Puspita Eka Wuyung

ORCID: 0000-0002-9737-4409
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About
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Research Areas
  • Reconstructive Surgery and Microvascular Techniques
  • Reproductive tract infections research
  • Tendon Structure and Treatment
  • Medicinal Plant Research
  • Pain Mechanisms and Treatments
  • Myofascial pain diagnosis and treatment
  • Reproductive System and Pregnancy
  • Tissue Engineering and Regenerative Medicine
  • Andrographolide Research and Applications
  • Advanced biosensing and bioanalysis techniques
  • Pelvic floor disorders treatments
  • Skin Protection and Aging
  • Urological Disorders and Treatments
  • Sperm and Testicular Function
  • Toxin Mechanisms and Immunotoxins
  • Breast Implant and Reconstruction
  • CRISPR and Genetic Engineering
  • RNA Interference and Gene Delivery

University of Indonesia
2022-2025

Techno India Group (India)
2025

Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2022-2025

Objective: This study aims to investigate the possibility of additive cytotoxic effects cisplatin and Andrographis paniculate (Burm. f.) Nees(AP) via apoptotic, cell cycle angiogenesis pathways. Methods: CC50 cisplatin, AP Andrographolide (AG) were determined by viability SKOV3 after its exposure these substances. cells then divided into 6 experimental groups: one negativecontrol group, with alone, three where was combined AP, ½CC50 1.5CC50 respectively. The effect or AG evaluated through...

10.22159/ijap.2025v17i1.52654 article EN International Journal of Applied Pharmaceutics 2025-01-07

Objective: The aim of this study is to determine narrowband UVB (NB-UVB) irradiation’s effect on the promotion skin cancer, particularly its DNA damage, oxidative stress, inflammation, and histological changes in Wistar rat skin. Materials Methods: rats were selected for randomly divided into control, dimethylbenzanthracene (DMBA), DMBA+NB-UVB groups. given a single dose DMBA exposed NB-UVB 3 times week 10 weeks. radiation started with 1 minimal erythema dose, which equivalent 3.192 J/cm²....

10.5455/javar.2024.k861 article EN cc-by Journal of Advanced Veterinary and Animal Research 2025-01-01

Sexual violence, including sexual intercourse, can occur in women experiencing vaginal discharge, particularly cases of candidiasis. In candidiasis, the microbiome undergoes changes that could serve as a diagnostic indicator or evidence activity. The aim this study was to assess effects semen insemination on profile candidiasis rats and determine its forensic investigations violence. An experimental carried out using Wistar strain (Rattus norvegicus), consisting four male (for spermatozoa...

10.52225/narra.v5i1.1256 article EN Narra J 2025-02-05

Introduction: Streptozotocin (STZ), a widely used diabetogenic agent, induces diabetes in animal models, yet crucial details like its preparation and dosage are often overlooked. We induced diabetic Achilles tendinopathy rats using streptozotocin excess body fat, assessing Transforming Growth Factor-beta (TGF-β) interleukin-6 (IL-6) blood levels. This study aimed to create model Sprague-Dawley combination of high-fat diet (HFD) streptozotocin. Methods: In this study, 8 male were divided into...

10.15562/bmj.v13i3.4971 article EN Bali Medical Journal 2024-07-03

Sexual violence is a global issue affecting individuals regardless of their relationship to the perpetrator or setting. Microscopic examination spermatozoa from vaginal swabs crucial in investigating cases sexual intercourse determine time crime. Factors such as pH and neutrophil count influence motility persistence vagina, particularly conditions like candidiasis, highlighting need for further research this area. This study aimed effect on vagina with candidiasis. An experimental was...

10.52225/narra.v4i2.823 article EN cc-by-nc Narra J 2024-06-21

Clustered regularly interspaced short palindromic repeats (CRISPR)-associated nuclease 9 (CRISPR/Cas9) offers a robust approach for genome manipulation, particularly in cancer therapy. Given its high expression triple-negative breast (TNBC), targeting survivin with CRISPR/Cas9 holds promise as therapeutic strategy. The aim of this study was to design specific single guide ribonucleic acid (sgRNA) permanently knock out the gene, exploring potential while addressing off-target effects....

10.52225/narra.v4i3.1177 article EN cc-by-nc Narra J 2024-11-16

Mesh-augmented surgery with polypropylene meshes (PPMs) is often used in urogynecology and pelvic reconstructive surgery. However, the various complications that arise from its integration process have resulted a decrease number of mesh-augmented surgeries performed worldwide. An approach to improving mesh-tissue coating PPMs anti-inflammatory wound-healing molecules, such as platelet-rich plasma (PRP), which component biotechnologies are capable accelerating wound healing. Estrogen also...

10.2196/37942 article EN cc-by JMIR Research Protocols 2022-05-01
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