A5100692212- Ovarian cancer diagnosis and treatment
- Cancer-related molecular mechanisms research
- Gastric Cancer Management and Outcomes
- Bladder and Urothelial Cancer Treatments
- Luminescence and Fluorescent Materials
- RNA modifications and cancer
- Plant Disease Resistance and Genetics
- Cancer, Hypoxia, and Metabolism
- Gut microbiota and health
- Plant Molecular Biology Research
- Sulfur Compounds in Biology
- Gene Regulatory Network Analysis
- Dendrimers and Hyperbranched Polymers
- Immune Response and Inflammation
- Advanced Optical Sensing Technologies
- Virtual Reality Applications and Impacts
- Porphyrin and Phthalocyanine Chemistry
- Additive Manufacturing and 3D Printing Technologies
- Microbial Fuel Cells and Bioremediation
- Synthesis and Properties of Aromatic Compounds
- Cellular transport and secretion
- Polydiacetylene-based materials and applications
- Plant nutrient uptake and metabolism
- Wnt/β-catenin signaling in development and cancer
- Fullerene Chemistry and Applications
First Hospital of Lanzhou University
2025
Lanzhou University
2025
Fujian Agriculture and Forestry University
2024
University of Hong Kong - Shenzhen Hospital
2024
University of Hong Kong
2024
Zhongnan Hospital of Wuhan University
2019-2024
Wuhan University
2017-2024
China Jiliang University
2024
Zhejiang Lab
2023-2024
Hubei Cancer Hospital
2023
Cervical cancer is one of the most common female malignant tumors, with typical metabolism characteristics increased glycolysis flux and lactate accumulation. 2-Deoxy-D-glucose (2-DG) a inhibitor that acts on hexokinase, first rate-limiting enzyme in pathway. In this research, we demonstrated 2-DG effectively reduced impaired mitochondrial function cervical cell lines HeLa SiHa. Cell experiments revealed significantly inhibited growth, migration, invasion, induced G0/G1 phase arrest at...
Objective Asian females with ovarian cancer have different clinicopathological characteristics compared other races. However, an effective prognostic prediction tool is lacking. The goal of our study was to develop and evaluate nomograms for estimating overall survival cancer-specific in patients cancer. Methods We extracted data from 2010 2018 the Surveillance, Epidemiology, End Results database, focusing on Asian/Pacific Islander that had been diagnosed epithelial To find factors, least...
Abstract Eye‐tracking technology has been widely adopted in the extended reality (XR) industry, particularly applications such as foveated rendering, eye‐tracking interactions, and optical algorithm compensation, enhancing user immersion providing smooth virtual experiences. For near‐eye display systems integrated with capabilities, performance metrics contrast transfer function (CTF), distortion, chromaticity uniformity (CU), chromatic aberration (CA) vary shifts user's fixation point,...
Abstract Fokienia hodginsii ( F . ), belonging to the genus of Cupressaceae. has significant application value due its wood properties and great research in evolutionary studies as a gymnosperm. However, genome remains unknown large size gymnosperms genome. Pacific Bioscience sequencing, Hi‐C mapping, whole‐genome Bisulfite Sequencing (BS‐Seq), long‐read isoform sequencing (Iso‐Seq), direct RNA (DRS), quantitative proteomics, metabonomics analysis are employed facilitate assembly, gene...
Sortilin-related receptor 1 (SorL1) deficiency is a genetic predisposition to familial Alzheimer's disease (AD), but its pathology poorly understood. In SorL1-null rats, disorder of the global endosome-lysosome network (ELN) found in hippocampal neurons. Deletion amyloid precursor protein (APP) rats could not completely rescue neuronal abnormalities ELN hippocampus and impairment spatial memory young rats. These vivo observations indicated that APP one cargoes SorL1 regulation ELN, which...
Abstract The common pathogenesis of Alzheimer’s disease (AD) and Parkinson’s (PD) has been supported by biochemical, genetic molecular evidence. Mitochondrial dysfunction is considered to be the pathology in early AD PD. physiological regulation APP α-synuclein on mitochondria remains unclear, let alone whether they share regulatory mechanisms affecting development neurodegenerative diseases. By studying gene knockout rats, commonality maintaining mitochondrial function through calcium...
Abstract Objective We aimed to evaluate the ability of Adult Comorbidity Evaluation 27 (ACE-27) predict perioperative outcomes and survival in elderly women with advanced epithelial ovarian cancer (AEOC) undergoing cytoreductive surgery. Methods collected patients AEOC our hospital between January 1, 2012 2021. Patients younger than 65 years old or those non-epithelial were excluded. ACE-27 was applied retrospectively assess comorbidities selected patients, who then classified into two...
Abstract Synthesis of BODIPY oligomers has attracted increasing attention due to their intriguing properties and promising applications. Significant progress been made synthesize via post‐functionalization, either single‐bond linked or fully conjugated. This concept article highlights the recent developments oligomers, including synthetic routes, photophysical applications in areas NIR light absorbing dye, photodynamic therapy, bioimaging etc.
As a dynamic and reversible post-transcriptional marker, N
Abstract Indolo[3,2‐ b ]carbazole presents a π‐skeleton with remarkable electronic structure and interesting potential applications. It is, however, also associated ambiguity controversy. Herein, new derivatives of indolo[3,2‐ are reported they have enabled comprehensive study on the development n‐type organic semiconductor. Experimental computational studies show that has largely localized p ‐benzoquinonediimine moiety significant antiaromaticity. When substituted (4‐silylethynyl)phenyl...
A kind of polymer-based turn-on fluorescent probe for specific detection cysteine with high sensitivity has been developed.
At present, a majority of virtual reality (VR) technologies on the market employ static distortion correction by predistorting image. However, this compensation method is only effective when pupil remains in fixed position for display device. When moves within eye box VR device, image may deviate from target position, rendering ineffective. Due to optical asymmetry lens, different distortions can be perceived human as moves, which adversely affects user's visual experience. Therefore, it...
Abstract Objective : We aimed to evaluate the ability of Adult Comorbidity Evaluation 27 (ACE-27) predict perioperative outcomes and survival in elderly women with advanced epithelial ovarian cancer (AEOC) that underwent cytoreductive surgery. Methods collected patients AEOC our hospital between January 1, 2012 2021, excluding younger than 65 years or those non-epithelial cancer. ACE-27 was applied retrospectively comorbidities selected patients. The included were classified into two groups,...
Virtual reality (VR) displays have become increasingly popular in recent years, however, the nonidealities of these can hinder users from experiencing a truly immersive experience. In this paper, we review compensation process for micro‐organic light‐emitting diode (uOLED) and associated optical modules. We discuss full procedure panel method, as well distortion correction Additionally, provide remarks on mass‐production‐compatible metrology at end.
Background A comprehensive metabolism network of engineered E. coli is very important in systems biology and metabolomics studies. Many tools focus on two‐dimensional space to display pathways metabolic network. However, the usage three‐dimensional visualization may help understand better intricate topology regulatory networks. Methods We manually curated large amount experimental data (including pathways, reactions metabolites) from literature related with different types then utilized a...