A5009284137- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Cancer Mechanisms and Therapy
- Protein Tyrosine Phosphatases
- Organ Transplantation Techniques and Outcomes
- Lung Cancer Diagnosis and Treatment
- Heat shock proteins research
- S100 Proteins and Annexins
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer-related gene regulation
- Parasites and Host Interactions
- Lung Cancer Treatments and Mutations
- Renal cell carcinoma treatment
- Effects of Radiation Exposure
- Computational Drug Discovery Methods
- Blood Coagulation and Thrombosis Mechanisms
- Ubiquitin and proteasome pathways
- Nicotinic Acetylcholine Receptors Study
- Amoebic Infections and Treatments
- Neuroendocrine Tumor Research Advances
- Mitochondrial Function and Pathology
- Cancer Cells and Metastasis
- Monoclonal and Polyclonal Antibodies Research
- Diagnosis and treatment of tuberculosis
Taipei Medical University
2010-2022
Taipei Medical University-Shuang Ho Hospital
2013-2020
Christie's
2016
Taipei Medical University Hospital
2016
Cancer Genomics Centre
2016
Cancer Research Center
2016
National Taiwan Ocean University
2016
Eastern Cooperative Oncology Group
2016
Creative Commons
2016
Hepatocellular carcinoma (HCC) is a worldwide health problem. Currently, there no effective clinical therapeutic strategy for HCC. Smoking associated with several malignant diseases including cancers.However, the impact of smoking on HCC still unresolved. Retrospectively reviewed patients diagnosed between 1 January 2010 and 31 December 2015 at Taipei Medical University-Shuang Ho Hospital (Ministry Health Welfare). We found that was poor prognosis, especially recurrence patient survival...
Abstract Gemcitabine has been a commonly used therapeutic agent for treatment of pancreatic cancer. In the clinic, growing resistance to gemcitabine observed in patients with cancer, and investigation underlying mechanism is urgently required. The microRNA (miRNA)‐producing enzyme, Dicer, crucial maturation miRNAs, involved clinical aggressiveness, poor prognosis, survival outcomes various cancers, however, role Dicer acquired cancer still not clear. Here, we found that expression was...
The objective of this study is to evaluate the efficacy and safety profiles targeted medications, bevacizumab cetuximab, in combination with cytostatic drugs patients locally advanced or metastatic pancreatic cancer. In retrospective phase 2 study, a total 59 cancer were recruited received conventional (gemcitabine, cisplatin, fluorouracil) regimen (conventional plus cetuximab for first cycle) 2-week intervals four cycles. primary end-point was overall response rate. Secondary end-points...
Although the effectiveness of robotic hepatectomy (RH) has been evaluated in several studies, superiority RH over other approaches not definitely established. Therefore, present propensity score-matched cohort study, we compared and laparoscopic (LH) terms perioperative oncologic outcomes.This retrospective study included patients who underwent or LH for benign malignant liver lesions at a single center Taiwan any time between 2014 2020. Confounding factors, specifically age, sex, body mass...
Exposure to nicotine has been observed associated with tumor progression, metastasis, and therapy resistance of many cancers. Hepatocellular carcinoma (HCC) is one major cancer related the liver most difficult treat malignancies worldwide. The underlying mechanism in stimulation HCC tumorigenesis still not studied well.Classically, binds nicotinic acetylcholine receptors (nAChRs) induces downstream cancer-associated signaling pathways. Big data analysis used explore importance a7nAChR-Jak2...
Abstract Background Colorectal cancer (CRC) is the third most common in world. Genome‐wide association studies are a powerful method to analyze status of single‐nucleotide polymorphisms (SNPs) specific genes. Heat shock proteins (HSPs) were found be involved progression and chemoresistance. However, there still no further study about HSP beta‐1 (HSPB1 ) colorectal cancer. We proposed SNP HSPB1 may correlated with metastasis colon Methods recruited 379 patients categorized as four stages...
Survivin is an inhibitor of apoptosis protein and also plays a important role in the development several malignancies. To investigate association between survivin promoter –31 G/C (rs9904341) polymorphism bladder cancer (BC) risk. A total 200 pathologically confirmed BC cases unrelated cancer-free controls were recruited Chiayi Christian Hospital from August 2002 to May 2009. Polymerase chain reaction-restriction fragment length (PCR-RFLP) method was used determine at region. There...
We thank Dr. Daniel Seehofer and Robert Sucher for their valuable comments on our article suggestions further study designs (1). Our responses to the issues raised are outlined hereafter.