A5006441181- Research on Leishmaniasis Studies
- COVID-19 Clinical Research Studies
- Trypanosoma species research and implications
- Mosquito-borne diseases and control
- Infectious Diseases and Tuberculosis
- Gastrointestinal Tumor Research and Treatment
- Fecal contamination and water quality
- SARS-CoV-2 and COVID-19 Research
- Salmonella and Campylobacter epidemiology
- Viral Infections and Immunology Research
- Fungal Infections and Studies
- COVID-19 epidemiological studies
- Gastric Cancer Management and Outcomes
- Diagnosis and treatment of tuberculosis
- COVID-19 Impact on Reproduction
- COVID-19 Pandemic Impacts
- Helicobacter pylori-related gastroenterology studies
- Vector-borne infectious diseases
- Anesthesia and Pain Management
- Malaria Research and Control
- Antifungal resistance and susceptibility
- Viral Infections and Vectors
- COVID-19 and healthcare impacts
- Social Sciences and Policies
- Dermatological diseases and infestations
Centro Internacional de Entrenamiento e Investigaciones Medicas
2020-2025
Fundación Valle del Lili
2023-2025
Icesi University
2023-2025
Weatherford College
2024
University of Maryland, College Park
2024
Pedagogical and Technological University of Colombia
2014-2020
ObjectivesThe coronavirus disease 2019 (COVID-19) has become pandemic and turn in a challenge for Latin America. Understanding the dynamics of epidemic is essential decision making, to reduce health, economic, social impacts pandemic. The present study aimed estimate effective reproductive number (Rt) Severe Acute Respiratory Syndrome 2 (SARS-Cov2) infection during first 10 days outbreak seven American countries with highest incidence cases as March 23, 2020. Furthermore, we chose compare...
The quality and magnitude of the immune inflammatory responses determine clinical outcome Leishmania infection, contribute to efficacy antileishmanial treatments. However, precise mechanisms involved in healing or chronic immunopathology human cutaneous leishmaniasis (CL) are not well understood. Through sequential transcriptomic profiling blood monocytes, neutrophils, eosinophils over course systemic treatment with meglumine antimoniate, we revealed that a heightened sustained Type-I...
The high prevalence of patient absenteeism in medical appointments poses significant challenges for healthcare providers and patients, causing delays service delivery increasing operational inefficiencies. Addressing this issue is crucial the internal medicine department, a fundamental pillar comprehensive adult that manages various chronic complex conditions. To mitigate absenteeism, we present an innovative application machine learning models specifically designed to predict risk...
Salmonellosis is a major cause of morbidity and mortality one the most frequent etiologies diarrhea in world. Mortality due to Latin America still poorly understood, there lack studies that evaluate resistance clinical manifestations. The aims this study were characterize patients infected with Salmonella spp. seen university hospital Colombia between 2012 2021, trends antibiotic determine proportion overall related factors.Retrospective observational study. All microbiological diagnosis...
The multifactorial basis of therapeutic response can obscure the relation between antimicrobial drug susceptibility and clinical outcome. To discern relationship parasite to meglumine antimoniate (SbV) outcome cutaneous leishmaniasis, risk factors for treatment failure were considered in evaluating this ninety-one leishmaniasis patients corresponding strains Leishmania ( Viannia ) panamensis . Parasite 32 μg SbV/mL (plasma C max was evaluated primary human macrophages, PBMCs, U937...
There is limited evidence on the impact of erector spinae plane block (ESPB) as part multimodal analgesia in pediatric population undergoing cardiac surgery.A retrospective cohort study was conducted patients under 18 years age, who underwent surgery Risk Adjusted classification for Congenital Heart Surgery (RACHS-1) ≤3 by sternotomy. The aims to evaluate effect ESPB compared conventional (CA) relevant clinical outcomes: length hospital stay, ICU opioid consumption, time extubation,...
The co-occurrence of COVID-19 with endemic diseases is a public health concern that may affect patient prognosis and outcomes. objective this study was to describe the clinical characteristics patients dengue virus (DENV) SARS-CoV-2 co-infections compare their outcomes against those without dengue. A cross-sectional conducted in infection who attended single center Cali, Colombia, from March 2020 2021. All were tested by both real-time polymerase chain reaction for IgM/NS1 DENV included....
Sequential dengue virus (DENV) infections often generate neutralizing antibodies against all four DENV serotypes and sometimes, Zika virus. Characterizing cross-flavivirus broadly antibody (bnAb) responses can inform countermeasures that avoid enhancement of infection associated with non-neutralizing antibodies. Here, we used single cell transcriptomics to mine the bnAb repertoire following repeated infections. We identified several new bnAbs comparable or superior breadth potency known...
Abstract The immune response is central to the pathogenesis of cutaneous leishmaniasis (CL). However, most our current understanding in human CL derives from analysis systemic responses, which only partially reflect what occurs skin. In this study, we characterized transcriptional dynamics skin lesions during course treatment patients and identified gene signatures pathways associated with healing nonhealing responses. We performed a comparative transcriptome profiling serial lesion biopsies...
Understanding the intricate dynamics between different waves of COVID-19 pandemic and corresponding variations in clinical outcomes is essential for informed public health decision-making. Comprehensive insights into these fluctuations can guide resource allocation, healthcare policies, development effective interventions. This study aimed to compare characteristics at peak transmission points by including all patients attended during first four a referral center Colombia. In prospective...
<title>Abstract</title> The quality and magnitude of the immune inflammatory responses determine clinical outcome <italic>Leishmania</italic> infection, contribute to efficacy antileishmanial treatments. However, precise mechanisms involved in healing or chronic immunopathology human cutaneous leishmaniasis (CL) are not completely understood. Through sequential transcriptomic profiling blood monocytes (Mo), neutrophils (Nφ), eosinophils (Eφ) over course systemic treatment with meglumine...
Background: A high-throughput method using inductively coupled plasma mass spectrometry (ICP-MS) was developed and validated for the quantitative analysis of antimony in human peripheral blood mononuclear cells from patients with cutaneous leishmaniasis undergoing treatment meglumine antimoniate. Materials & methods: Antimony digested clinical samples 1% tetramethylammonium hydroxide/1% EDTA indium used as internal standard. Accuracy, precision stability were evaluated. Conclusion: Taking...
La histoplasmosis es una infección fúngica causada por Histoplasma ssp, que afecta principalmente el sistema respiratorio, mientras Staphylococcus aureus resistente a la meticilina (SARM) bacteria notoria ser los antibióticos y asociarse con infecciones graves. Presentamos un informe de caso mujer 33 años antecedente hidrocefalia se sometió colocación derivación ventriculoperitoneal (VP) posteriormente fue llevada al servicio urgencias debido debilidad muscular progresiva síntomas sugestivos...
Cutaneous leishmaniasis (CL) primarily affects people in remote settings with limited access to health services. mHealth tools offer an opportunity overcome knowledge gaps about clinical response treatment. We evaluated the validity of Guaral+ST mobile application for assessment therapeutic patients CL, through photographs lesions captured app by community volunteers. Patients confirmed CL were followed at weeks 13 and 26 after completion treatment assess two southwest Colombia. Direct...
Abstract Introduction Cardiovascular disease is the leading cause of morbidity and mortality worldwide. In Colombia, a Latin-American country, cardiovascular accounts for nearly 30% total deaths. The country has high heterogeneity in social conditions, health services ethnicity across regions. Health coverage by two main insurances as subsidized poor contributive formal workers. Purpose aim this study was to identify factors related with Methodology A cross-sectional using data from official...
—
—
Abstract Background The role of anti-N and anti-S antibody tests as a monitoring strategy for identifying patients at risk developing COVID-19 is not clearly elucidated. Our study explored in cohort hospital workers whether the positivity these antibodies linked to infection and/or vaccination was associated with decrease infections sought estimate predictive cut-off point development first 6 months measurement. Methods A prospective observational conducted among university Cali, Colombia....