A5000069173- Antimicrobial Peptides and Activities
- Bacterial biofilms and quorum sensing
- Immune Response and Inflammation
- Inhalation and Respiratory Drug Delivery
- Viral Infections and Vectors
- Hemoglobinopathies and Related Disorders
- Bacterial Infections and Vaccines
- Immunodeficiency and Autoimmune Disorders
- Immune responses and vaccinations
- Family Dynamics and Relationships
- Cystic Fibrosis Research Advances
- Assisted Reproductive Technology and Twin Pregnancy
- Immune cells in cancer
- Inflammasome and immune disorders
- Blood groups and transfusion
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Reproductive Health and Technologies
University of Nottingham
2014-2021
Kwame Nkrumah University of Science and Technology
2013
The desire of many young women to become parents may be influenced by the premium placed on children society. In Africa, are highly valued for social, cultural and economic reasons. Infertile childless in Africa therefore confronted with a series societal discrimination stigmatization which lead psychological disorders such as anxiety depression. Even though some research has been done prevalence infertility Ghana, very little is known about impact childlessness among infertile women....
Abstract Bacterial biofilms represent a challenge to the healthcare system because of their resilience against antimicrobials and immune attack. Biofilms consist bacterial aggregates embedded in an extracellular polymeric substance (EPS) composed polysaccharides, nucleic acids proteins. We hypothesised that carbohydrates could contribute recognition Pseudomonas aeruginosa by engaging C-type lectins. Here we show binding Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing...
Pseudomonas aeruginosa causes infections in patients with compromised epithelial barrier function. Multiple virulence factors produced by P. are controlled quorum sensing (QS) via 2-alkyl-4(1H)-quinolone (AQ) signal molecules. Here, we investigated the impact of AQs on PAO1 infection differentiated human bronchial cells (HBECs). The pqsA-E operon is responsible for biosynthesis including 2-alkyl-3-hydroxy-4-quinolones, 4-hydroxy-2-alkylquinolines, and 4-hydroxy-2-alkylquinoline N-oxides as...
Macrophages are important orchestrators of inflammation during bacterial infection, acting as both effector cells and regulators neutrophil recruitment life span. Differently activated macrophage populations with distinct inflammatory microbicidal potentials have been described. Our previous work unveiled a positive negative correlation between levels gamma interferon (IFN-γ) interleukin-17A (IL-17A), respectively, lung function in cystic fibrosis, particularly patients chronically infected...