A5100417145- Gallbladder and Bile Duct Disorders
- Monoclonal and Polyclonal Antibodies Research
- Viral Infectious Diseases and Gene Expression in Insects
- Bacteriophages and microbial interactions
- Protein purification and stability
- Pediatric Hepatobiliary Diseases and Treatments
- Corneal Surgery and Treatments
- Foreign Body Medical Cases
- Dysphagia Assessment and Management
- Functional Brain Connectivity Studies
- Esophageal and GI Pathology
- Metastasis and carcinoma case studies
- Advanced Neuroimaging Techniques and Applications
- Corneal surgery and disorders
- Gastrointestinal Tumor Research and Treatment
- Advanced MRI Techniques and Applications
- Inflammatory Bowel Disease
- vaccines and immunoinformatics approaches
- Antibiotic Resistance in Bacteria
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Immune Response and Inflammation
- Gastric Cancer Management and Outcomes
- Migraine and Headache Studies
- Intraocular Surgery and Lenses
- Ophthalmology and Visual Impairment Studies
Union Hospital
2024
Huazhong University of Science and Technology
2024
Second Affiliated Hospital of Harbin Medical University
2018-2022
Harbin Medical University
2018-2022
Shuguang Hospital
2022
Shanghai University of Traditional Chinese Medicine
2022
Zhujiang Hospital
2022
Southern Medical University
2022
WuXi AppTec (China)
2022
The Fourth People's Hospital
2018
Abstract Background Frameshift mutations in LRPAP1 are responsible for autosomal recessive high myopia human beings but its underlying mechanism remains elusive. This study aims to investigate the effect of defect on ocular refractive development and involved mechanism. Methods A lrpap1 mutant zebrafish line with homozygous frameshift mutation was generated by CRISPR/Cas9 technology confirmed Sanger sequencing. The phenotype analyzed calculating relative error (RRE) vivo photography...
This study aimed to provide profiles of microorganisms isolated from bile and antibiotic susceptibility patterns biliary tract infections (BTIs) in our center.A total 277 patients diagnosed with BTIs at the Second Affiliated Hospital Harbin Medical University 2011 2018 were included this study. records reviewed obtain clinical demographic data. Bile specimens prepared through endoscopic retrograde cholangiopancreatography (ERCP), percutaneous transhepatic cholangiodrainage (PTCD),...
Abstract Background Impaction of jujube pits in the upper gastrointestinal (GI) tract is a special clinical condition northern Chinese population. Endoscopic removal preferred therapy, but there no consensus on management strategies. We reported our individualized endoscopic strategies impacted GI tract. Methods In this retrospective study, we included 191 patients (male: 57; female: 134) who presented to hospital with ingestion between January 2015 and December 2017. Demographic...
ABSTRACT Background and Objectives There are two different endoscopic ultrasonographic manifestations of gastric signet ring cell carcinoma (GSRCC). No studies have been reported on the differences in clinical profiles patients based EUS examination. We aim to study variations clinicopathological characteristics between distinct GSRCC. Methods A total 302 with GSRCC confirmed by pathological examination who underwent were enrolled study. Based features, categorized into groups: type 1, where...
It is currently unclear whether endoscopic papillary balloon dilation (EPBD) associated with increased severe postendoscopic retrograde cholangiopancreatography pancreatitis (PEP)-related morbidity owing to conflicting reports. This study aimed investigate EPBD increases the risk of PEP and hyperamylasemia. Clinical data patients choledocholithiasis, treated at Second Affiliated Hospital Harbin Medical University from January 2015 December 2016 were analyzed. Patients divided into group...
To explore the changes and meaning of bilateral posterior cingulate cortex, hippocampus, precuneus, cerebellum lobe to all other parts whole brain for T2DM T2DR patients.The differences functional connectivity strengthen expressed were calculated analyzed between seed points after rs-fMRI scan by two sample t-test. Also The correlations with clinical parameters discussed.The had changed some regions comparing controls T2DM. also correlated parameters.The relevant emotion, memory, cognitive...
Objective To investigate the inhibitory effect of rapamycin, an mammalian target rapamycin (mTOR) pathway inhibitor, on proliferation, migration and fibrosis human pterygium fibroblasts (PFBs). Methods Pterygium tissues were collected from patients with primary who underwent surgical excision in Shenyang Fourth People's Hospital May to July 2015.The cultured vitro PFBs identified by anti-human vimentin immunofluorescence assay.The 3 5 generation cells used for experiments.The...
Abstract We explored the dynamic alterations of intrinsic brain activity and effective connectivity after acupuncture treatment to investigate underlying neurological mechanism in patients with migraine without aura (MwoA). The fMRI scans were separately obtained at baseline, first 12th sessions 40 MwoA. Compared HCs, MwoA showed mostly decreased amplitude low-frequency fluctuation (dALFF) variability regions differences. After treatment, dALFF rostral ventromedial medulla (RVM), superior...