A5047812239- Foot and Ankle Surgery
- Diabetic Foot Ulcer Assessment and Management
- Lower Extremity Biomechanics and Pathologies
- Nanoparticle-Based Drug Delivery
- Tendon Structure and Treatment
- Luminescence and Fluorescent Materials
- Nanoplatforms for cancer theranostics
- Orthopedic Surgery and Rehabilitation
- Molecular Sensors and Ion Detection
- Gastric Cancer Management and Outcomes
- Shoulder Injury and Treatment
- Cancer-related molecular mechanisms research
- RNA Interference and Gene Delivery
- Bioinformatics and Genomic Networks
- Supramolecular Self-Assembly in Materials
- Microfluidic and Bio-sensing Technologies
- Polydiacetylene-based materials and applications
- Graphene and Nanomaterials Applications
- Ferroptosis and cancer prognosis
- Bacterial Infections and Vaccines
- Breast Cancer Treatment Studies
- Neurogenesis and neuroplasticity mechanisms
- Thyroid Cancer Diagnosis and Treatment
- Cellular Mechanics and Interactions
- Monoclonal and Polyclonal Antibodies Research
Shanghai Jiao Tong University
2009-2025
Xinxiang Medical University
2025
Shanxi Medical University
2025
People's Hospital of Bishan District
2018-2024
Shandong University of Science and Technology
2024
University of Colorado Anschutz Medical Campus
2024
University of Colorado Denver
2022-2024
Renji Hospital
2012-2023
Wuxi Fourth People's Hospital
2019-2023
Jiangnan University
2019-2023
Streptococcus pneumoniae meningitis is a serious inflammatory disease of the central nervous system (CNS) and associated with high morbidity mortality rates. The processes initiated by recognition bacterial components contribute to apoptosis in hippocampal dentate gyrus. Brain-derived neurotrophic factor (BDNF) has long been recommended for treatment CNS diseases due its powerful neuro-survival properties, as well recently reported anti-inflammatory anti-apoptotic effects vitro vivo.In this...
Unique molecular self-assemblies were applied to the design of new materials that can achieve phosphorescence/fluorescence dual emission characteristics.
The exploration of emission pathways from high-excited states in organic luminogens has recently become prosperous owing to improved possibilities study so-called anti-Kasha's rule with the potential improving luminescent quantum efficiency. However, pathway switching among different rarely been addressed through external control. We here present a rational design and synthesis novel azulene-based emitter achieve responsive control its emissive switching. initially gives rise an S3-to-S0...
Abstract The fact that the lifetime of photoluminescence is often difficult to access because weakness emission signals, seriously limits possibility gain local bioimaging information in time‐resolved luminescence probing. We aim provide a solution this problem by creating general photophysical strategy based on use molecular probes designed for single‐luminophore dual thermally activated delayed fluorescence (TADF). structural and conformational design makes TADF strong both diluted an...
Intestinal fibrosis is one of the major serious complications Crohn's disease (CD). However, there are no effective antifibrotic drugs to treat intestinal in CD. Therefore, it important understand pathogenesis It has been reported that members miR-200 family essential regulation renal fibrogenesis. In this study, we analyzed function miR-200a and miR-200b fibrosis, which was induced by transforming growth factor β1 (TGF-β1) vitro. Furthermore, detected expression CD specimens, were divided...
Enantiodifferentiation is crucial in organic chemistry, pharmacochemistry, material and life science. However, it remains tremendously challenging to achieve a broad enantioselectivity different types of chiral substrates via single-material design. Here, we report coassembled organogel strategy with chirality transfer make an enantioselective generality possible. This coassembly contains two components: rigid molecular linker achiral block copolymer. Different from routine helically packed...
Degradation of mRNA by RNA interference is one the most powerful and specific mechanisms for gene silencing. However, insufficient cellular uptake poor stability have limited its usefulness. Here, we report efficient delivery siRNA via use biodegradable nanoparticles (NPs) made from monomethoxypoly(ethylene glycol)-poly(lactic-co-glycolic acid)-poly-l-lysine (mPEG-PLGA-PLL) triblock copolymers. Various physicochemical properties mPEG-PLGA-PLL NPs, including morphology, size, surface charge,...
In recent years, data has become one of the most important resources in digital economy. Unlike traditional resources, nature makes it difficult to value and contract. Therefore, establishing an efficient standard data-transaction market system would be beneficial for lowering cost improving productivity among parties this industry. Although numerous studies have been dedicated issue complying with regulations other issues such as privacy pricing, little work done provide a comprehensive...
We aimed to explore the clinical features and predictive factors for visual prognosis of neurosyphilis-associated optic atrophy (NSAOA). This retrospective observational study included 17 patients (33 eyes) with NSAOA who received standard anti-ocular syphilis treatment. LogMAR (logarithm minimum angle resolution) best-corrected acuity (BCVA), field, optical coherence tomography, were recorded at baseline, short-term (within one month after treatment), long-term (> 6 months) follow-up....
The corrosion inhibition by a triazole derivative (PAMT) on mild steel in phosphoric acid (H 3 PO 4 ) solution has been investigated weight loss and polarization methods. experimental results reveal that the compound significant inhibiting effect of H solution. It also shows good at higher concentration . Potentiodynamic studies have shown acts as mixed-type inhibitor retarding anodic cathodic reactions with predominant reaction. values efficiency obtained from measurements are agreement....
The morphology of foot joints is widely accepted as a significant factor in the development various disorders. Nevertheless, role first tarsometatarsal joint (TMT1) hallux valgus (HV) remains unclear, and its impact on TMT1 instability has not been fully explored. This study aimed to investigate potential correlation with HV instability.Weightbearing computed tomography (WBCT) scans 82 consecutive feet 79 controls were reviewed this case-control study. Three-dimensional (3D) models...
Biomaterial poly(lactic-co-glycolic acid) (PLGA), a FDA-approved material for clinical application, showed broad prospects in the past, but gradually can no longer meet present developments and requirements, which we synthesized monomethoxy(polyethylene glycol)-poly(d,l-lactic-co-glycolic acid)-poly(l-lysine) (mPEG-PLGA-PLL) (PEAL) have had some relevant reports. But studies on biocompatibility impacts of LA GA ratio (LA/GA = 60/40, 70/30, 80/20) main not yet been reported. Hemolysis...