А. В. Ковальчук

ORCID: 0000-0002-9681-9891
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About
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Research Areas
  • Viral Infections and Outbreaks Research
  • Viral Infections and Vectors
  • Bacillus and Francisella bacterial research
  • Poxvirus research and outbreaks
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • COVID-19 epidemiological studies
  • Gastrointestinal disorders and treatments
  • Pancreatitis Pathology and Treatment
  • Immune responses and vaccinations
  • Influenza Virus Research Studies
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Rabies epidemiology and control
  • Cancer Treatment and Pharmacology
  • Venous Thromboembolism Diagnosis and Management
  • Vector-Borne Animal Diseases
  • Transgenic Plants and Applications
  • Animal Disease Management and Epidemiology
  • Zoonotic diseases and public health

МИР 19 ® -первый в мире специфический противовирусный препарат для лечения COVID-19: разработка и доклинические исследования 1 Федеральное государственное бюджетное учреждение «Государственный научный центр «Институт иммунологии» Федерального медико-биологического агентства, 115522, г.Москва, Российская Федерация 2 автономное образовательное учр еждение высшего образования «Российский национальный исследовательский медицинский университет имени Н.И.Пирогова» Министерства здравоохранения...

10.33029/0206-4952-2023-44-3-270-290 article RU Immunologiya 2023-01-01

Objective of the investigation was to model adverse action vaccinia virus (VV), caused by oral immunization mice and evaluate efficacy its reduction, using therapeutic prophylactic drugs. Materials methods. Virological immunological research methods were used. Results conclusions. Reproduced pathological VV in orally infected mice. The ability reduce side effect protect from lethal infection demonstrated such preparations as Metisazon, Likopid, NIOCH-14 administered investigated schemes....

10.21055/0370-1069-2016-1-84-89 article EN cc-by Problems of Particularly Dangerous Infections 2016-03-01

Cellular immunity plays an important role in the pathogenesis and formation of protective immune defense against SARS‑CoV‑2 virus. The aim work was to study cellular rhesus monkeys applying flow cytometry after experimental infection with Materials methods . Male were intranasally inoculated virus, Isolate B strain hCoV-19/Russia/SP48-1226/2020 (abbreviated name U-2), at a dose 5.0 lg PFU. Using cytometry, levels 21 populations/subpopulations mononuclear cells peripheral blood animals...

10.21055/0370-1069-2022-3-53-60 article EN cc-by Problems of Particularly Dangerous Infections 2022-10-29

The outbreaks of the Zaire ebolavirus (ZE) disease (ZED) that have arisen in last decade determine need to study infection pathogenesis, formation specific immunity forming as well development effective preventive and therapeutic means. All stages fight against ZED spread require experimental sensitive laboratory animals, which are rhesus monkeys case this .The aim is evaluate monkey cellular following ZE by means flow cytometry (cytofluorimetry).Male were intramuscularly infected dose 15...

10.36233/0507-4088-64 article EN cc-by Problems of Virology 2021-09-18
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