A5103094616- Skin Protection and Aging
- Acne and Rosacea Treatments and Effects
- melanin and skin pigmentation
- Phytochemicals and Antioxidant Activities
- Photodynamic Therapy Research Studies
- Dermatologic Treatments and Research
- Advancements in Transdermal Drug Delivery
- Free Radicals and Antioxidants
- Pharmacological Effects of Natural Compounds
- Retinal Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Inflammatory mediators and NSAID effects
- Atherosclerosis and Cardiovascular Diseases
- Optical Imaging and Spectroscopy Techniques
Henry Ford Health System
2020-2022
Michigan United
2019-2022
Beaumont Hospital, Royal Oak
2020-2021
Beaumont Health
2020
Botsford Hospital
2018-2019
Henry Ford Hospital
2018
The role of topical antioxidants (AOs) on visible light plus ultraviolet A1 (VL+UVA1)-induced skin changes were evaluated. Twenty subjects with phototypes (SPTs) I-VI had placebo and concentrations an AO blend applied to their back (AO 0.5%, 1.0% 2.0%). Treated control sites irradiated VL+UVA1. Colorimetric diffuse reflectance spectroscopy (DRS) assessments performed immediately, 24 h 7 days after irradiation. Subjects SPT I-III erythema that faded within h, while IV-VI persistent...
Solar radiation is a major contributor to the development of skin cancer. Recent studies have shown that visible light (VL), portion solar spectrum, induces biologic effects on skin. Ultraviolet filters in currently available broad-spectrum sunscreens do not offer protection against VL. This study was designed identify spectral characteristics responses induced by VL, which can be utilized for time efficient vivo VL testing. Thirty-one subjects were irradiated with source emitting less than...
Summary Background/Purpose Screening antinuclear antibody (ANA) is not recommended prior to initiating narrowband ultraviolet B (NBUVB) phototherapy in vitiligo patients, unless concern for photosensitivity exists. Guidelines on prescribing NBUVB patients with positive ANA are unavailable, prompting this study uncover trends. Methods This retrospective chart review investigated 12 years of age or older a diagnosis between January 2015 and September 2017, serum ANA, phototherapy. Demographic...
Background Postinflammatory hyperpigmentation (PIH) is a common, acquired pigmentary disorder of the skin associated with significant quality-of-life impairment, especially in individuals colour. Current treatment for PIH limited, largely due to poor understanding disease pathogenesis and lack representative model. Objectives This study intended further develop, update validate our previously designed vivo model acne-induced PIH/postinflammatory erythema (PIE) using different concentrations...
Vitiligo is an autoimmune depigmentation disorder. Narrowband ultraviolet B (NB-UVB) phototherapy currently the standard of care for generalized vitiligo. The combination visible light (VL) with UVA1 (VL+UVA1) has recently been shown to induce skin pigmentation. This pilot study aims compare efficacy VL+UVA1 versus NB-UVB in subjects Preliminary findings suggest a more robust erythematous response post-irradiation at site when compared sites. Study results will provide information regarding...