Abstract Background The patterns of medication use among elderly inflammatory bowel disease patients vary due to several factors. This study aims present the outcomes immunomodulator therapy in both geriatric and non-geriatric patient groups, highlighting differences treatment effectiveness, reasons for discontinuation, incidence side effects between two groups. Methods A retrospective database was established by reviewing records aged 18 older who received at our clinic over a seven-year...

The effect of a gluten-free diet on the small intestinal mucosa in patients with celiac disease (CD) is unclear. occurrence mucosal healing and permanence villous atrophy under were investigated. symptoms, laboratory values, autoantibody levels, endoscopic biopsy samples 115 patients, 56 whom remission at different time periods since diagnosis, examined. Although 61.8% said they compliant diet, 48.7% remission. Sixty-seven percent (n = 77) CD reported least one symptom. Only weight loss was...

We aimed to evaluate the elevation of amylase and lipase enzymes in coronavirus disease 2019 (COVID-19) patients their relationship with severity COVID-19.In this study, 1378 COVID-19 infection were included. Relation elevated levels comorbidities was analysed. The effects haemodynamic parameters organ failure on pancreatic relations prognosis statistically analysed.The comprised 700 (51.8%) men 678 (%49.2) women. Of all patients, 687 (49.9%) had mild 691 (50.1%) severe infection. Amylase at...

Viral infections can cause acute pancreatitis. Idiopathic pancreatitis has an important proportion in the etiology of pancreatitis.To investigate rate development (AP) COVID-19 patients and to determine idiopathic this pancreatitis.A total 6.467 hospitalized with diagnosis were included study. Patients diagnosed AP based on Atlanta criteria identified. Etiological factors determined who developed compared etiological 315 non-COVID-19, before pandemic. was detected 0.1% COVID-19. While...

Primary tumor resection (PTR) in metastatic colorectal cancer (mCRC) has not been suggested by guidelines, since new systemic chemotherapy options have improved overall survival. However, the effect of PTR is still controversial mCRC. In this study, we aimed to evaluate on survival unresectable

Background: To investigage the thiol and disulphide levels in Helicobacter pylori -positive patients with non-ulcer dyspepsia investigate change these eradication therapy. Methods: This is a prospective observational study. A total of 320 diagnosed according to Rome IV criteria were included First, blood samples drawn from determine their serum levels. Endoscopic biopsy was performed on all specimens obtained examined pathologically. Patients positive for H. administered Blood second time,...

The initial treatment for fecal incontinence (FI) includes supportive and medical treatment. If the fails, biofeedback therapy (BFT) is recommended. However, there are limited conflicting results in literature supporting beneficial effect of BFT FI. aim study to analyze efficacy 126 patients who have FI due several causes.The data (88 females (69.8%) 38 males (30.2%)) were collected retrospectively. Colonoscopy, anorectal manometry (ARM), 3D-Endoanal ultrasonography (EAUS) performed all...

It is now known that with appropriate exercises, the functions of muscles in body ameliorate and increase strength. We applied pelvic floor muscle relaxation training exercises strengthen abdominal combination biofeedback therapy (BFT) to patients dyssynergic defecation (DD).Patients who met criteria for DD had no underlying organic cause were included this study. The electromyography (EMG) technique was used BFT therapy. Patients received at least six sessions BFT. considered successful...

The aim of this study was to present one-year real-life data our patients with CD who showed unresponsiveness and/or intolerance biological agents and then received ustekinumab treatment through an early access program.The retrospective reviewed the 52-week clinical 10 moderate or severe underwent therapy.The comprised 7 (70%) men 3 (30%) women a mean age 38 ± 11.3 years. Mean disease duration 13.5 8.5 pretreatment CDAI score 273.5 92 HBI 11.6 3.8. At end 8-week intravenous induction...

In chronic Hepatitis B virus (HBV) infection, certain individual and viral characteristics such as advanced age, presence of hepatic steatosis (HS), normal ALT levels, initially negative HBeAg HBV DNA, genotype the are associated with HBsAg seroclearance seroconversion. Herein, we report results our study evaluating association between hepatosteatosis HbsAg seroconversion.The clinical biochemical data patients CHB (HS) (HBsAg seroconversion, n:52, non-HbsAg n:352), rate development...

Vedolizumab, which is a monoclonal antibody that selectively binds to α4β7 integrin in the gastrointestinal system, may be an effective and safe treatment alternative those with anti-tumor necrosis factor-resistant inflammatory bowel disease.Patients administered vedolizumab due factor resistant or side effects between August 2017 November 2020 were included study. Crohn's patients evaluated using Harvey-Bradshaw index Simple Endoscopic Score for Disease, whereas ulcerative colitis Partial...

Amaç: Akut pankreatit (AP) tanısıyla hastaneye yatırılan hastalarda yatıştan itibaren hastalığın şiddetini belirlemek tedavinin planlaması için büyük önem arz etmektedir. RDW (Eritrosit Dağılım Hacmi) ve MPV’nin (Ortalama Trombosit pankreatitin öngörebilme özelliğinin olup olmadığını araştırmak amacıyla bu çalışmayı yaptık. Materyal metod: 2019-2022 yılları arasında AP nedeniyle 262 hastanın verileri retrospektif olarak incelendi. Hastalar Atlanta kriterleri referans alınarak şiddetine göre...

SUMMARY OBJECTIVE: We aimed to examine the effect of remission status on thiol–disulfide homeostasis in celiac patients and thus indirectly determine oxidative stress inflammation caused by non-compliance with diet. METHODS: Between February 2019 December 2021, 117 diagnosed disease were included this prospective randomized controlled study. In addition routine tests patients, thiol disulfide measurements made from blood both at beginning study end first year. RESULTS: While 52 (44.4%)...

Objective: To determine the histopathological findings in patients with HBeAg-positive chronic HBV infection (immunotolerant phase old terminology) and HBeAg-negative (inactive carrier terminology).

Background and Aims: Our understanding of the clinical outcomes double balloon enteroscopy in individuals with Peutz-Jeghers syndrome is limited. The purpose this study to assess enteroscopy’s effectiveness safety managing small intestinal polyps patients. Materials Methods: Data from 16 patients who underwent at our center between January 2007 March 2020 have been collected. included larger than 1 cm diameter. Results: Sixteen a total 79 procedures, 469 were found 76 oral/anal...

This article discusses Fasciola hepatica infection, a zoonotic parasite that lives in the liver bile ducts. A 31-year-old female patient was diagnosed with symptoms such as nausea, increased enzymes, and right upper quadrant pain for about year. The detected common duct by Endoscopic Ultrasound (EUS) removed Retrograde Cholangio Pancreatography (ERCP). Treatment performed 10 mg/kg triclabendazole. Eosinophilia, abdominal pain, dietary history are important clues diagnosis of infection....

AMA Ebik B, Ekin N, Bacaksiz F, et al. What is the incidence of celiac disease in patients with microscopic colitis? Why are these two diseases related?. Gastroenterology Review/Przegląd Gastroenterologiczny. 2023. doi:10.5114/pg.2023.126855. APA Ebik, B., Ekin, N., Bacaksiz, F., Uzel, A., Akkuzu, M. Z., & Ucmak, F. (2023). https://doi.org/10.5114/pg.2023.126855 Chicago Berat, Nazim Ferhat Ali Mustafa Z Feyzullah and Muhsin Kaya "What related?". Harvard M., Kaya, Goral, V. MLA Berat...

Pancreatic metastases account for 2% of pancreatic malignancies and are rare. Metastases to the pancreas originate from many organ systems in body but occur more frequently lung, breast, kidney, gastrointestinal tract. It may years after treatment primary tumor. Symptoms such as abdominal pain, weight loss, jaundice present at presentation, it can also be detected on radiologic imaging without any symptoms. In this article, we a case RCC metastasis 16 renal cell carcinoma (RCC) that was...

The treatment of solitary rectal ulcer (SRU) is challenging and controversial; generally, no response to conventional treatments can be obtained, particularly in patients with dyssynergic defecation (DD). We assessed the efficiency biofeedback therapy (BFT) who did not respond conservative had coexistence SRU DD.BFT responses, as well anorectal manometry rectoscopy results 20 DD, were assessed.Mean age was 32.5 years. Of patients, 12 female, 8 them male. An average sessions BFT performed on...

The aim of the study was to evaluate relationship among lower esophageal sphincter pressure (LESP), Helicobacter pylori (Hp), and gastroesophageal reflux (GER).The retrospective included patients with isolated hypertensive or hypotensive (LES) who underwent manometry in our gastroenterology motility laboratory had normal results. Demographic characteristics, complaints on admission, upper endoscopy findings, 24-h pH monitoring results, presence Hp gastric biopsy were evaluated.A total 1226...

Amaç: Bu çalışmadaki amacımız en sık kullanılan Helikobakter pylori (Hp) tedavi rejimlerinin HP eradikasyon başarı oranlarını saptamaktır.Materyal ve Metod: 2016 – 2020 yılları arasında üst gastrointestinal sistem endoskopisi sırasında pozitif saptanan tedavisi sonrası kontrol endoskopik biyopsi alınan hastalar geriye dönük olarak değerlendirildi. Hastalar rejimlerine göre 3 gruba ayrıldı; lansoprazol 30 mg 2x1, klaritromisin 500 amoksisilin 1000 2x1 14 gün alanlar (grup 1, n=20), bizmut...

Background: Colonic transit is delayed in two-thirds of patients with dyssynergic defecation. As a result, it's possible that defecation and slow constipation are linked. There scarcity research on the coexistence constipation, as well efficacy biofeedback therapy this group patients. 
 Methods: The results anorectal manometry MR defecography were used to make diagnosis colon time was measured help 24 specially marked markers. All given therapy. Results: average age 17 study 45.6 years....

Aim: Although nonspecific esophageal motility disorder(NEMD) is the most common diagnosis in manometry, unlike other primary disorders, it least known and studied disorder literature. Studies with a small number of patient groups have been reported The aim this study to share demographic clinical characteristics single center high-volume NEMD patients we followed up. 
 Material Method: was carried out retrospectively by examining records 391 diagnosed laboratory gastroenterology clinic...

Aim: This study aimed to investigate whether breastfeeding in early childhood affect the risk of devoloping inflammatory bowel disease (IBD).
 Materials and Methods: The data patients obtained from survey were compared their non-IBD siblings as a control group. relationship between demographic clinical chararecteristics IBD was also analyzed. 
 Results: 304 included study. 182 (59.9%) diagnosed with ulcerative colitis (UC), 122 (40.1%) Crohn’s (CD). CD group 332, UC 508. Compared...