Hassan A. Alhazmi

ORCID: 0000-0002-9647-9006
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About
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Research Areas
  • Phytochemicals and Antioxidant Activities
  • Synthesis and biological activity
  • Computational Drug Discovery Methods
  • Analytical Methods in Pharmaceuticals
  • Phytochemistry and Biological Activities
  • Protein Interaction Studies and Fluorescence Analysis
  • Analytical Chemistry and Chromatography
  • Forensic Toxicology and Drug Analysis
  • Natural Antidiabetic Agents Studies
  • Protein purification and stability
  • Microfluidic and Capillary Electrophoresis Applications
  • Essential Oils and Antimicrobial Activity
  • Cholinesterase and Neurodegenerative Diseases
  • Natural product bioactivities and synthesis
  • Tryptophan and brain disorders
  • Electrochemical Analysis and Applications
  • Analytical chemistry methods development
  • Antibiotics Pharmacokinetics and Efficacy
  • Genomics, phytochemicals, and oxidative stress
  • SARS-CoV-2 and COVID-19 Research
  • Mass Spectrometry Techniques and Applications
  • Heavy Metal Exposure and Toxicity
  • Nanoparticle-Based Drug Delivery
  • Psychedelics and Drug Studies
  • Pharmaceutical Quality and Counterfeiting

Jazan University
2015-2025

Ministry of Health
2025

Pharmac
2024

Umm al-Qura University
2023

National Centre for Research
2023

Centre for Research and Information on Substance Abuse
2020-2022

University of Oradea
2022

American Association of Colleges of Pharmacy
2021

West Kordofan University
2020

Ministry of Education
2018

Proteins play crucial roles in the transportation and distribution of therapeutic substances, including metal ions living systems. Some can strongly associate, while others show low affinity towards proteins. Consequently, present work, binding behaviors Ca2+, Ba2+, Ag+, Ru3+, Cu2+ Co2+ with bovine serum albumin (BSA) were screened. BSA allowed to interact at physiological pH their interactions screened by using FT-IR spectroscopy. Spectra collected hydrated films over a range 4000–400 cm−1....

10.3390/scipharm87010005 article EN cc-by Scientia Pharmaceutica 2019-02-20

Photodegradation is an efficient strategy for the removal of organic pollutants from wastewater. Due to their distinct properties and extensive applications, semiconductor nanoparticles have emerged as promising photocatalysts. In this work, olive (Olea Europeae) fruit extract-based zinc oxide (ZnO@OFE NPs) were successfully biosynthesized using a one-pot sustainable method. The prepared ZnO NPs systematically characterized UV-Vis, FTIR, SEM, EDX XRD photocatalytic antioxidant activity was...

10.3390/antiox12061201 article EN cc-by Antioxidants 2023-06-01

Plasmonic nanoparticles such as Ag have gained great interest in the biomedical domain and chemical analysis due to their unique optical properties. Herein, we report a simple, cost-effective, highly selective colorimetric sensor of mercury(ii) based on

10.1039/d3ra05070j article EN cc-by-nc RSC Advances 2023-01-01

Ferroptosis is a newly discovered non-apoptotic and iron-dependent type of cell death. mainly takes place owing to the imbalance anti-oxidation oxidation in body. It regulated via number factors pathways both inside outside cell. closely linked with brain various neurological disorders (NDs). In human body, contains highest levels polyunsaturated fatty acids, which are known as lipid peroxide precursors. addition, there also connection glutathione depletion peroxidation NDs. There growing...

10.1016/j.heliyon.2024.e24786 article EN cc-by-nc-nd Heliyon 2024-01-19

The food chain, through vegetable consumption, is considered to be an important route of heavy metal exposure. Therefore, in this study, concentrations leafy vegetables grown the Jazan region Saudi Arabia were assessed using ICP-MS. Lettuce, radish, mint, parsley and jarjir (Arugula) selected for study subjected digestion HCl. results indicated that Fe level was highest all vegetables, while most contaminated vegetable. However, no tested exceeded maximum permissible limits set by FAO/WHO...

10.3390/ijerph20042984 article EN International Journal of Environmental Research and Public Health 2023-02-08

Abstract Transition metal dichalcogenides (TMDs) have been proven to possess many properties that are beneficial for the application of electrochemical detection. In this study, tungsten diselenide (WSe 2 ) was synthesized utilizing hydrothermal method and used modify platinum electrode. The behaviour WSe -modified electrode examined cyclic voltammetry (CV) impedance spectroscopy (EIS) methods. displays a wide linear range 5–100 μ M with correlation coefficient 0.986. detection limit found...

10.1088/1402-4896/acf07f article EN Physica Scripta 2023-08-15

Background: Alchornea laxiflora (Benth.) Pax & K. Hoffm. (A. laxiflora) has been indicated in traditional medicine to treat depression. However, scientific rationalization is still lacking. Hence, this study aimed investigate the antidepressant potential of A. using network pharmacology and molecular docking analysis. Materials methods: The active compounds targets depression-related were retrieved from public databases, such as PubMed, PubChem, DisGeNET, GeneCards, OMIM,...

10.3389/fphar.2024.1290398 article EN cc-by Frontiers in Pharmacology 2024-03-05

The regulation of gene expression is fundamental to health and life essentially carried out at the promoter region DNA each gene. Depending on molecular context, this may be accessible or non-accessible (possibility integration RNA polymerase not region). Among enzymes that control process, methyltransferase (DNMTs), are responsible for demethylation CpG islands, particularly regions, regulate transcription. aberrant activity these enzymes, i.e. their abnormal activity, can result in...

10.1016/j.cbi.2024.110907 article EN cc-by Chemico-Biological Interactions 2024-02-21

Salvadora persica L. (Salvadoraceae) is an evergreen shrub growing in the Middle East, Africa, and Southern Asia. It traditionally known as “miswak” used toothbrushes for treatment of toothache, gum diseases, boils, chest infection, gonorrhea, headache, spleen troubles, stomachache, ulcers. To best our knowledge, this first study aimed at conducting phytochemical, cytotoxic, antimicrobial investigations fruits (berries) S. collected from Jazan region Saudi Arabia. Analysis ethanol extract...

10.1155/2020/4521951 article EN cc-by Journal of Chemistry 2020-05-29
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