioperative exists undergoing spondylolisthesis...

Incidental durotomy is a common complication of posterior lumbar spine surgery, however effective and durable methods for primary repair remain elusive. Multiple existing techniques have previously been reported extensively described including sutured non-penetrating titanium clips. The use cranial aneurysm clips serves as safe alternative to obtain watertight closure dural tear. We performed retrospective review patients at single institution who underwent an incidental with clip during...

Retrospective cohort study.To compare the utilization of conservative treatments in patients with lumbar intervertebral disc herniations who were successfully managed nonoperatively versus failed therapies and elected to undergo surgery (microdiscectomy).Clinical records from adult an initial herniated between 2007 2017 selected a large insurance database. Patients divided into 2 cohorts: treated nonoperative that management opted for microdiscectomy surgery. Nonoperative utilized by groups...

Background: Subfascial drains are routinely used after multi-level anterior cervical discectomy and fusion (ACDF) procedures despite little evidence to support their use. Proponents of drain use argue that placement reduces the incidence post-operative hematomas surgical site infections (SSI). The aim this study is determine whether subfascial ACDFs associated with a decreased SSIs. Methods: This retrospective 321 consecutive adult patients (18 years older) degenerative stenosis undergoing...

Three generations of Co(iii)-salen complexes containing electron-deficient aromatic moieties (acceptors) have been synthesized. When electron-rich compounds (donors) were introduced, these designed to form catalyst assemblies through donor-acceptor interaction. For all three complexes, the addition a proper donor led higher catalytic efficiency in hydrolytic kinetic resolution (HKR) epichlorohydrin. The reaction rates are following order: Generation 3 > 2 1. interaction was verified by NMR...

Retrospective cohort study.The purpose of this study is to characterize the utilization and costs maximal nonoperative therapies (MNTs) within 2 years prior spinal fusion surgery in patients with symptomatic lumbar stenosis or spondylolisthesis.A large insurance database was queried for spondylolisthesis undergoing index 1-, 2-, 3-level decompression procedures between 2007 2016. This consists 20.9 million covered lives includes private/commercially insured Medicare Advantage beneficiaries....

Retrospective cohort study.To assess for racial differences in opioid utilization prior to and after lumbar fusion surgery patients with stenosis or spondylolisthesis.Clinical records from spondylolisthesis undergoing primary <3-level 2007 2016 were gathered a comprehensive insurance database. Records queried by International Classification of Diseases diagnosis/procedure codes insurance-specific generic drug codes. Opioid use 6 months prior, through 2 years was assessed. Multivariate...

In Brief Study Design. Retrospective cohort study. Objective. The purpose of this investigation was to evaluate the regional variations in use nonoperative therapies patients diagnosed with a lumbar intervertebral disc herniation 3 months prior undergoing microdiscectomy surgery. Summary Background Data. Regional management chronic pain conditions have been previously identified. Patients suffering from are typically treated brief course conservative attempting Whether differences exist...