- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Natural product bioactivities and synthesis
- Phytochemistry Medicinal Plant Applications
- Plant biochemistry and biosynthesis
- Probiotics and Fermented Foods
- Botanical Research and Applications
- Phytochemistry and Bioactivity Studies
- Protein Hydrolysis and Bioactive Peptides
- Bioactive Natural Diterpenoids Research
- Microbial Metabolites in Food Biotechnology
- African Botany and Ecology Studies
- Phytochemical compounds biological activities
- Food composition and properties
- Cassava research and cyanide
- Piperaceae Chemical and Biological Studies
- Chemical synthesis and alkaloids
- Agricultural and Food Sciences
- Antioxidant Activity and Oxidative Stress
- Sesquiterpenes and Asteraceae Studies
- Natural Antidiabetic Agents Studies
- Traditional and Medicinal Uses of Annonaceae
- Seaweed-derived Bioactive Compounds
- Seed and Plant Biochemistry
- Fungal Biology and Applications
Universidade Federal da Paraíba
2017-2025
Universidade Federal do Amapá
2023
Centro de Estudos em Psicologia da Saúde
2018
Apocynaceae is a botanical family distributed mainly in tropical and subtropical regions of the world. In Brazil, they comprise about 90 genera 850 species, inhabiting various types vegetation. Within this large family, genus Hancornia considered monotypic, with its only species speciosa Gomes. Antihypertensive, antidiabetic, antiviral activities are described for species. Despite having been target some studies, knowledge chemical composition still limited. study, phenolics H. leaves were...
This study evaluated the physicochemical properties, antioxidant capacity, and potential prebiotic effects on human intestinal microbiota of freeze-dried Opuntia dillenii (Ker Gawl). Haw] (Cactaceae) cladodes (FDOd). FDOd had high levels total fiber (52.36 g/100 g), especially soluble (33.36 as well minerals, such potassium (4415.49 mg/100 calcium (1593.25 magnesium (853.55 phosphorus (209.04 chlorophyll content (912.00 presence various phenolic compounds, catechin (41.00 myricetin (785.00...
A laparoscopia tem se consolidado como uma abordagem promissora no manejo de traumas torácicos fechados, possibilitando diagnósticos mais precisos e intervenções menos invasivas. Este estudo realizou revisão narrativa com o objetivo avaliar a eficácia segurança da diagnóstico tratamento desses traumas. metodologia incluiu seleção artigos publicados entre 2010 presente momento, utilizando bases dados indexadas aplicando critérios rigorosos inclusão exclusão. Os resultados indicam que...
The essential oil from leaves of Croton grewioides Baill was obtained by hydrodistillation using Clevenger apparatus, and its chemical composition analyzed GC-MS, where 18 compounds were identified, mostly as monoterpenes (55.56%) sesquiterpenes (44.44%), in which the major constituent α-pinene (47.43%). (EOCg) compound (α-pinene) evaluated modulators antibiotic resistance strain SA-1199B IS-58 Staphylococcus aureus that overexpresses efflux protein. minimum inhibitory concentrations (MICs)...
Miconia albicans (Sw) Triana (Melastomataceae), a medicinal plant widely used by practitioners of folk medicine in the northeast Brazil, has been to treat chronic inflammatory disorders, such as rheumatoid arthritis (RA) and other joint conditions. Oddly, there is little research on species. We aimed evaluate anti-arthritic anti-inflammatory profile ethanolic leaf extract M. (EEMA), well perform dereplication quantification HPLC-DAD-ESI-/MS/MS. The compounds present extracts were identified...
Fungal infection is a public health problem. Antifungal agents resistance often seen in common Candida albicans the hospital environment. Nanoparticles have been reported literature as promising development of products. The toxicity, antioxidant and antifungal activity cerium oxide nanoparticles (CeNP) were evaluated. After synthesis characterization physicochemical properties, new CeNP was evaluated by biological tests activity. scavenging free radicals 1,1-diphenyl-2-picrylhydrazyl hydrate...
This study evaluated the efficacy of potentially probiotic fruit-derived Lactobacillus isolates, namely, L. paracasei 108, plantarum 49, and fermentum 111, to remove aflatoxin M1 (AFM1) from a phosphate buffer solution (PBS; spiked with 0.15 µg/mL AFM1). The examined isolates (approximately 109 cfu/mL) as viable non-viable cells (heat-killed; 100 °C, 1 h) AFM1 was measured after 24 h at 37 °C. recovery bound bacterial washing PBS also evaluated. Levels in were high-performance liquid...
This study evaluated the effect of Mucuna pruriens (MP) administration on neuroinflammation and behavioral murinometric parameters in obese rats. Proximate composition, oligosaccharide phenolic compound profile MP were determined. Wistar adult male rats randomized into healthy (HG) group (OG). The HG consumed a control chow diet while OG cafeteria for eight weeks. Then, they subdivided into: Healthy (HG); with (HGMP); Obese (OG); (OGMP), consumption respective diets remaining another weeks,...
Eriodictyon californicum is a species belonging to Boraginaceae family, popularly known as “yerba santa” and used in folk medicine treat rheumatism, headaches, inflammation, respiratory complications. In the present work, we performed phytochemical analyses of extracts from leaves E. order isolate its chemical constituents. According thin-layer chromatography (TLC) analyses, preliminary screening indicated presence anthocyanins derivatives, flavonoids, condensed hydrolysable tannins....
Zornia brasiliensis Vogel (Leguminosae) is a species popularly known in Brazil as "urinária", "urinana", and "carrapicho", it used diuretic the treatment of venereal diseases. A specific methodology to obtain saponin-enriched fraction high-performance liquid chromatography coupled with diode array detection, ion trap mass spectrometry, TOF-MS (HPLC-DAD-ESI-MS/MS) was applied for analysis triterpene saponins. The MS MS/MS experiments were carried out by ionization negative mode. Molecular...
This current study presents the phytochemical analysis of Croton velutinus, describing phenylpropanoids obtained from this species. The fractionation roots hexane extract led to isolation four new derivatives, velutines A–D (1–4) and three known (5–7). Their structures were established based on spectroscopic (1D-2D NMR; HRMS IR) analysis. Cytotoxic, trypanocidal anti-inflammatory activities compounds 1–7 evaluated. Only 2 5 showed cytotoxic activity against cancer cell lines (B16F10, HL-60,...
The essential oil from Conyza bonariensis (Asteraceae) aerial parts (CBEO) was extracted by hydrodistillation in a Clevenger-type apparatus and characterized gas chromatography–mass spectrometry. antitumor potential evaluated against human tumor cell lines (melanoma, cervical, colorectal, leukemias), as well non-tumor keratinocyte using the MTT assay. effect of CBEO on production Reactive Oxygen Species (ROS) DCFH-DA assay, protection assay antioxidant N-acetyl-L-cysteine (NAC) also...
This study represents the first phytochemical analysis of Stillingia loranthacea (S. loranthacea) and describes new terpenoids obtained from root bark this species. The fractionation hexane extract led to isolation two 28-nor-taraxarenes derivatives, loranthones A B (1 2), four tigliane diterpenes (5–8), three known (9–11), flexibilene diterpenes, tonantzitlolones A–C (12–14). investigation these compounds use a molecular networking-based prioritization approach afforded other...