- Antimicrobial Peptides and Activities
- Bacterial biofilms and quorum sensing
- Bacteriophages and microbial interactions
- Bacterial Infections and Vaccines
University of Nottingham
2021
Abstract Bacterial biofilms represent a challenge to the healthcare system because of their resilience against antimicrobials and immune attack. Biofilms consist bacterial aggregates embedded in an extracellular polymeric substance (EPS) composed polysaccharides, nucleic acids proteins. We hypothesised that carbohydrates could contribute recognition Pseudomonas aeruginosa by engaging C-type lectins. Here we show binding Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing...
Abstract Bacterial biofilms represent a challenge to the healthcare system because of their resilience against antimicrobials and immune attack. Biofilms consist bacterial aggregates embedded in an extracellular polymeric substance (EPS) composed carbohydrate polymers, nucleic acids proteins. Carbohydrates within P. aeruginosa include neutral mannose-rich Psl, cationic Pel N -acetyl-galactosamine -acetyl-glucosamine. Here we show that display ligands for C-type lectin receptors mannose...