Prostate biopsy guided by computer-assisted fusion of magnetic resonance imaging (MRI) and transrectal ultrasound (TRUS) images (MRI group) has not yet been compared with 12-core random (RB; control in a randomized controlled trial (RCT).To compare the rate detection clinically significant prostate cancer (csPCa) between two groups.This RCT included 175 biopsy-naïve patients suspicion for cancer, to an MRI group (n=86) (n=89) September 2011 June 2013.In group, two-core targeted (TB) MRI/TRUS...

<b>Objective: </b> To investigate three families and one sporadic case with a recessively inherited ataxic syndrome. <b>Methods: Clinical genetic studies were performed in six individuals. Southern blotting real time PCR used to detect deletions of mtDNA mutations the <i>POLG</i> gene identified using combination DHPLC direct DNA sequencing. <b>Results: The patients have distinctive, progressive disorder that starts episodic symptoms such as migraine-like headache or epilepsy. Ataxia, which...

Mutations in the catalytic subunit of mitochondrial DNA-polymerase gamma cause a wide spectrum clinical disease ranging from infantile hepato-encephalopathy to juvenile/adult-onset spinocerebellar ataxia and late onset progressive external ophthalmoplegia. Several these syndromes are associated with an encephalopathy that characteristically shows episodes rapid neurological deterioration development acute cerebral lesions. The purpose this study was investigate nature, distribution natural...

Clin. Otolaryngol. 2010, 35 , 97–103 Objectives: In this volumetric study of the vestibular schwannoma, we evaluated accuracy and reliability several approximation methods that are in use, determined minimum volume difference needs to be measured for it attributable an actual rather than a retest error. We also found empirical proportionality coefficients different methods. Design/setting participants: Methodological with investigation three VS measurement compared reference method was based...

To analyse and classify structural changes in the transverse ligament late stage of whiplash injury by use high-resolution MRI, to evaluate reliability our classification.Ninety-two whiplash-injured (2-9 years previously, mean 6 years) 30 non-injured individuals underwent proton-weighted MR imaging craniovertebral junction three orthogonal planes. Structural ligaments were graded twice (grades 1-3) based on increased signal, independently 3 radiologists with a 4-month interval. Inter-...

To analyse and classify structural changes in the transverse ligament late stage of whiplash injury by use high-resolution MRI, to evaluate reliability our classification.Ninety-two whiplash-injured (2-9 years previously, mean 6 years) 30 non-injured individuals underwent proton-weighted MR imaging craniovertebral junction three orthogonal planes. Structural ligaments were graded twice (grades 1-3) based on increased signal, independently 3 radiologists with a 4-month interval. Inter-...

Diving is associated with a risk of cerebral decompression illness, and the prevalence neurological symptoms higher in divers compared control groups. Microvascular dysfunction due to gas microembolism exposure hyperoxia are possible mechanisms, which may result diffusion perfusion deficits.To investigate if functional derangements microvasculature microstructure would be more prevalent among symptomatic divers.Magnetic resonance imaging (MRI) was performed 91 former 45 controls. Individual...

To propose an automatic method for estimating voxel-specific arterial input functions (AIFs) in dynamic contrast brain perfusion imaging.Voxel-specific AIFs were estimated blindly using the theory of homomorphic transformations and complex cepstrum analysis. Wiener filtering was used subsequent deconvolution. The verified simulated data evaluated 10 healthy adults.Computer simulations accurately differently shaped, normalized AIFs. Simple resulted underestimation flow values. Preliminary...

No large study has compared the yield of diffusion-weighted imaging (DWI) with clinical examination in order to differentiate lacunar stroke from other subtypes. This differentiation is important for guiding further investigations and treatment. Consecutive patients admitted cerebral infarction were classified according Oxfordshire Community Stroke Project scale. Based on DWI CT was as (LI) non-lacunar (NLI). Acute ischemic lesion <1.5 cm located subcortex or brainstem LI. All infarctions...

THREE CHILDREN WITH hydrocephalus and expanding cysts of the cavum septi pellucidi vergae are reported. In all patients, was present before persistent cava started to expand. The increased gradually, until they became cystic, but their growth did not affect size ventricles. Two patients were treated with internal cystoventricular shunts, causing a prompt collapse no change in concomitant hydrocephalus. third patient, expand only when previously implanted ventriculoperitoneal shunt failed...

A hypertensive response after ischemic stroke is frequent, yet its pathophysiology unknown. Mechanisms related to local damage, major vascular occlusion, and psychological stress due acute illness have been proposed. We assessed the natural course of blood pressure (BP) within first 24 h in groups patients with different characteristics. hypothesized that a consistent BP reduction, regardless location, time window from debut admission presence persistent would favor stress-related mechanism...

Transient ischemic attack has been redefined as a tissue-based diagnosis and MRI recommended the preferred imaging modality. We aimed to investigate whether an increased use of leads decrease in proportion TIA compared cerebral infarction. also sought see DWI-positive patients with transient symptoms <24 h differ from DWI-negative terms performed diagnostic investigations clinical characteristics.Patients admitted infarction or period 2006-2011 were prospectively registered. The annually...

OBJECTIVE Since the introduction of endovascular embolization, optimal treatment ruptured aneurysms has been debated. Much this debate based on results from large neurovascular centers and may not be applicable to small neurosurgical with low annual aneurysm loads. We think that centers, such as ours, also some interest. METHODS This study included 286 patients treated endovascularly or operated by senior investigator (KW) before November 2004. They all had an angiographically verified...

Mild cognitive impairment (MCI) is a subtle memory disorder not matching criteria for dementia. There evidence vascular comorbidity in several types of We hypothesized that neurovascular workup would detect high degree disease patients with MCI.In cooperation our clinic, amnestic MCI were referred to department investigation. The encompassed ultrasound examination carotid duplex including Intima-Media-Thickness (IMT) measurement, and transcranial Doppler (TCD) one-hour microemboli...

&lt;b&gt;&lt;i&gt;Background:&lt;/i&gt;&lt;/b&gt; MR diffusion-weighted imaging (DWI) has revolutionized neuroimaging and contributed to a tissue-based redefinition of transient ischemic attack (TIA). Stroke patients with DWI lesions may have neurological symptoms that resolve completely within 24 h, suggesting successful vessel recanalization. Prior studies stroke not found any predilection for in specific territory. Other have, however, reported an association between higher brain...

Study Design Retrospective study. Purpose The main purpose of this study was to investigate the union-rate spinous process after performing a osteotomy and whether union affects clinical results surgery. Overview Literature In present study, used facilitate access spinal canal when decompressive procedure for lumbar stenosis. aim evaluate rate its effect on procedure. Methods All patients were included in that underwent through be between January 1, 2007 December 31, 2007. Operation...