A5003225691- Veterinary Oncology Research
- Mesoporous Materials and Catalysis
- Diet, Metabolism, and Disease
- Cervical Cancer and HPV Research
- Enzyme Catalysis and Immobilization
- Polymer Surface Interaction Studies
- Enzyme Structure and Function
- Amino Acid Enzymes and Metabolism
- Biosensors and Analytical Detection
- Diatoms and Algae Research
- Vector-Borne Animal Diseases
- Field-Flow Fractionation Techniques
- Freezing and Crystallization Processes
- Microbial infections and disease research
- Animal Disease Management and Epidemiology
- Cancer Diagnosis and Treatment
- Bacteriophages and microbial interactions
- Proteoglycans and glycosaminoglycans research
- Electrochemical sensors and biosensors
- Cancer, Hypoxia, and Metabolism
- Biological Research and Disease Studies
- Nail Diseases and Treatments
- Oral Health Pathology and Treatment
- Rheology and Fluid Dynamics Studies
- Poxvirus research and outbreaks
FHNW University of Applied Sciences and Arts
2016-2019
University of Veterinary Medicine Vienna
2010-2018
University of Vienna
2014
Graz University of Technology
2011-2013
The aetiology of genital squamous cell carcinoma (SCC) in horses remains unknown, but the similarity to disease man, for which papillomavirus infection has been shown be a causal factor, requires investigated horses.One or more novel papillomaviruses cause equine SCC and its associated premalignant lesions.DNA was extracted from samples performed rolling circle amplification, order identify closed circular DNA viral genomes within samples. amplified subcloned sequenced sequence compared that...
Abstract The fragile nature of most enzymes is a major hindrance to their use in industrial processes. Herein, we describe synthetic chemical strategy produce hybrid organic/inorganic nanobiocatalysts; it exploits the self‐assembly silane building blocks at surface grow an organosilica layer, controlled thickness, that fully shields enzyme. Remarkably, enzyme triggers rearrangement this layer into significantly soft structure. We demonstrate change stiffness correlates with biocatalytic...
Summary In January 2010, 18 months after excision of an ocular squamous cell carcinoma (SCC), a Connemara mare presented with anorexia and periorbital/parotideal lesions. Post mortem examination revealed these lesions as forming one entity, 2 additional growths in the retropharyngeal region left jugular groove, respectively. The were confirmed histopathologically SCCs. Using PCR, peripheral blood mononuclear cells (PBMCs) from 2008 tumour tissue, intact skin vulval mucosa screened for Equus...
Functional recognition imprints of virus-like particles, at the surface silica were generated following a strategy based on protein-templated polycondensation organosilanes.
Red complex bacteria, i.e. Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia, are involved in the onset progression of periodontal disease man, yet seldom inhabit oral cavity healthy individuals. Periodontal is also encountered horses, with equine odontoclastic tooth resorption hypercementosis (EOTRH) constituting a particular form disease. However, only little known about microbiome periodontitis-affected equids.We aimed to test hypothesis that red bacteria associated...
Equine hoof canker is a chronic pododermatitis of still unknown aetiology. Recent findings reported for 3 canker-bearing individuals are suggestive Treponema spp. having role in disease pathogenesis.Based on this hypothesised association, we assessed larger number DNA samples from hooves with and normal the presence treponemal DNA.Retrospective survey archived material.The study involved 71 archival, PCR-compatible extractions purified 59 obtained 26 equine cases 12 biopsies taken 9...
Abstract The fragile nature of most enzymes is a major hindrance to their use in industrial processes. Herein, we describe synthetic chemical strategy produce hybrid organic/inorganic nanobiocatalysts; it exploits the self‐assembly silane building blocks at surface grow an organosilica layer, controlled thickness, that fully shields enzyme. Remarkably, enzyme triggers rearrangement this layer into significantly soft structure. We demonstrate change stiffness correlates with biocatalytic...
There is a large body of evidence supporting bovine papillomavirus types 1 and 2 (BPV1; BPV2) as aetiological agents equine sarcoids. However, there conflicting data regarding BPV1/2 infection in sarcoid-free equids.Data obtained between 2007 2017 by screening sarcoids nonsarcoid tumours vs. samples from healthy equids are presented to help clarify this issue.Cross-sectional study.Tumour material horses, donkeys mules with confirmed (n = 130), suspected 120), or lesions 70), skin biopsies...
Abstract The design of nanomaterials that are capable specific and sensitive biomolecular recognition is an on‐going challenge in the chemical biochemical sciences. A number sophisticated artificial systems have been designed to specifically recognize a variety targets. However, methods based on natural detection using antibodies often superior. Besides greater affinity selectivity, can be easily coupled enzymatic act as signal amplifiers, thus permitting impressively low limits. possibility...
Enzyme shielding at the surface of silica nanoparticles was performed using different mixtures biomimetic building blocks. The performances nanobiocatalysts are strongly impacted by chemical composition layer.